Steroid Cell Tumor: A Rare Ovarian Tumor

  • Aastha Raheja
  • Deepti Goswami
  • Pooja Sakhija
  • Gauri Gandhi
  • Bidhisha Singhla
Keywords: Steroid Cell Tumor, Ovarian Tumor, Stromal Tumor, Hyperandrogenism

Abstract

Ovarian steroid cell tumors are sex-cord stromal tumors that arise from lutein cells or leydig cells. These are very rare- accounting for<0.1% of all ovarian tumors.. Some of these tumors may be functional and secrete hormones. Nearly 56-77% of the cases present withhyperandrogenism. Rarely steroid cell tumors may arise in the adrenal cortex from the adrenal rest cellsWe report a case of a 60-year old lady who presented with gradual onset abdominal distension for two years. She had no other complains andhad undergone hysterectomy 20 years back. Her abdomen was over distended due to a large, tense cystic, non-tender mass. Imaging studiesrevealed a large, mainly cystic abdominopelvic mass; however its origin could not be made out. The left adrenal gland was found to be bulkybut morphologically normal. Serum DHEAS levels were normal thus ruling out adrenal pathology. Serum levels of CA 125 and CEA were alsonormal. Exploratory laparotomy was done. A large thin walled cyst occupied the pelvis and abdomen. . It measured 25x20x16cm and contained4.2 litre of straw colored fluid. The fluid was drained and the entire cyst wall was excised. Ovaries were not visualized. Frozen section report ofthe cyst wall was suggestive of a neuroendocrine tumor. Final histopathology report was of benign steroid cell tumor not otherwise specified.In view of the benign nature of ovarian pathology, no further intervention was required. The patient had an uneventful postoperative recover.

Author Biographies

Aastha Raheja
Obstetrics and Gynecology, Department of Obstetrics& Gynecology, Maulana Azad Medical College
Deepti Goswami
Department of Pathology, GB PANT Hospital, New Delhi
Pooja Sakhija
Department of Pathology, GB PANT Hospital, New Delhi
Gauri Gandhi
Department of Obstetrics& Gynecology, Maulana Azad Medical College, New Delhi
Bidhisha Singhla
Department of Obstetrics& Gynecology, Maulana Azad Medical College, New Delhi

References

1. Hayes MC, Scully RE: Ovarian steroid cell tumors (not otherwise specified):a clinicopathological analysis of 63 cases. Am J Surg Pathol 1987,11:835–845.
2. Outwater EK, Wagner BJ, Mannion C, McLarney JK, Kim B: Sex cord-stromal and steroid cell tumors of the ovary. Radiographics 1998, 18:1523–1546
3. Liu AX, SunJ, Song WQ: Steroid cell tumors, not otherwise specified, in an accessory ovary: a case report and literature review. Gynecol Oncol 2005, 97:260–262.
Published
2018-06-08
Section
Case Reports