A case of Synchronous Multifocus Gastric Adenocarcinoma.
Keywords:
synchronous multifocus gastric adenocarcinoma
Abstract
Synchronous neoplasms are defined as two or more primary tumors identified in the same patient, at the same time, in the same organ or in different organs. Here we present an interesting case of Synchronous Multifocus Gastric Adenocarcinoma with a concern that the diagnosis of synchronous multifocal gastric neoplasms can sometimes be missed during initial endoscopic investigations and during grossing sessions in histopathology units, making it obligatory for the surgeon and the histopathologist to be aware of such lesions.References
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Taro Isobe, Kousuke Hashimoto, Junya Kizaki, Naotaka Murakami, Keishiro Aoyagi, Kikuo Koufuji, Yoshito Akagi, andKazuo Shirouzu
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13) Nomura A, Grove JS, Stemmermann GN, Severson RK. A prospective study of stomach cancer and its relation to diet, cigarettes, and alcohol consumption. Cancer Res. 1990;50:627–631.
14) Ji BT, Chow WH, Yang G, McLaughlin JK, Gao RN, Zheng W, Shu XO, Jin F, Fraumeni JF, Gao YT. The influence of cigarette smoking, alcohol, and green tea consumption on the risk of carcinoma of the cardia and distal stomach in Shanghai, China. Cancer. 1996;77:2449–2457.
15) La Vecchia C, Negri E, Franceschi S, Gentile A. Family history and the risk of stomach and colorectal cancer. Cancer. 1992;70:50–55.
16) Morita M, Kuwano H, Baba H, Taketomi A, Kohnoe S, Tomoda H, Araki K, Saeki H, Kitamura K, Sugimachi K. Multifocal occurrence of gastric carcinoma in patients with a family history of gastric carcinoma. Cancer. 1998;83:1307–1311.
17) Otsuji E, Kuriu Y, Ichikawa D, Okamoto K, Hagiwara A, Yamagishi H. Clinicopathologic characteristics and prognosis of synchronous multifocal gastric carcinomas. Am J Surg. 2005;189:116–119.
18) Morita M, Kuwano H, Baba H, Taketomi A, Kohnoe S, Tomoda H, Araki K, Saeki H, Kitamura K, Sugimachi K. Multifocal occurrence of gastric carcinoma in patients with a family history of gastric carcinoma. Cancer. 1998;83:1307–1311.
19) Nasu J, Doi T, Endo H, Nishina T, Hirasaki S, Hyodo I. Characteristics of metachronous multiple early gastric cancers after endoscopic mucosal resection. Endoscopy. 2005;37:990–993.
20) Moertel CG, Bargen JA, Soule EH. Multiple gastric cancers; review of the literature and study of 42 cases. Gastroenterology. 1957;32:1095–1103.
2) A. Dąbrowski, A. Ciechański, G. WallnerAssociation of non-Hodgkin's lymphoma of stomach with other neoplasms of gastro-intestinal tract.GastroenterologiaPolska, 4 (4) (1997), pp. 427-429
3) “A Review of the Definition for Multiple Primary Cancers in the United States,” in Worshop Proceedings From December 4-6, 2002 in Princeton, New Jersey, H. L. Howe, Ed., North American Association of Central Cancer Registries, Springfield, Ill, USA, 2003.
4) Ribeiro U, Jorge UM, Safatle-Ribeiro AV, Yagi OK, Scapulatempo C, Perez RO, Corbett CE, Alves VA, Zilberstein B, Gama-Rodrigues J. Clinicopathologic and immunohistochemistry characterization of synchronous multiple primary gastric adenocarcinoma. J Gastrointest Surg. 2007;11:233–239.
5) Otsuji E, Kuriu Y, Ichikawa D, Okamoto K, Hagiwara A, Yamagishi H. Clinicopathologic characteristics and prognosis of synchronous multifocal gastric carcinomas. Am J Surg. 2005;189:116–119.
6) Morita M, Kuwano H, Baba H, Taketomi A, Kohnoe S, Tomoda H, Araki K, Saeki H, Kitamura K, Sugimachi K. Multifocal occurrence of gastric carcinoma in patients with a family history of gastric carcinoma. Cancer. 1998;83:1307–1311.
7) Borie F, Plaisant N, Millat B, Hay JM, Fagniez PL, De Saxce B. Treatment and prognosis of early multiple gastric cancer. Eur J Surg Oncol. 2003;29:511–514.
8) Nasu J, Doi T, Endo H, Nishina T, Hirasaki S, Hyodo I. Characteristics of metachronous multiple early gastric cancers after endoscopic mucosal resection. Endoscopy. 2005;37:990–993.
9) Characteristics and prognosis of synchronous multiple early gastric cancer
Taro Isobe, Kousuke Hashimoto, Junya Kizaki, Naotaka Murakami, Keishiro Aoyagi, Kikuo Koufuji, Yoshito Akagi, andKazuo Shirouzu
10) Nitta T, Egashira Y, Akutagawa H, Edagawa G, Kurisu Y, Nomura E, Tanigawa N, Shibayama Y. Study of clinicopathological factors associated with the occurrence of synchronous multiple gastric carcinomas. Gastric Cancer. 2009;12:23–30.
11) Chen JD, Kearns S, Porter T, Richards FM, Maher ER, Teh BT. MET mutation and familial gastric cancer. J Med Genet. 2001;38:E26. [PMC free article]
12) Kato I, Tominaga S, Matsumoto K. A prospective study of stomach cancer among a rural Japanese population: a 6-year survey. Jpn J Cancer Res. 1992;83:568–575.
13) Nomura A, Grove JS, Stemmermann GN, Severson RK. A prospective study of stomach cancer and its relation to diet, cigarettes, and alcohol consumption. Cancer Res. 1990;50:627–631.
14) Ji BT, Chow WH, Yang G, McLaughlin JK, Gao RN, Zheng W, Shu XO, Jin F, Fraumeni JF, Gao YT. The influence of cigarette smoking, alcohol, and green tea consumption on the risk of carcinoma of the cardia and distal stomach in Shanghai, China. Cancer. 1996;77:2449–2457.
15) La Vecchia C, Negri E, Franceschi S, Gentile A. Family history and the risk of stomach and colorectal cancer. Cancer. 1992;70:50–55.
16) Morita M, Kuwano H, Baba H, Taketomi A, Kohnoe S, Tomoda H, Araki K, Saeki H, Kitamura K, Sugimachi K. Multifocal occurrence of gastric carcinoma in patients with a family history of gastric carcinoma. Cancer. 1998;83:1307–1311.
17) Otsuji E, Kuriu Y, Ichikawa D, Okamoto K, Hagiwara A, Yamagishi H. Clinicopathologic characteristics and prognosis of synchronous multifocal gastric carcinomas. Am J Surg. 2005;189:116–119.
18) Morita M, Kuwano H, Baba H, Taketomi A, Kohnoe S, Tomoda H, Araki K, Saeki H, Kitamura K, Sugimachi K. Multifocal occurrence of gastric carcinoma in patients with a family history of gastric carcinoma. Cancer. 1998;83:1307–1311.
19) Nasu J, Doi T, Endo H, Nishina T, Hirasaki S, Hyodo I. Characteristics of metachronous multiple early gastric cancers after endoscopic mucosal resection. Endoscopy. 2005;37:990–993.
20) Moertel CG, Bargen JA, Soule EH. Multiple gastric cancers; review of the literature and study of 42 cases. Gastroenterology. 1957;32:1095–1103.
Published
2017-09-05
Issue
Section
Case Reports
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