Seroprevalence of Hepatitis B Surface Antigen positive Patients Attending a Tertiary Care Hospital in Srikakulam, Andhra Pradesh.

  • Aruna Bula RAJIV GANDHI INSTITUTE OF MEDICAL SCIENCES(RIMS),SRIKAKULAM,ANDHRA PRADESH
  • Santhosh Ram Gaddam ANDHRA MEDICAL COLLEGE,VISAKHAPATNAM,ANDHRA PRADESH
Keywords: Hepatitis B, HBsAg, Prevalence, Srikakulam.

Abstract

Background: Hepatitis B virus (HBV) infection continues to be a serious public health problem globally and studying the prevalence of HBV infection in a geographical area aids in establishing magnitude of the problem. A teaching hospital based population study of Hepatitis B surface antigen (HBsAg) is a strong indicator of true HBV infection rate in the community as large number of patients from different backgrounds attend the hospital.Methods: A one step rapid immunochromatographic method for detection of HBsAg was performed to diagnose HBV infection. 24,028 sera samples were tested over a period of one year 9 months.Result: Out of the 24,028 samples tested for HBsAg, 733 (3.05%) were found to be positive for HBsAg. Positivity rate was more among males 440 (60.02 %) than females 293 (39.97 %) and the most common age group in males was 41-50 years (23.18 %) followed by 31- 40 years (22%).In females, commonest age group was 21-30 years (38.22%) followed by 31-40 years (14.67 %).Conclusion: The study helps to know the magnitude of viral transmission in the community & to know the at risk age groups.Seroprevalence of HBsAg in Srikakulam, Andhra Pradesh was found to be 3.05% which is in accordance with the national average of 2-7 % and it falls into intermediate zone of  HBsAg prevalence according to WHO. DOI: 10.21276/APALM.2017.1118 

Author Biographies

Aruna Bula, RAJIV GANDHI INSTITUTE OF MEDICAL SCIENCES(RIMS),SRIKAKULAM,ANDHRA PRADESH
ASSISTANT PROFESSOR,DEPARTMENT OF MICROBIOLOGY
Santhosh Ram Gaddam, ANDHRA MEDICAL COLLEGE,VISAKHAPATNAM,ANDHRA PRADESH
SENIOR RESIDENT,DEPARTMENT OF ORTHOPAEDICS

References

1. Quadri SA, Dadapeer HJ, Arifulla KM, Khan N. Prevalence of Hepatitis B Surface Antigen in hospital based population in Bijapur,Karnataka. Al Ameen J Med Sci 2013;6(2):180-182.

2. Sood S. Serological Evaluation of Hepatitis B Virus in out patient Department patients of a private Hospital in North –West India. National J of Community Medicine, 2013:4;485-488.

3. Naqshbandi I, Quadri SYA, Yasmeen N, Bashir N. Seroprevalence and Risk Factors of Hepatitis B virus Infection among General Population of Srinagar Kashmir.Int.J of Contem Med Res 2016;3 (4):1050-1054.

4. Sood S, Malvankar S. Seroprevalence of Hepatitis B Surface Antigen,Antibodies to the Hepatitis C Virus,and Human Immunodeficiency Virus in a Hospital-Based Population in Jaipur,Rajasthan.Indian J Community Med.2010;35 (1):165-169.

5. Wu JF, Chang MH. Natural history of chronic hepatitis B virus infection from infancy to adult life-the mechanism of inflammation triggering and longterm impacts.J. BioMed Sci.2015;22:92: 1-7.

6 . Ananthanarayana R, Paniker CKJ, Text book of Microbiology, Universities Press(India) Private Limited 2003,9 th ed, pg:543-545.

7. Ocama P, Opio CK, Lee WM. HepatitisB virus infection: Current status. The American J Med. 2005;118,1413.e15-1413.e22.

8. Patel PA, Patel SP, Oza HV. Seroprevalence of Transfusion Transmitted Infections(TTIs) in Blood Donors at Western Ahmedabad-A secondary care Hospital Based Study.Int J Biol Med Res.2012;3(2): 1806-1810.

9. Supekar SN, Patel HL .Prevalence of Hepatitis B virus Infection in Young Students of Anand. Nat J Med Res 2012; 2(3):299-301.

10. Saraswathi KS, Aljabri F. The study of prevalence of Hepatitis B surface antigen during pregnancy in a tertiary care hospital,South India. Der Pharmacia Lettre, 2012,4(3):983-985.

11. Khaleel M, Syed A. Comparative study on Prevalence of Hepatitis B surface antigen among blood donors and in patient hospital attendees at a tertiary care hospital, Hyderabad. Ind J Bas Appl Med Resear 2016,5 (3):280-284.

12. Samatha P, Sireesha DM, Sowmya BS. Seroprevalence of Hepatitis B surface antigen , Antibodies to Hepatitis C&HIV in a hospital based population.J Biosci Tech 2015,6 (1):597-601.

13.Singh J, Bhatia R, Khare S, Patnaik SK ,Biswas S, Lal S et al. Community studies on prevalence of HBsAg in two urban populations of southern India.Ind Paeiatr 2000,37 (2):149-52.

14. Bhawani Y, Rao PR, Sudhakar V. Seroprevalence of transfusion transmissible infections among blood donors in a tertiary care hospital of Andhra Pradesh. Biology and Medicine 2010 ,2 (4):45-48.

15. Chandra M, Khaja MN, Farees N, Poduri CD, Hussain MM, Habeeb M , Habibullah CM. Prevalence, risk factors and genotype distribution of HCV and HBV infection in the tribal population :a community based study in South India. Tropical Gastro 2003,24 (4):193-195.

16. Batham A, Gupta MA, Rastogi P, et al .Calculating Prevalence of Hepatitis B in India: Using Population Weights to look for Publication Bias in Conventional Meta-analysis. Ind J Paed 2009 ;76:1247-1257.
Published
2017-02-23
Section
Original Article