Cyto-Histopathological correlations of Head and Neck swellings in a rural hospital in North Maharashtra: Our experience
Keywords:
Head and Neck, FNAC, Histopathology, Diagnostic
Abstract
Background: The head and neck encompass a relatively small anatomic area. But anatomy and pathology of this region is extremely complex with multitude of congenital, inflammatory or neoplastic lesions. Fine needle aspiration cytology (FNAC) is a simple, feasible, cost effective and minimally invasive procedure. But histopathological examination is more valuable for confirmatory diagnosis in suspected lesions.Aim: 1.To study the diagnostic accuracy of FNAC by comparative study with histopathological examination. 2. To study the spectrum of non-neoplastic and neoplastic lesions of head neck in rural population. Methods: A retrospective research study included 363 patients presented with head and neck swellings in a rural hospital from April 2013 to April 2015. Detailed clinical history of patient was noted. Aspirations were done and smears were stained with PAP, Haematoxylin and eosin and Leishman stain. Cytomorphological diagnosis was given. Cyto-histopathological correlations were done in 205 cases.Result: Out of 363 patients studied, lymph node (39.66%) was the predominant site aspirated followed by thyroid lesions (30.30 %), salivary gland (19.00%), soft tissue and miscellaneous (7.71%). FNAC was inconclusive in 3.30 % cases. A histopathological correlation was done in 56.47% cases. Overall accuracy rate of FNAC was 97.07%. The sensitivity, specificity, positive predictive value, negative predictive value of test was 80.00 %, 98.91 %., 88.88% and 97.86 % respectively.Conclusion: Though, FNAC is a rapid, cheap diagnostic tool now-a-days, excisional biopsy remains the gold standard for diagnosis of suspected or grey zone of head and neck lesions.References
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17. Fernandes H,D’Souza RS,Thejaswini BN. Role of Fine Needle Aspiration Cytology In Palpable Head and Neck Masses.Journal of clinical and diagnostic research 2009;3:1719-25
2. Ahluwalia H, Gupta SC, Singh M, Gupta SC, Mishra V, Singh PA. Spectrum of head and neck cancers at Allahabad.J Otolaryngol Head Neck Surg. 2001;53:16-20.
3. Mehrotra R, Singh M, Gupta RK, Singh M, Kapoor AK. Trends of prevalence and pathological spectrum of head and neck cancers in North India. Indian J Cancer. 2005;42:89-93.
4. El Hag IA, Chiedozi LC, al Reyees FA, Kollur SM. Fine needle aspiration cytology of head and neck masses. Seven years’ experience in a secondary care hospital. Acta Cytol. 2003;47:387–92.
5. Klijanienko J. Head and Neck and Salivary gland.In: Layfield LJ, editor. Atlas of Fine Needle Aspiration Cytology,1st edn.New Delhi:Jaypee Publishers;2014.p.11.
6. Ponder TB, Smith D, Ramzy I. Lymphadenopathy in children and adolescents: role of fine-needle aspiration in management. Cancer Detect Prev. 2000; 24:228–33.
7. Martin HE, Ellis EB. Biopsy of needle puncture and aspiration. Ann Surg. 1930; 92:169-81.
8. Muddegowda PH, Srinivasan S, Lingegowda JB, Ramkumar KR, Murthy KS. Spectrum of Cytology of Neck Lesions: Comparative Study from Two Centers. Journal of Clinical and Diagnostic Research. 2014; Vol-8(3): 44-45.
9.Bhagat VM, Tailor HJ, Saini PK, Dudhat RB, Makawana GR, Unjiya RM. Fine Needle Aspiration Cytology In Nonthyroidal Head And Neck Masses-A Descriptive Study In Tertiary Care Hospital. National Journal Of Medical Research. 2013; volume 3(3):273-76.
10.Mohamed MH, Hitam S, Brito-Mutunayagam S, Yunus MRM. Role of FNAC in evaluation of neck masses. J Curr Surg. 2013;3(1):19-23.
11.Sharma R, Mathur DR. Fine needle aspiration cytology (FNAC) of palpable lesions of head and neck region. Int J Cur Res Rev 2012; Vol 04 (22):74-84.
12. Rathod GB, Parmar P. Fine needle aspiration cytology of swellings of head and neck region. Indian J Med Sci 2012;66:49-54.
13. Ahmad T, Naeem M, Ahmad S, Samad A, Nasir A. Fine needle aspiration cytology (FNAC) and neck swellings in the surgical outpatient. J Ayub Med Coll Abbottabad 2008;20:30-2.
14. Kamal F, NiazI S, Nagi AH, Jaradi MA, Naveed IA. Fine needle aspiration cytology (FNAC): an experience at King Edward Medical College, Lahore.Pak J Pathol 1996;7:33–6.
15. Tilak V, Dhaded AV, Jain Raginiet al : Fine needle aspiration cytology of Head and Neck masses. Indian J Pathol Microbiol 2002; 45(1):23-30.
16. Maniyar AU,Patel HL,Parmar BH.Study of Cytodiagnosis of Head and Neck Neoplastic Lesions and comparision with histopathology.RRJMHS 2013;2(2):54-9.
17. Fernandes H,D’Souza RS,Thejaswini BN. Role of Fine Needle Aspiration Cytology In Palpable Head and Neck Masses.Journal of clinical and diagnostic research 2009;3:1719-25
Published
2015-10-26
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