Tubercular Cervicitis Clinically Mimicking Malignancy: Cytodiagnosis of Two Cases
Keywords:
Genital tuberculosi, Pap smear, Tubercular cervicitis, Genital tract
Abstract
Genital tuberculosis (TB) in females is found in 0.75-1% of gynecological admissions in India with considerable variation from place to place and occurs in 10% cases of pulmonary TB. During colposcopy a bulky, necrotic cervix with parametrial thickening in pelvic TB often elicits an initial diagnostic impression of carcinoma of cervix. As the detection rate of AFB is low, definitive diagnosis of genital TB in females often depends mainly upon the cytological and histopathological examination. Here we describe two cases of cervical TB diagnosed by PAP smear, which showed granulomata consisting of multinucleated giant cells, histiocytes, epithelioid cells, lymphocytes and fibroblasts. Both the cases were clinically suspicious of carcinoma cervix. Diagnosis was confirmed in the first case by other supportive evidence like associated pulmonary TB and therapeutic response to ATT. Histopathology confirmation was done in the second case.References
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2. Schaefer G. Female genital tuberculosis. Clin Obstet Gynecol. 1976; 19:223.
3. Miller JW. Vulval tuberculosis. Tubercle1979; 60:173.
4. Bhambani S, Das DK, Singh V. Cervical tuberculosis with carcinoma in situ: A cytodiagnosis (letter). Acta Cytol. 1985; 29:87.
5. Kobayashi-Kawata T, Haramik C. Tuberculous cervicitis. Acta Cytol. 1978; 22:193.
6. Angrish K, Verma K. Cytologic detection of tuberculosis of uterine cervix. Acta Cytol. 1981; 25:160.
7. Seth A, Kudesia M, Gupta K, Pant L, Mathur A. Cytodiagnosis and pitfalls of genital tuberculosis: A report of two cases. J Cytol. 2011; 28: 141–143.
8. Koller AB. Granulomatous lesions of the cervix uteri in black patients. S Afr Med J. 1975; 49:1228–32.
9. Chong VH, Rajendran N. Tuberculosis peritonitis in Negara Brunei Darussalam. Ann Acad Med Singapore. 2005; 34:548–52.
10. Bilgin T, Karabay A, Dolar E, Develioglu OH. Peritoneal tuberculosis with pelvic abdominal mass, ascites and elevated CA 125 mimicking advanced ovarian carcinoma: a series of 10 cases. Int J Gynecol Cancer. 2001; 11:290–4.
Published
2015-11-01
Issue
Section
Case Report
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