Clinicopathological profile of anaemia cases in adults (20-60 years) attending a rural hospital
Keywords:
Iron deficiency anemia, megaloblastic anemia, Nonmegaloblastic macrocytic anemia, Nutritional anemia.
Abstract
Background::Anemia is a worldwide problem with highest incidence in developing countries. India has the highest prevalence of nutritional anemia predominantly in women and children.Methods: An observational and analytical study was carried out for period of 12 months. We studied 261 adult patient for typing the anemia. We perform the hematology parameter by automated hematologyanalyzer, For confirmation PBS and bone marrow examination, serological test like serum iron profile , vit B12 and folic acid levels in blood is doneResult:Total 261 cases of anemia included in the study. Microcytic hypochromic anemia were63.2 %of cases, macrocytic anemia cases were 36.77% of cases. Large number of iron deficiency anemia’s were seen in female with reproductive age group and megaloblastic anemia seen with age 50-60 years of age in both sex.Conclusion: For the diagnosis of nutritional anemia haemogram by automated hematology parameter, PBS, serum iron profile , serum vit B12 and folic acid is required. DOI: 10.21276/AABS.1555References
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9. Matthew W. Short and Jason E. Domagalski. Iron Deficiency Anaemia. Evaluation and Management . Am Fam Physician 2013;87 (2):98-104.
10. Gangather T, Shrikanth P and Suneetha Y. Predictive value of iron store markers in anemia of chronic kidney disease. Journal of Chemical and Pharmaceutical Research. 2010;(3):400-410.
11. Berry S Skikne, Carol H Flowers and jams D cook. Serum Transferrin receptor:A Quantitative Measure of Tissue Iron Deficiency. Blood. 1990;7(9):1870-1876.
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13. Kamala Vanarsa, Yujin Ye,Jie Han ChunXie,Chandra Mohan and Tianfu Wu. Inflammation associated anemia and ferritin as disease marker in SLE. Arthritis Research and Therapy 2012;14:R182 doi:10.1186/ar4012
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15. Matthis Lorenz, Josef Kletzmayr, Agnes nPerschl, Alexander furrer, Walter H Horl and Gere Sunder- Plassmann. Anaemia and Iron Dficiencies amoung Long Term Renal Transplant Recipiant.Journal Of the American Society of Nephrology 2002 vol 13 (3) Page 794-797.
16. Salama Haq, Nasir Eqbal, Fatima Fayyaz and Tahira Tasneem. Serum B12 and folate levels in patient with megaloblastic change in bone marrow. Biomedica. 2012; vol 28:35-41.
17. Robert C Langan and Kimberly J Zawistoski. Update on vit B12 Deficiency. Am Fam Physician 2011; 83(12):1425-1430.
18. M Ramani, D Ranganath, O.H. RadhikaKrishna, K geetha, M Kiteeka, Puja Deshmukh. Clinicopathological Review of Megaloblastic Anemia in Children-A 7 year paediatric Hospital Experience. Journal of evolution of Medical and Dental Sciences. 2013; 2(19):4136-4142.
19. Jeevan Sekhar and Sally P. Stabler. Life threating megaloblastic pancytopenia with normal mean cell volume: case series.. Eur J Inteern Med 2007; 18 (7): 548-550
20. John Lindenbaum. Status of laboratory testing in the diagnosis of Megaloblastic anemia. Blood 1983;64 (4): 624-627.
21. M Premkumar, N Gupta, T Singh and T Velpandian. Cobalamin and Folic Acid Status in Relation to the Etiopathgenesis of Pancytopenia in Adult at a tertiary Care centre in North India. Anemia.2012; http//dx.doi.org/10.11/2012/707402
2. Erin McLean, Mary Cogswell, Ines Egli, Daniel Wojdyla and Bruno de Benoist. Worldwide prevalence of anaemia. Public Health Nutrition. 2009 Apr; 12(4):444-54.
3. Terri D. Johnson-Wimbley. Diagnosis and manegment of iron deficiency anemia in 21st century. Therap Adv Gastrointestinol.2011; May 4 (3): 177-184.
4. Neelam S Deshpande, Devkinandan Karva, Sharad Angerkhedker, Shishir Deshpande. Prevalence of anemia in adolesant girl and its co-relation with demographic factors. International Journal of Medicine and Public Health. 2013;3(4):235-239.
5. Uma Khanduri, Archna Sharma. Megaloblastic anaemia: Prevalence and causative factors. The National Medical Journal of India.2007;20 (4):172-175.
6. Robert T Means, Jr. Berti Glader. Anaemia Genaral Consideration. John Foester, George M Rodger and Frixos Paraskevas. Wintrobes Clinical Haematology. Volume I. Twelth Edition. Philedelphia; LIPPINCOTT WILLIUMS and WIKINS, a WOLKER KLUER bisiness. Page 779-807.
7. Fatin Al-Sayes, Mamdooh Gari, Safaa Qusti ,Nadiah Bagatian and Adel Abuzenadah. Prevalence of iron deficiency and iron deficiency anemia among females at university stage. Journal of Medical Laboratory and Diagnosis. 2011; vol 2(1):5-11.
8. Gerardo Alvarez- Uria, Praveen K. Naik, Manoranjan Midde, Pradeep S Yalla and Raghavkalyan Pakam . Prevalace and severity of anaemia Stratified by Age Gender in Rural India. Anemia; 2014. dx.doi.org/10.115/2014/176182.
9. Matthew W. Short and Jason E. Domagalski. Iron Deficiency Anaemia. Evaluation and Management . Am Fam Physician 2013;87 (2):98-104.
10. Gangather T, Shrikanth P and Suneetha Y. Predictive value of iron store markers in anemia of chronic kidney disease. Journal of Chemical and Pharmaceutical Research. 2010;(3):400-410.
11. Berry S Skikne, Carol H Flowers and jams D cook. Serum Transferrin receptor:A Quantitative Measure of Tissue Iron Deficiency. Blood. 1990;7(9):1870-1876.
12. Ralph O. Wallerstein, Jr, MD,San Francisco. Laboratory evaluation of anemia, West J Med 1987;146:443-451.
13. Kamala Vanarsa, Yujin Ye,Jie Han ChunXie,Chandra Mohan and Tianfu Wu. Inflammation associated anemia and ferritin as disease marker in SLE. Arthritis Research and Therapy 2012;14:R182 doi:10.1186/ar4012
14. Sheetal Patel, Seyed Monemian, Avesha Khalid and Harvey Dosik. Iron Deficiency anaemia in Adult Onset Still’s Disease With a Serum Ferritin of 26,387ug/L. Anemia .2011: 184748.Published online May 12, 2011.doi 10.115/2011/184748.
15. Matthis Lorenz, Josef Kletzmayr, Agnes nPerschl, Alexander furrer, Walter H Horl and Gere Sunder- Plassmann. Anaemia and Iron Dficiencies amoung Long Term Renal Transplant Recipiant.Journal Of the American Society of Nephrology 2002 vol 13 (3) Page 794-797.
16. Salama Haq, Nasir Eqbal, Fatima Fayyaz and Tahira Tasneem. Serum B12 and folate levels in patient with megaloblastic change in bone marrow. Biomedica. 2012; vol 28:35-41.
17. Robert C Langan and Kimberly J Zawistoski. Update on vit B12 Deficiency. Am Fam Physician 2011; 83(12):1425-1430.
18. M Ramani, D Ranganath, O.H. RadhikaKrishna, K geetha, M Kiteeka, Puja Deshmukh. Clinicopathological Review of Megaloblastic Anemia in Children-A 7 year paediatric Hospital Experience. Journal of evolution of Medical and Dental Sciences. 2013; 2(19):4136-4142.
19. Jeevan Sekhar and Sally P. Stabler. Life threating megaloblastic pancytopenia with normal mean cell volume: case series.. Eur J Inteern Med 2007; 18 (7): 548-550
20. John Lindenbaum. Status of laboratory testing in the diagnosis of Megaloblastic anemia. Blood 1983;64 (4): 624-627.
21. M Premkumar, N Gupta, T Singh and T Velpandian. Cobalamin and Folic Acid Status in Relation to the Etiopathgenesis of Pancytopenia in Adult at a tertiary Care centre in North India. Anemia.2012; http//dx.doi.org/10.11/2012/707402
Published
2017-07-11
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