Mediastinum: A Pandora’s Box: a study of mediastinal lesions at tertiary hospital of South Canara.
Keywords:
mediastinum, thymoma, myasthenia gravis, filariasis
Abstract
Although the mediastinum is a relatively small anatomic compartment, the diversity of pathologic processes that may reside in it is impressive. Such lesions are both nonneoplastic and neoplastic, and they include proliferations of somatic epithelial, lymphoid and mesenchymal cell types. A retrospective review was undertaken of all cases of mediastinal lesions that presented to the Department of Pathology of K . S. Hegde Medical Academy, Deralakatte, Mangalore, over a 5-year period i.e from 2010 to 2015. 22 mediastinal mass lesions were managed over the period of the review. Thymoma was the most common pathology, being present in 6 (27.2%) cases. A variety of other pathologies were encountered, including neurofibroma , teratoma, thymic cyst , retrosternal goitre , Kimura’s disease and thymic hyperplasia . Patients usually were symptomatic . Chest pain and discomfort was most common symptom, others were dyspnea and cough. MRI has become a useful tool for providing supplemental data in combination with CT. Prompt thoracic surgical referral with view to aggressive, early resection optimizes clinical outcome in the short and medium-term for patients presenting with mass lesions of the mediastinum.References
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2. Rosai J. Rosai and Ackerman’s Surgical Pathology. 10th edition. Mosby. 2011.472.
3. Vaziri M, Pazooki A, Shoolami LZ. Mediastinal Masses: Review of 105 Cases. Acta Medica Iranica 2009;47(4):297-300.
4. Permi HS, Samaga BN, Subramanyam K, Shetty JS, Teerthnath S, Baikunje V et al. Microfilaria in pericardial effusion coexisting with spindle cell thymoma - a rare case report. NUJHS December 2011;1:40-2.
5. Cohen AJ, Thompson LN, Edwards FH, Bellamy RF. Primarv Cvsts and Tumors of the Mediastinum. Ann Thorac Surg.1991;51:378-86.
6. Lewis JE, Wick MR, Scheithauer BW, Bernatz PE, Taylor WF. Thymoma. A clinicopathologic review. Cancer December 1987;60(11):2727-43.
7. Temes R. Primary Mediastinal Malignancies:Findings in 219 Patients. WJM March 1999;170(3):161-6.
Published
2016-04-27
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Original Article
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