Hematological profile of pregnant and non-pregnant females: A comparative study in a tertiary care hospital in Haryana, India

  • Shveta Lukhmana
  • Deepsikha Rana
  • Mukta Pujani
  • Nimisha Sharma
  • Rashmi Ahuja


Background: There are marked variations in the various  haematological parameters during the pregnancy and also during the  different trimesters of pregnancy. Due to paucity of literature on the haematological profile of pregnant population in Haryana, India the present study aims to fill the gap by drawing a comparison between cases and controls for the different haematological indices among patients attending a tertiary care hospital and also highlight the difference among the pregnant women across the three trimester(s).Methods: A case control study was conducted to study and compare the haematological profile among 119 pregnant and 119 non-pregnant women attending the out-patient department of ESIC medical, college & hospital Faridabad,a tertiary care hospital in Faridabad district of Haryana. Statistical analysis of the data was done using SPSS software 17.0. Unpaired students t-test was applied to compare various haematological parameters between cases and controls. One way Anova was applied and Tukey and Games Howell post hoc test was applied to study between group and within group differences among the three trimester with hematological indices. Result: White blood cells (WBCs), neutrophils, nucleated Red Blood Cells(NRBC), immature granulocytes(IG) and Red cell Distribution Width-Standard deviation (RDW-SD) were found to be higher among cases as compared to controls. Hemoglobin, hematocrit, mean corpuscular volume(MCV),mean corpuscular haemoglobin(MCH), lymphocyte and platelet count were found to be significantly higher among controls as compared to cases. On one-way ANOVA a statistically significant difference in hemoglobin, hematocrit, WBCs, neutrophils, lymphocytes, immature granulocytes and nucleated RBC’s was found between the three trimester(s).Conclusion:  Haemoglobin and haematocrit and platelets showed a fall while WBCs and neutrophils showed a rise when compared to the nonpregnant state.The findings of the study will be a value addition in comparative analysis  of studies between pregnant and non-pregnant females.  DOI: 10.21276/AABS.1701

Author Biography

Department of Pathology, Associate Professor.


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Original Article