Spectrum of Interface dermatitis : An Observational study'

Vishrabdha Rahul Pawar, Vaibhav Pandurang Mane, Renuka Satish Ashtekar


Inroduction: Major role of a dermatopathologists is to try to make specific diagnosis of inflammatory skin diseases. IFD means inflammatory infiltrate that abuts or obscures the dermo-epidermal junction in askin biopsy.This type of reaction is also seen in skin disorders associated with systemic illness like LE and skin changes of potentially fatal disorders such as Graft versus host disease, S-J syndrome and toxic epidermal necrolysis. Aims & Objectives- 1)To study the histopathology of interface dermatitis.(2)To study the common types of skin manifestations  in interface dermatitis.(3)To determine other histological features associated with interface dermatitis.4)To identify the clinical concordance of various types of interface dermatitis.

Methods : Present study is a retrospective , Hospital based study. Ethical consideration was taken. Study duration was Jan 2012 to Dec 2015.

Results: In the present study, a total of 121 cases of IFD were studied, the majority of which [65] presented as papulo- squamous [ papules and plaques ] lesions. Of theses 121 cases, the most common type of IFD was LP and its variants (53.71 %).The next common was LDE (8.26 %) followed by PL(7.4% ). The least common was LN (0.8  % ) and dermatomyositis (1.6 %). Female preponderance was noted in case of IFD [ 59.9 % ]. The percentage of clinical concordance was good in cases  of  LP & its variants (90.77 %), DLE ( 83.33%) and in Dermatomyositis.

Conclusion- A good clinicopathologic correlation is absolutely essential for the final diagnosis of IFD.


DOI: 10.21276/AABS.1460


Interface, Dermatitis, Lichen

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