Prevalence of Dyslipidemia in Adults: An Epidemiological Study in Kavaratti Island, Lakshadweep
Keywords:
Dyslipidemia, Epidemiology, Adults, Kavaratti, Lakshadweep
Abstract
Background: Dyslipidemia is an important, modifiable chronic heart disease (CHD) risk factor. Previous studies in various parts of the world including India have reported the prevalence of dyslipidemia particularly in urban population. However, its prevalence in Lakshadweep islands has not been well documented.Methods: A cross-sectional study for the prevalence of dyslipidemia among adult population in Lakshdweep ( Kavaratti Island ) using the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP III) guidelines was conducted.Result: 300 subjects recruited (160 men; 140 women) averaged 51.91 and 49.41 years of age, respectively (range: 39-85). After 12 hours fasting, serum samples were collected. Total cholesterol, triglycerides, low-density lipoprotein (LDL-C) and high-density lipoprotein (HDL-C) cholesterols were measured. The prevalence of hypercholesterolemia (> 200 mg/dL), hypertriglyceridemia (>150 mg/dL), high LDL-C (> 130 mg/dL) and low HDL-C (< 40 mg/dL) was 96.428, 52.857, 15.714, 78.571, 94.285 % respectively in women . Women had a slightly higher prevalence of hypercholesterolemia 52.857% and high LDL-C 78.571 % than men, 46.25 and 62.5% respectively while the prevalence of hypertriglyceridemia was approximately 2-3 fold less in females (female 15.71% and males 38.125%). The prevalence of dyslipidemia was present in all age groups in almost similar proportion .One striking feature that is of low HDL was observed in 90 to 100 % in different tertile of age.Conclusion: The present study demonstrated a high prevalence of dyslipidemia in Lakshadweep (Kavaratti Island) adults with specifically low HDL; hence, primary lipid screening should be considered for all age groups in this area.References
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2. Choi SJ, Park SH, Lee KS, Park HY. The prevalence, awareness and treatment of high low density lipoprotein cholesterol in Korean adults without coronary heart disease - the third Korea national health and nutrition examination survey, 2005. Korean Circulation Journal 2012; 42: 86–94.
3. Roth GA, Fihn SD, Mokdad AH, et al. High total serum cholesterol, medication coverage and therapeutic control: an analysis of national health examination survey data from eight countries. Bull World Health Organ 2011;89: 92–101.
4. Chapman MJ, Ginsberg HN, Amarenco P, et al. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. European Heart Journal 2011;32: 1345–61.
5. National Cholesterol Education Program (NCEP) Expert Panel on Detection and Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III), “Third report of the national cholesterol education program (NCEP) expertpanel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation 2002;106:3143–421.
6. Gama R, Elfatih AB, Anderson NR. Ethnic differences in total and HDL cholesterol concentrations: Caucasians compared with predominantly Punjabi Sikh Indo-Asians. Ann Clin Biochem 2002;39: 609-11.
7. Misra A, Luthra K, Vikram NK. Dyslipidemia in Asian Indians: Determinants and Significance. J Assoc Physicians India 2004; 52: 137-42.
8. Chadha SL, Gopinath N, Shekhawat S. Urban-rural differences in the prevalence of coronary heart disease and its risk factors in Delhi. Bull World Health Organ 1997;75:31-8.
9. Gopinath N, Chadha SL, Jain P, Shekhawat S, Tandon R. An epidemiological study of obesity in adults in the urban population of Delhi. J Assoc Physicians India 1994;42:212-5.
10. Misra A, Pandey RM, Devi JR, et al. High prevalence of diabetes, obesity and dyslipidaemia in urban slum population in northern India. Int J Obes Relat Metab Disord 2001;25:1722-9.
11. Misra A, Sharma R, Pandey RM, Khanna N. Adverse profile of dietary nutrients, anthropometry and lipids in urban slum dwellers of northern India. Eur J Clin Nutr 2001;55:727-34.
12. Yamwong P, Assantachai P, Amornrat A. Prevalence of dyslipidemia in the elderly in rural areas of Thailand. Southeast Asian J Trop Med Public Health 2000; 31: 158-62.
Published
2015-09-29
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