Clinical presentation of dengue outbreak 2015, Haryana, India: a prospective observational study
Keywords:
Dengue, Classical Dengue fever, Dengue Haemorrhagic Fever, Dengue Shock Syndrome
Abstract
Background: Dengue fever is not recognized as a major public health hazard in Delhi and neighbouring areas as Haryana, so there is little evidence and awareness in this regard. A prospective observational study was carried out to determine the group of patients suffering from dengue syndrome; clinical parameters of the subjects for hospitalization and the pattern of presentation of dengue fever in a tertiary care centre of the state from September 2015 to November 2015. Method: Total 400 serologically positive cases were selected randomly and diagnosed clinically as dengue, and were classified into 3 groups, i.e. 260 cases of classical dengue fever, 120 cases of dengue hemorrhagic fever(DHF) and 20 cases of dengue shock syndrome (DSS).Results : Classical type of Dengue fever was the commonest (65%) variety. 258(64.5%) were males and 142(35.5%) were females. DHF/DSS were present in adult population (29 yrs). 50.5% of patients had low grade fever of 99˚-100˚F. Diarrhea and abdominal pain were chief complaints in 33.3% cases in group -2. 33.3 % patients of group-2 and 50% of group-3 patients had gum bleeding. 40 patients were diagnosed with acute cholecystitis on ultrasonography. Ascitis with bilateral pleural effusion was a common finding in 95% of the patients of group-2 with platelet counts of <20000. Mortality rate was less than 1%.Conclusion: Results of our study indicate that apart from usual manifestations, sometimes unusual but clinically extremely important manifestations can occur which if not detected early can prove fatal requiring vigilant approach.References
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Infection Is Endemic. J Clin Microbiol 2007; 45(5): 1523-27.
2. Ahmedul Kabir. et.al The impact of dengue on liver function as evaluated by aminotransferase levels. J Medicine 2008; 9 : 66-68.
3. World Health Organization. Dengue haemorrhagic fever: diagnosis, treatment, prevention and control, 2nd edn. Geneva: WHO, 1997.
4. P. Ggunasekaran .et al. Dengue disease status in Chennai (2006-2008): A retrospective analysis. Indian J.Med Res 2011;133:322-25
5. Smith CEG. The history of dengue in tropical Asia and its probable relationship to the mosquito Aedes aegypti. Trop Med Hyg 1956; 243±51
6. Ashish Goel et.al Dengue fever- A dangerous Foe. J Indian Academy of Clinical Medicine 2004;5(3):247-58
7. Anuradha S et.alThe 1996 outbreak of dengue hemorrhagic fever in Delhi, India. South Asian JTrop Med Public Health 1998;29(3):503-6
8. Wali J.P et al. Dengue hemorrhagic fever in adults: a perspective syudy of 110 cases. Trop. Doct. 1999; 29(1):27-30
9. Singh N.P et.al The 2003 outbreak of dengue fever in Delhi, India. South East Asian J Trop Med Public Health 2005; 36(5) :1174-8
10. Jhamb R, Kumat A, Ranga GS, Rathi N. Unusual manifestations in dengue outbreak 2009, Delhi,India. J Commun Dis. 2010 Dec:42 (4):255-61
11. World Health Organization. Dengue haemorrhagic fever: diagnosis, treatment, prevention and control, 2nd edn. Geneva: WHO, 1997.
12. Chareonsook O, Foy HM, Teeraratkul A, Silarug N. Changing epidemiology of dengue haemorrhagic fever in Thailand. Epidemiol infect 1999; 122: 161-6.
13. Kabra SK, Jain Y, Pandey RM, Singhal T, Tripathi P, Broor S, et al. Dengue haemorrhagic fever in children in the 1996 Delhi epidemic. Trans Royal Soc Trop Med Hyg 1999; 93: 294-8.
14. Sai PMV, Dev B, Krishnan R. Role of ultrasound in dengue fever. British J Radiol 2005; 78:416-418.
15. David IW, A case of fatal plasmodium falciparum malaria complicated by acute dengue fever in East Timor. Am J Trop Med Hyg 2006;75(1):182-185.
16. Shah I, Deshpande GC, Tardeja PN, Outbreak of dengue in Mumbai and predictive markers for dengue shock syndrome. J Trop Pediatr. 2004 Oct;50(5):301-5.
17. Zuckerman AJ, Banatvala JE, Pattison JR, Griffiths PP, Schoub BD, editors. Principles and practice of clinical virology. 5th ed. West Sussex, England: John Wiley & Sons, Ltd; 2004.
18. Gregson A, Edelman R. Dengue virus infection. Pediatr Infect Dis J. 2003;22:179–81.[PubMed]
Published
2016-05-26
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