Cytological Diagnosis of Salivary Gland Lesions with Histopathological Correlation
Keywords:
FNAC, salivary gland, salivary gland tumors, diagnostic accuracy
Abstract
Background: The aim of this study was to demonstrate the diagnostic accuracy of FNAC in various salivary gland lesions and it’s correlation with histopathology, which helps in the appropriate management of the patient.Methods: A total of 86 patients were included in this study that was to be investigated for the salivary gland lesions. FNACs were performed using 22 gauge needle. Surgical specimens were received from 68 cases only they were processed and slides were prepared. The cytological and histopathological stained slides were correlated clinically.Result: Out of total 86 cases 54 were male and 32 were female patients with male to female ratio of 1.7:1. Most common age of presentation was between 21-40 years and maximum patients (42) were in this age group. In this study the most common site of involvement was parotid gland, out of total 86 cases 65 occurred in parotid gland. Mucoepidermoid carcinoma was diagnosed in 3 (3.48%) cases. 2 (2.32%) cases found to have acinic cell carcinoma and both the patients (100%) were male. 2 (2.32%) cases found to have Ca. Ex. Pleomorphic adenoma. Metastatic deposit was found in 1(1.16%) patient.Conclusion: FNAC of the salivary gland is a safe and reliable technique in the primary diagnosis of salivary gland lesions and has a high diagnostic accuracy, though in case of some tumors due to variable cytomorphology, histological examination is must and proves to be accurate for diagnosis. This study concluded that FNAC of the salivary gland tumors is accurate, simple, rapid and cost-effective for the patient. DOI: 10.21276/AABS.2017.1349References
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10. AtulaT. GrenmanR., and LaippalaP., “Fine-needle aspiration cytology of submandibular gland lesions,”The Journal of Laryngology & Otology, 1995; 109 (9):853–858. [7].
11. Layfield L. J. and Glasgow B. J., “Diagnosis of salivary gland tumors by fine-needle aspiration cytology: a review of clinical utility and pitfalls.” Diagnostic Cytopathology, 1991; 7(3): 267–272.
12. Jaiswal K N,Johari S P, Shrivastav A C, Shrikhande AV.” Study of Salivary Gland Neoplasms. Indian Medical Gazette-March 2015, 96-100.
2. Nagarkar N.M., Bansal S., Dass A. et al--Salivarygland tumors. Indian Journal of otolaryngology and head and neck surgery. 56(1): 31 – 34, 2004.
3. Epker B.N. and Henry F.A. — Clinical histopathologicand surgical aspects of Intraoral minor salivary glandtumors. Journal of oral surgery. 27: 792-804, 1969.
4. Jayaram G, Dashini M. Evaluation of fine needle aspiration cytology of salivary glands: an analysis of 141 cases. Malays J Pathol. 2001; 23: 93-100.
5. Stow N, Veivers D, Poole A. Fine–needle aspiration cytology in the management of salivary gland lesions: an Australian experience.Ear Nose Throat J. 2004; 83:128-31.
6. Rehman H, Khan MS, Wahid F, Ahmad I. A profile of parotid gland tumours from a tertiary care hospital in Peshawar.JPMI 2011; 25:158-62.
7. Lukas J, Duskova J. Fine needle aspiration biopsy in the diagnosis of tumors and non neoplastic lesions of salivary glands. Bratisl Lek Listy. 2006; 107: 12 - 5.
8. Piccioni LO, Fabiano B, Gemma M, Sarandria D, Bussi M. Fine needle aspiration cytology in diagnosis of parotid lesions. Acta Otorhinolarygol Ital. 2011; 31:1
9. Nguansangiam S. Jesdapatarakul S. Dhanarak N., and Sosrisakorn K., “Accuracy of fine needle aspiration cytology of salivary lesions: routine diagnostic experience in Bangkok,Thailand,”Asian Pacific Journal of Cancer Prevention,2012; 13(4):1583–1588.
10. AtulaT. GrenmanR., and LaippalaP., “Fine-needle aspiration cytology of submandibular gland lesions,”The Journal of Laryngology & Otology, 1995; 109 (9):853–858. [7].
11. Layfield L. J. and Glasgow B. J., “Diagnosis of salivary gland tumors by fine-needle aspiration cytology: a review of clinical utility and pitfalls.” Diagnostic Cytopathology, 1991; 7(3): 267–272.
12. Jaiswal K N,Johari S P, Shrivastav A C, Shrikhande AV.” Study of Salivary Gland Neoplasms. Indian Medical Gazette-March 2015, 96-100.
Published
2017-02-25
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