Primary Ewing sarcoma of scalp diagnosed on cytology: A rare case report

  • Ankit Kaushik VMMC and Safdarjung Hospital, GGSIPU
  • Sakshi Sirswal
  • Kusum Gupta
  • Sachin Kolte
  • Disha Arora
Keywords: Ewing sarcoma, Cytology, Scalp


Primary Ewing sarcoma is small round cell tumour of neuroectodermal origin. We report a case of 16 year old female presenting with large cystic, osteolytic mass lesion in temporal region. The cytology showed loose and cohesive cluster of small round epithelial cells that were CD 99 and synaptophysin positive on immunocytochemistry.Primary scalp Ewing sarcoma is very rare, and can present with cystic lesion. FNAC along with immunocytochemistry provides early opportunity for diagnosis and treatment.   


1. Buch AC, Panicker N, Sarawagi S, Anwekar S, Kharat AT. Fine needle aspiration cytology diagno-sis of paravertebral extraosseus Ewing’s sarcoma. Journal of Cytology. 2010;27:146-8.

2. Lallu S, Naran S, Kenwright D, Bethwaite P. Fine needle aspiration cytology of unsuspected metas-tatic primitive neuroectodermal tumour (PNET): a case report. N Z J Med Lab Sci 2012; 66: 74-7.

3. Krishnamani K, Kumar TN, Gandhi LV, Raghunadharao D, Sadashivudu G, Megha U. Pri-mary ewing's sarcoma of the cranium: case series and review of literature. J Cancer Res Ther.2014;10: 377-80.

4. Vohra VG. Roentgen manifestations in Ewing′s sarcoma. A study of 156 cases. Cancer 1967;20:727-33.

5. Pritchard DJ, Dahlin DC, Dauphine RT, Taylor WF, Beabout JW. Ewing′s sarcoma. A clinicopathologi-cal and statistical analysis of patients surviving five years or longer. J Bone Joint Surg Am 1975;57:10-6.

6. Coley BL.: Neoplasms of Bone and related Condi-tions. New York: Paul B Hoeber 1949. p. 297-318.

7. Alvarez-Berdecia A, Schut L, Bruce DA. Localized primary intracranial Ewing′s sarcoma of the orbital roof. Case report. J Neurosurg 1979;50:811-3.

8. Bordia S, Meena S, Meena BK, Rajak V, Nagappa DK, Krishnamurthy J. FNAC of Extra-Skeletal Ewing’s Sarcoma of the Parotid Gland. Iranian Journal of Pathology .2011;6 (4): 208 – 11.

9. Kaptan K, Bhagat V, Dudhat R, Italiya S, Shah M. Unusual occurrence of Ewings sarcoma/PNET with pregnancy: 2 cases and literature review. Annals Of Pathology And Laboratory Medicine, 2014:1(2), C5-C9.

10. Guiter GE, Gamboni MM, Zakowski MF. The Cy-tology of Extraskeletal Ewing Sarcoma. Cancer (Cancer Cytopathol) 1999;87:141–8.
Case Reports