Giant Cell Lesion and Central Giant Cell Granuloma of Jaw: A Brief Review
Keywords:
Craniofacial, Oral pathology, Intraosseous lesion
Abstract
This review discusses giant cell lesion with main focus on central giant cell granuloma of jaw. Review of the lesion with regard to its nomenclature, pathogenesis and its clinical, radiological & histopathological features is presented. Surgical therapy along with recently reported conservative management protocol is discussed in detail. DOI: 10.21276/AABS.2017.1315References
1. Edwards PC, Fox J, Fantasia JE, Goldberg J, Kelsch RD. Bilateral central giant cell granulomas of the mandible in an 8-year-old girl with Noonan syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;99:334-40
2. De Lange J, Van den Akker HP. Clinical and radiological features of central giant-cell lesions of the jaw. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;99:464-70
3. Kruse-Lösler B, Diallo R, Gaertner C, Mischke KL, Joos U, Kleinheinz J. Central giant cell granuloma of the jaws: A clinical, radiologic, and histopathologic study of 26 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:346-54
4. Ciorba A, Altissimi G, Giansanti M. Giant cell granuloma of the maxilla: case report. Acta otorhinolaryngol Ital 24, 26-29, 2004
5. De Lange J, Van den Akker HP. Radiologic features of central giant cell granuloma of the jaw. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996;81:720-6
6. Sidhu MS, Parkash H, Sidhu SS. Central giant cell granuloma of jaws-review of 19 cases. Br J Oral Maxillofac Surg. 1995 Feb;33(1):43-6.
7. Stavropoulos F, Katz J.Central giant cell granulomas: A systematic review of the radiographic characteristics with the addition of 20 new cases. Dentomaxillofac Radiol. 2002 Jul;31(4):213-7.
8. Bataineh AB, Al-Khateeb T, Rawashdeh MA. The Surgical Treatment of Central Giant Cell Granuloma of the Mandible. J Oral Maxillofac Surg. 2002 Jul;60(7):756-61.
9. Rawashdeh MA, Bataineh AB, Al-Khateeb T. Long-term clinical and radiological outcomes of Surgical management of central giant cell granuloma of the maxilla. Int J Oral Maxillofac Surg. 2006 Jan;35(1):60-6.
10. Pogrel MA. Calcitonin Therapy for Central Giant Cell Granuloma. J Oral Maxillofac Surg 61:649-653, 2003.
11. de Lange J, Rosenberg AJ, van den Akker HP, Koole R, Wirds JJ, van den Berg H. Treatment of central giant cell granuloma of the jaw with calcitonin. Int. J Oral Maxillofac. Surg. 1999; 28:372-376.
12. Kurtz M, Mesa M, Alberto P. Treatment of a central giant cell lesion of the mandible with intralesional glucocorticosteroids. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001; 91:636-7.
13. Carlos R, Sedano HO. Intralesional corticosteroids as an alternative treatment for central giant cell granuloma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 93:161-6.
14. Adornato M., Paticoff K.A. Intralesional corticosteroid injection for treatment of central giant-cell granuloma. J Am Dent Assoc. 2001 Feb; 132(2):186-90.
15. de Lange J, van den Akker HP, van den Berg H, Richel DJ, Gortzak RA. Limited regression of central giant cell granuloma by interferon alpha after failed calcitonin therapy: a report of 2 case. Int J Oral Maxillofac Surg. 2006 Sep;35(9):865-9.
16. Kaban LB, Troulis MJ, Ebb D, August M, Hornicek FJ, Dodson TB. Antiangiogenic Therapy with Interferon Alpha for Giant Cell Lesions of the Jaws. J Oral Maxillofac Surg. 2002 Oct;60(10):1103-11;
17. Kaban LB, Mulliken JB, Ezekowitz RA, Ebb D, Smith PS, Folkman J. Antiangiogenic Therapy of a Recurrent Giant Cell Tumor of the Mandible with Interferon Alfa-2a. Pediatrics. 1999 Jun;103(6 Pt 1):1145-9
18. Kaban LB, Troulis MJ, Ebb D, August M, Hornicek FJ, Dodson TB. Antiangiogenic therapy with interferon alpha for giant cell lesions of the jaws. J Oral Maxillofac Surg. 2002 Oct;60(10):1103-11
19. Goldman KE1, Marshall MK, Alessandrini E, Bernstein ML. Complications of alpha-interferon therapy for aggressive central giant cell lesion of the maxilla. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Sep;100(3):285-91.
2. De Lange J, Van den Akker HP. Clinical and radiological features of central giant-cell lesions of the jaw. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;99:464-70
3. Kruse-Lösler B, Diallo R, Gaertner C, Mischke KL, Joos U, Kleinheinz J. Central giant cell granuloma of the jaws: A clinical, radiologic, and histopathologic study of 26 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:346-54
4. Ciorba A, Altissimi G, Giansanti M. Giant cell granuloma of the maxilla: case report. Acta otorhinolaryngol Ital 24, 26-29, 2004
5. De Lange J, Van den Akker HP. Radiologic features of central giant cell granuloma of the jaw. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996;81:720-6
6. Sidhu MS, Parkash H, Sidhu SS. Central giant cell granuloma of jaws-review of 19 cases. Br J Oral Maxillofac Surg. 1995 Feb;33(1):43-6.
7. Stavropoulos F, Katz J.Central giant cell granulomas: A systematic review of the radiographic characteristics with the addition of 20 new cases. Dentomaxillofac Radiol. 2002 Jul;31(4):213-7.
8. Bataineh AB, Al-Khateeb T, Rawashdeh MA. The Surgical Treatment of Central Giant Cell Granuloma of the Mandible. J Oral Maxillofac Surg. 2002 Jul;60(7):756-61.
9. Rawashdeh MA, Bataineh AB, Al-Khateeb T. Long-term clinical and radiological outcomes of Surgical management of central giant cell granuloma of the maxilla. Int J Oral Maxillofac Surg. 2006 Jan;35(1):60-6.
10. Pogrel MA. Calcitonin Therapy for Central Giant Cell Granuloma. J Oral Maxillofac Surg 61:649-653, 2003.
11. de Lange J, Rosenberg AJ, van den Akker HP, Koole R, Wirds JJ, van den Berg H. Treatment of central giant cell granuloma of the jaw with calcitonin. Int. J Oral Maxillofac. Surg. 1999; 28:372-376.
12. Kurtz M, Mesa M, Alberto P. Treatment of a central giant cell lesion of the mandible with intralesional glucocorticosteroids. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001; 91:636-7.
13. Carlos R, Sedano HO. Intralesional corticosteroids as an alternative treatment for central giant cell granuloma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 93:161-6.
14. Adornato M., Paticoff K.A. Intralesional corticosteroid injection for treatment of central giant-cell granuloma. J Am Dent Assoc. 2001 Feb; 132(2):186-90.
15. de Lange J, van den Akker HP, van den Berg H, Richel DJ, Gortzak RA. Limited regression of central giant cell granuloma by interferon alpha after failed calcitonin therapy: a report of 2 case. Int J Oral Maxillofac Surg. 2006 Sep;35(9):865-9.
16. Kaban LB, Troulis MJ, Ebb D, August M, Hornicek FJ, Dodson TB. Antiangiogenic Therapy with Interferon Alpha for Giant Cell Lesions of the Jaws. J Oral Maxillofac Surg. 2002 Oct;60(10):1103-11;
17. Kaban LB, Mulliken JB, Ezekowitz RA, Ebb D, Smith PS, Folkman J. Antiangiogenic Therapy of a Recurrent Giant Cell Tumor of the Mandible with Interferon Alfa-2a. Pediatrics. 1999 Jun;103(6 Pt 1):1145-9
18. Kaban LB, Troulis MJ, Ebb D, August M, Hornicek FJ, Dodson TB. Antiangiogenic therapy with interferon alpha for giant cell lesions of the jaws. J Oral Maxillofac Surg. 2002 Oct;60(10):1103-11
19. Goldman KE1, Marshall MK, Alessandrini E, Bernstein ML. Complications of alpha-interferon therapy for aggressive central giant cell lesion of the maxilla. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Sep;100(3):285-91.
Published
2017-03-12
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Section
Review Articles
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