Fnac of Rosai - Dorfman Disease - Report of 5 Cases
Keywords:
Rosai-Dorfman disease, Lymphadenopathy, FNAC, Giemsa stain, Papanicolaou stain
Abstract
Sinus histiocytosis with massive lymphadenopathy (SHML) is a rare non malignant histiocytic proliferative disorder of unknown etiology presenting with massive lymphadenopathy. These cases can often be misdiagnosed as lymphoma.Very few cases has been diagnosed on FNAC. Here we report 5 cases of Rosai – Dorfman disease presenting with massive bilateral cervical lymphadenopathy. Hence FNAC is a useful and reliable tool for the diagnosis of Rosai-Dorfman disease due to which biopsy can be avoided in these patients.References
1. Juskevicius R, and Finlay JL. Rosai-Dorfman disease of parotid gland, cytologic and histopathologic findings with immunohistochemical correlation. Arch Pathol Lab Med 2001; 125: 1348-1350.
2. Lauwer GY, Perez-Atayde A, Dorfman RF, et al. The digestive system manifestations of Rosai- Dorfman disease (sinus histiocytosis with massive lymphadenopathy): review of 11 cases. Hum Pathol 2000; 31:380-385.
3. Kumar B, Karki S, Paudyal P. Diagnosis of sinus histiocytosis with massive lymphadenopathy ( Rosai- Dorfman disease) by fine needle aspiration cytology. Diagn Cytopathol 2008; 36:691-5.
4. Jinyung Ju, Yong Soon Kwon, Kae Jung Jo et al. Sinus Histiocytosis with massive lymphadenopathy; A Case Report with Pleural Effusion and Cervical Lymphadenopathy. J Korean Med Sci 2009; 24:760-762.
5. Lampert F, Lennert K. Sinus Histiocytosis with massive lymphadenopathy: Fifteen new cases. Cancer 1976; 37:783-9.
6. Detombes P. Adenitis with lipid excess in children or young adults seen in Antilles and in Mali( 4 cases). Bull Soc Pathol ExotFiliales 1965; 58: 1169-75.
7. Rosai J, Dorfman RF. Sinus Histiocytosis with massive lymphadenopathy. Arch Pathol 1969;87:63-7.
8. Sujata G. Multifocal, Extranodal Sinus Histiocytosis With Massive Lymphadenopathy. An Overview. Arch Pathol Lab Med 2007;131: 1117-1121.
9. Das DK, Gulati A, Bhatt NC, Sethi GR. Sinus Histiocytosis with massive lymphadenopathy (Rosai- Dorfman disease): report of two cases with fine needle aspiration cytology. Diagn Cyto Pathol 2001;24:42-45.
10. Kushwaha R, Ahluwalia C, Sipayya K. Diagnosis of sinus histiocytosis with massive lymphadenopathy ( Rosai- Dorfman disease) by fine needle aspiration cytology. Journal of Cytology 2009;26:83-85.
11. Deshpande AH, Nayak S, Munshi MM. Cytology of sinus histiocytosis with massive lymphadenopathy ( Rosai- Dorfman disease). Diagn Cyto Pathol 2000;22:181-5.
2. Lauwer GY, Perez-Atayde A, Dorfman RF, et al. The digestive system manifestations of Rosai- Dorfman disease (sinus histiocytosis with massive lymphadenopathy): review of 11 cases. Hum Pathol 2000; 31:380-385.
3. Kumar B, Karki S, Paudyal P. Diagnosis of sinus histiocytosis with massive lymphadenopathy ( Rosai- Dorfman disease) by fine needle aspiration cytology. Diagn Cytopathol 2008; 36:691-5.
4. Jinyung Ju, Yong Soon Kwon, Kae Jung Jo et al. Sinus Histiocytosis with massive lymphadenopathy; A Case Report with Pleural Effusion and Cervical Lymphadenopathy. J Korean Med Sci 2009; 24:760-762.
5. Lampert F, Lennert K. Sinus Histiocytosis with massive lymphadenopathy: Fifteen new cases. Cancer 1976; 37:783-9.
6. Detombes P. Adenitis with lipid excess in children or young adults seen in Antilles and in Mali( 4 cases). Bull Soc Pathol ExotFiliales 1965; 58: 1169-75.
7. Rosai J, Dorfman RF. Sinus Histiocytosis with massive lymphadenopathy. Arch Pathol 1969;87:63-7.
8. Sujata G. Multifocal, Extranodal Sinus Histiocytosis With Massive Lymphadenopathy. An Overview. Arch Pathol Lab Med 2007;131: 1117-1121.
9. Das DK, Gulati A, Bhatt NC, Sethi GR. Sinus Histiocytosis with massive lymphadenopathy (Rosai- Dorfman disease): report of two cases with fine needle aspiration cytology. Diagn Cyto Pathol 2001;24:42-45.
10. Kushwaha R, Ahluwalia C, Sipayya K. Diagnosis of sinus histiocytosis with massive lymphadenopathy ( Rosai- Dorfman disease) by fine needle aspiration cytology. Journal of Cytology 2009;26:83-85.
11. Deshpande AH, Nayak S, Munshi MM. Cytology of sinus histiocytosis with massive lymphadenopathy ( Rosai- Dorfman disease). Diagn Cyto Pathol 2000;22:181-5.
Published
2018-06-24
Issue
Section
Case Reports
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