Primary Epithelioid Sarcoma of Forearm with Axillary Lymphnode Metastasis: A Rare case report
Keywords:
Epithelioid sarcoma, Malignant mesenchymal tumour, Squamous cell carcinoma, Fine Needle Aspiration Cytology
Abstract
Primary epithelioid sarcoma is a rare, slow growing malignant mesenchymal tumour, which may mimics a benign granulomatous lesion clinically and cytologically, leading to misdiagnosis. This is typically present as a subcutaneous or deep dermal mass in distal portions of the extremities with strong propensity for local recurrence and metastasis. Cytologically it is very challenging to diagnose epithelioid sarcoma as it may mimics synovial sarcoma, malignant melanoma, squamous cell carcinoma and epithelioid angiosarcoma. In this report we are describing the cytological features of epithelioid sarcoma with emphasizing on FNAC as the first line of investigation.References
1. Enzinger FM. Epithelioid sarcoma: a sarcoma simulating a granuloma or a carcinoma. Cancer. 1970,26:1029-41.
2. Barwad A, Dey P, Das A. Fine needle aspiration cytology of epithelioid sarcoma. Diagn Cytopathol 2011;39:517-20.
3. Willen H, Akerman M, Carlen B. Fine needle aspiration (FNA) in the diagnosis of soft tissue tumours; a review of 22 years experience. Cytopathology 1995;6(4):236–47.
4. Chase DR, Enzinger FM. Epithelioid sarcoma. Diagnosis, prognostic indicators, and treatment. Am J Surg Pathol 1985;9:241-63.
5. Prat J, Woodruff JM, Marcove RC. Epithelioid sarcoma: An analysis of 22 cases indicating the prognostic significance of vascular invasion and regional lymph node metastasis. Cancer 1978;41:1472-87.
6. Linscheid RL. Primary epithelioid sarcoma of the hand and forearm- a review of thirteen cases. J Bone Joint Surg 1974; 56:458-65.
7. Willén H, Akerman M, Carlén B. Fine needle aspiration (FNA) in the diagnosis of soft tissue tumours; a review of 22 years experience. Cytopathology 1995;6:236-47.
8. Lemos MM, Chaves P, Mendonça ME. Is preoperative cytologic diagnosis of epithelioid sarcoma possible? Diagn Cytopathol 2008;36:780-6.
9. Cardillo M, Zakowski MF, Lin O. Fine-needle aspiration of epithelioid sarcoma: Cytology findings in nine cases. Cancer 2001;93:246-51.
10. Niemann TH, Bottles K. Cytologic diagnosis of metastatic epithelioid sarcoma. A cytologic mimic of squamous cell carcinoma. Am J Clin Pathol 1993;100(2):171–3.
2. Barwad A, Dey P, Das A. Fine needle aspiration cytology of epithelioid sarcoma. Diagn Cytopathol 2011;39:517-20.
3. Willen H, Akerman M, Carlen B. Fine needle aspiration (FNA) in the diagnosis of soft tissue tumours; a review of 22 years experience. Cytopathology 1995;6(4):236–47.
4. Chase DR, Enzinger FM. Epithelioid sarcoma. Diagnosis, prognostic indicators, and treatment. Am J Surg Pathol 1985;9:241-63.
5. Prat J, Woodruff JM, Marcove RC. Epithelioid sarcoma: An analysis of 22 cases indicating the prognostic significance of vascular invasion and regional lymph node metastasis. Cancer 1978;41:1472-87.
6. Linscheid RL. Primary epithelioid sarcoma of the hand and forearm- a review of thirteen cases. J Bone Joint Surg 1974; 56:458-65.
7. Willén H, Akerman M, Carlén B. Fine needle aspiration (FNA) in the diagnosis of soft tissue tumours; a review of 22 years experience. Cytopathology 1995;6:236-47.
8. Lemos MM, Chaves P, Mendonça ME. Is preoperative cytologic diagnosis of epithelioid sarcoma possible? Diagn Cytopathol 2008;36:780-6.
9. Cardillo M, Zakowski MF, Lin O. Fine-needle aspiration of epithelioid sarcoma: Cytology findings in nine cases. Cancer 2001;93:246-51.
10. Niemann TH, Bottles K. Cytologic diagnosis of metastatic epithelioid sarcoma. A cytologic mimic of squamous cell carcinoma. Am J Clin Pathol 1993;100(2):171–3.
Published
2015-10-25
Issue
Section
Case Reports
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