Androgen Insensitivity Syndrome (Testicular Feminization) – A Retrospective Diagnosis: Case Report

  • Ankur Singh
  • Soniya Tanwar
  • Vandana Porwal
  • Neena Kasliwal
Keywords: Testicular feminization, androgen insensitivity, retrospective

Abstract

Testicular feminization, or the androgen insensitivity syndrome, is a rare disease. It occurs due to various abnormalities of the X chromosome, a male, genetically XY, has some physical characteristics of a female or a full female phenotype. The androgen insensitivity syndrome occurs because of a resistance to the actions of the androgen hormones, which in turn switches the development towards the aspect of a female. We report a retrospectively diagnosed case of complete androgen insensitivity syndrome in a 50 years old woman who presented with right inguinal swelling. We aim to improve our knowledge of this illness from the data that provides us this study.

Author Biographies

Ankur Singh
Department of Pathology, Jawahar Lal Nehru Medical College, Ajmer (Rajasthan)
Soniya Tanwar
Department of Pathology, Jawahar Lal Nehru Medical College, Ajmer (Rajasthan)
Vandana Porwal
Department of Pathology, Jawahar Lal Nehru Medical College, Ajmer (Rajasthan)
Neena Kasliwal
Department of Pathology, Jawahar Lal Nehru Medical College, Ajmer (Rajasthan)

References

Sharma S, Balwan WK, Kumar P, Gupta S. Androgen Insensitivity Syndrome (Testicular Feminization). J Obstet Gynaecol India 2012;62(2):199-201.

Constantin G, Alexandru D, Sorin P, Liliana D, Mihaela M, Mihai H et al. Testicular feminization: complete androgen insensitivity syndrome. Discussions based on a case report. Rom J Morphol Embryol 2014;55(1):177-81.

Bhat G, Raviraj MB, Jayaram S, Siddalingaiah I, Huchappa NN. Androgen Insensitivity Syndrome: Case report with review of literature. UroToday Int J.2011 Jun;4(3):art 33.

Published
2021-06-29
Section
Case Reports