Osteosarcoma of the talus: A rare location of the tumour with literature
Keywords:
Osteosarcoma, Primary Malignant Bone Tumor, Talus, Giant Cell Tumour
Abstract
Osteosarcoma is the commonest primary malignant bone tumor. Most of them arises de novo in the metaphyseal area of the long bones. Osteosarcoma arising distal to the wrist or ankle is extremely rare and most often secondary to a premalignant process such as Paget disease. We reported a rare case of conventional osteosarcoma of the talus. A 40-year-old lady presented with painless left foot swelling for the past two years with gradually increasing in size within 6 months. Tru-cut tissue biopsy was reported as giant cell tumour. However histopathology of resected talus bone revealed that tumour was conventional osteosarcoma with focal features of giant cell rich osteosarcoma.References
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2. Fechner R.E; Mills S.E. In: Osseous Lesions. Atlas of Tumor Pathology: Tumors of the Bones and Joints. Washington D.C: Arm Forces Institute of Pathology, 1993. pp 25-77.
3. Choong PFM, Qureshi AA, Sim FH, Unni K.K. Osteosarcoma of the foot: A review of 52 patients at the Mayo Clinic. ActaOrthopScand 1999; 70:361-4.
4. Anninga JK, Picci P, Fiocco M, Kroon HM, Vanel D, Alberghini M, et al. Osteosarcoma of the hands and feet: a distinct clinico-pathological subgroup. Virchows Arch 2013; 462:109-20.
5. Biscaglia R, Gasbarrini A, Böhling T et al. Osteosarcoma of the bones of the foot. An easily misdiagnosed malignant tumor. Mayo Clin Proc1998; 73:842-7.
6. Chou LB, Ho YY, Malawer MM. Tumors of the foot and ankle: experience with 153 cases. Foot Ankle Int 2009; 30:836-41.
7. Ellison BS, Potter M, Morrison C, Mayerson J. Talar osteosarcoma in an elderly woman. Am J Orthop (Belle Mead NJ) 2008; 37:198-203.
8. Chaudhary S, Singh D, Sen R, Deviraju C, Bhagwat K. Osteosarcoma of calcaneum, A case series of rare tumour presenting a diagnostic dilemma. WebmedCentral ORTHOPAEDICS 2010; 1(12):WMC001273.
9. Lu Q, Lv G, Kim A, Ha J-M, Kim S. Expression and clinical significance of extracellular matrix metalloproteinase inducer, EMMPRIN/CD147, in human osteosarcoma. Oncology Letters. 2013;5(1):201-207.
10. Yu X, Kong W, Zheng K. Expression of osteoprotegerin and osteoprotegerin ligand in giant cell tumor of bone and its clinical significance. Oncology Letters. 2013; 5(4):1133-1139.
Published
2016-12-11
Section
Case Report
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