Incidence of Eosinophilia in Rural Population in North India: A Study at Tertiary Care Hospital

  • Rimpi Bansal GIAN SAGAR MEDICAL COLLEGE AND HOSPITAL
  • Anureet Kaur GIAN SAGAR MEDICAL COLLEGE AND HOSPITAL
  • Anil K Suri GIAN SAGAR MEDICAL COLLEGE AND HOSPITAL
  • Puneet Kaur GIAN SAGAR MEDICAL COLLEGE AND HOSPITAL
  • Monika Bansal GIAN SAGAR MEDICAL COLLEGE AND HOSPITAL
  • Rupinderjeet Kaur GIAN SAGAR MEDICAL COLLEGE AND HOSPITAL
Keywords: Eosinophilia, Allergy, Atopy, Punjab

Abstract

BACKGROUND- Eosinophilia is abnormally high number of eosinophils in the blood. Normally, eosinophils constitute 1 to 6% of the peripheral blood leukocytes, at a count of 350 to 650 per cubic millimeter. Eosinophilia can be categorized as mild (less than 1500 eosinophils per cubic millimeter), moderate (1500 to 5000 per cubic millimeter), or severe (more than 5000 per cubic millimeter). Eosinophilia may be primary or secondary. The aim of the study was to determine the incidence of eosinophilia and evaluate the patients thoroughly for the cause of eosinophilia.METHOD- The study was conducted in the Pathology department in the medical college and hospital in rural are of Punjab. Complete blood count and peripheral blood film study was done in almost all the patients visiting the hospital. The patients with eosinophilia were segregated and were made to fill the detailed proforma. The information included family history, chief complaints, food habits, disease history  and drug history. A thorough general examination and diagnostic work up followed. RESULT- In all 3442 (10.7%) patients visiting the hospital had eosinophilia; out of this 2136 (62%) patients had mild eosinophilia, 1297 (37.7%) had moderate and 9 (0.3%) had severe eosinophilia. 2451(71.2%) patients were males and 991 (28.8%) were females. Age group of patients varied from 3 yrs to 74 yrs. The chief complaints of our patients were related to  fever, cough, rashes, breathlessness, wheezing etc.  other major group of patients had symptoms of abdominal pain, diarrhea, pallor, pica and loss of appetite.CONCLUSION- Eosinophilia appears to be a common occurrence in the in the rural population around our hospital. The most common etiologies were due to parasitic, protozoal or fungal  infestations and infections. Allergy related problem also constituted a significant health problem in the local population. DOI: 10.21276/apalm.2017.1044

Author Biography

Rimpi Bansal, GIAN SAGAR MEDICAL COLLEGE AND HOSPITAL
PROFESSOR,PATHOLOGY

References

1. Valent P, Klion AD, Rosenwasser LJ et al. ICON: Eosinophil Disorders. The World Allergy Organization Journal 2012;5(12):174-181.
2. Nutman TB. Asymptomatic peripheral blood eosinophilia redux: Common parasitic infections presenting frequently in refugees and immigrants. Clin Infect Dis 2006;42(3): 368-369.
3. Webb JKG.. Etiology of tropical eosinophilia. Indian Journal of Tuberculosis 1961;8 (3):95-98.
4. Udwadia FE. Tropical eosinophilia. In:Herzog H. Pulmonary eosinophilia: Progress in respiration research. 7th ed. Basel. Karger 1975:35-155.
5. Turnbull LW, Evans DP, Kay AB: Human eosinophils, acidic tetrapeptides(ECF-A) and histamine. Interactions in vitro and in vivo. Immunology 1977;32:57-68.
6. Samuel AM, Udwadia FE, Parab PB et al. Cell mediated and humoral immune response in tropical eosinophilia. Indian Journal of Medical Research 1978;68:444-449.
7. Dacie YV, Lewis SM. Basic hematologic techniques. Practical Hematology, 7th ed. Edinburg: Churchill Livingstone 1991:37-68.
8. Epstein FH. Eosinophilia. N Engl J Med 1998;338:1592-1600.
9. Knopp S, Mgeni AF, Khamis IS et al. Diagnosis of soil-transmitted helminths in the era of preventive chemotherapy: effect of multiple stool sampling and use of different diagnostic techniques. PLoS Negl Trop Dis 2008;2(11):331.
10. Glass D, Amedee RG. Allergic fungal rhinosinusitis: a review. Ochsner J 2011; 11(3):271-275.
11. Mori A, Enweluzo C, Grier D et al. Badireddy M. Eosinophilic gastroenteritis: Review of a rare and treatable disease of the gastrointestinal tract. Case Reports in Gastroenterology 2013;7(2):293-298.
12. Mullerpattan JB, Udwadia ZF, Udwadia FE. Tropical pulmonary eosinophilia - A review. The Indian Journal of Medical Research 2013;138(3):295-302.
13. Haider S, Farhangi M. Hypereosinophilic Syndrome. Indian Journal of Practicing Doctors 2005;2(3):
14. Weller PF. Eosinophilic syndromes. In: Goldman L, Bennett JC, eds. Cecil Textbook of Medicine., 25th Ed. Philadelphia: W.B. Saunders 2000:1151-1154
Published
2017-02-03
Section
Original Article