Spectrum of Interface dermatitis : An Observational study'
Keywords:
Interface, Dermatitis, Lichen
Abstract
Inroduction: Major role of a dermatopathologists is to try to make specific diagnosis of inflammatory skin diseases. IFD means inflammatory infiltrate that abuts or obscures the dermo-epidermal junction in askin biopsy.This type of reaction is also seen in skin disorders associated with systemic illness like LE and skin changes of potentially fatal disorders such as Graft versus host disease, S-J syndrome and toxic epidermal necrolysis. Aims & Objectives- 1)To study the histopathology of interface dermatitis.(2)To study the common types of skin manifestations in interface dermatitis.(3)To determine other histological features associated with interface dermatitis.4)To identify the clinical concordance of various types of interface dermatitis.Methods : Present study is a retrospective , Hospital based study. Ethical consideration was taken. Study duration was Jan 2012 to Dec 2015.Results: In the present study, a total of 121 cases of IFD were studied, the majority of which [65] presented as papulo- squamous [ papules and plaques ] lesions. Of theses 121 cases, the most common type of IFD was LP and its variants (53.71 %).The next common was LDE (8.26 %) followed by PL(7.4% ). The least common was LN (0.8 % ) and dermatomyositis (1.6 %). Female preponderance was noted in case of IFD [ 59.9 % ]. The percentage of clinical concordance was good in cases of LP & its variants (90.77 %), DLE ( 83.33%) and in Dermatomyositis. Conclusion- A good clinicopathologic correlation is absolutely essential for the final diagnosis of IFD. DOI: 10.21276/AABS.1460References
1. Crowson AN, Magro CM, Mihm MC Jr. Interface Dermatitis. Arch Pathol Lab Med 2008 Apr; 132 (4) : 652-66.
2. Le Boit PE. Interface Dermatitis. How specific are its histopathologic features? Arch Dermatol 1993; 129:1324-28
3. Virendra Sehgal, G Srivastava et al. Lichenoid tissue reaction/Interface dermatitis: Recognition, classification, etiology & clinicopathological overtones. Indian Journal of Dermatology ,venerology and Leprology 2011; Vol 77: Issue 4:418-430.
4. Tilly JJ, Drolat BA, Esterley NB et al. Lichenoid eruptions in Children. J Am Acad Dermato;2004;51:606-24.
5. Rajiv Joshi. SYMPOSIUM DERMATOPATHOLOGY. Indian Journal of Dermatology, Venereology & Leprology 2013;79:3: 349-59.
6. Philip Le boit. Dermatitis involving dermo-epidermal junction. In:Maize JC. Burgdorf WH, Hurt MA, Le Boit PE, Metcalf JS, Smith T et al, editors. Cutaneous Pathology. Philadelphia: Churchill Livingstone:1998.pg 87-145.
7. Weedon D. The Lichenoid Reaction Pattern. In: Weedon D, editor. Skin Pathology. 2 nd ed. New York: Churchill Livingstone; 2002. p. 31-74.
8. Sushama Desai, Anuya Badwe, Balkrishna Nikam et al. Histopathological study of Interface dermatitis with its clinical correlation. International journal of healthcare & Biomedical research, Volume: 2, Issue: 3 , April 2014 , Pages 24-32
9. Suja Ajoy Kumar, G Nandakumar. A study of Interface Dermatitis with clinical correlation. Journal of Evolution Of Medical and Dental Sciences 2015 ; Vol . 4, Issue 42, May 25; Page: 7344-7351
10. Vijaya Kumar Hegde , Urmila N Khadilkar , A clinicopathological study of interface dermatitis. IOSR Journal of Dental and Medical Sciences (IOSR- JDMS) .2014. Volume 13,
Issue 4 Ver. IV. (Apr. 2014), PP 105-107
2. Le Boit PE. Interface Dermatitis. How specific are its histopathologic features? Arch Dermatol 1993; 129:1324-28
3. Virendra Sehgal, G Srivastava et al. Lichenoid tissue reaction/Interface dermatitis: Recognition, classification, etiology & clinicopathological overtones. Indian Journal of Dermatology ,venerology and Leprology 2011; Vol 77: Issue 4:418-430.
4. Tilly JJ, Drolat BA, Esterley NB et al. Lichenoid eruptions in Children. J Am Acad Dermato;2004;51:606-24.
5. Rajiv Joshi. SYMPOSIUM DERMATOPATHOLOGY. Indian Journal of Dermatology, Venereology & Leprology 2013;79:3: 349-59.
6. Philip Le boit. Dermatitis involving dermo-epidermal junction. In:Maize JC. Burgdorf WH, Hurt MA, Le Boit PE, Metcalf JS, Smith T et al, editors. Cutaneous Pathology. Philadelphia: Churchill Livingstone:1998.pg 87-145.
7. Weedon D. The Lichenoid Reaction Pattern. In: Weedon D, editor. Skin Pathology. 2 nd ed. New York: Churchill Livingstone; 2002. p. 31-74.
8. Sushama Desai, Anuya Badwe, Balkrishna Nikam et al. Histopathological study of Interface dermatitis with its clinical correlation. International journal of healthcare & Biomedical research, Volume: 2, Issue: 3 , April 2014 , Pages 24-32
9. Suja Ajoy Kumar, G Nandakumar. A study of Interface Dermatitis with clinical correlation. Journal of Evolution Of Medical and Dental Sciences 2015 ; Vol . 4, Issue 42, May 25; Page: 7344-7351
10. Vijaya Kumar Hegde , Urmila N Khadilkar , A clinicopathological study of interface dermatitis. IOSR Journal of Dental and Medical Sciences (IOSR- JDMS) .2014. Volume 13,
Issue 4 Ver. IV. (Apr. 2014), PP 105-107
Published
2017-04-21
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