Intracranial chondromas : A retrospective cross sectional analysis of this rare tumor in tertiary hospital, Coimbatore
Keywords:
Chondromas, Calcification, Chondrocytes, Spheno-ethmoid
Abstract
Background: Chondromas are benign tumors that may be found in any part of the body. Tumors of cartilaginous origin presenting as an intracranial neoplasm, are very rare,[0.2-0.3%]. There are many hypotheses regarding its origin in the intracranial location. Diagnosing this tumor is mandatory as treatment and follow up depends upon the exact diagnosis. A retrospective cross sectional studyAim: To diagnose intracranial chondroma and to calculate the incidence, mean age, sex predilection and site predilection of this rare tumor in our hospital set up.Method: All central nervous tumor cases that were diagnosed during May 2011- May 2014 in our hospital was evaluated. From that, cases diagnosed as Intracranial chondromas was reevaluated. The incidence of this tumor among the central nervous system tumors was calculated. From this, the rarity of this tumor in our setup is established. Along with that the differential diagnosis and treatment options were also studied.Results: Of all the two hundred eighty Central nervous system tumors reported during our study period, only two cases of intracranial chondroma was reported in our hospital. The incidence of Central nervous tumor in our hospital was 2.4% per year. The calculated incidence of Intra cranial Chondroma was 0.2% during our study period. This correlated with the study of Chorobski et al. The mean age was calculated as 41 years. There was an equal gender distribution and site from which the tumor arose was also analyzed.Conclusion: In this cross sectional study, the diagnostic approach and the methods to rule out each differentials are analyzed. The incidence of intracranial chondromas among the central nervous system tumor was calculated and the rarity established.Equal gender distribution, mean age of occurrence of this tumor and the site predilection correlated with other studies.References
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14. Mohammad Sarwar, Leonard E. Swischuk,2 And Mannie M. Schechte. Intracranial chondromas. Am J Roentgenol 1976;127:973-977.
15. Delgado-López P, Martín-Velasco V, Galacho-Harriero A, Castilla-Díez J, Rodríguez-Salazar A, Echevarría-Iturbe C. Large chondroma of the dural convexity in a patient with Noonan's syndrome: Case report and review of the literature. Neurocirugía. 2007;18(3).
16. Palacios E. Intracranial Solitary Chondroma Of Dural Origin. American Journal of Roentgenology. 1970;110(1):67-70.
17. Çolpan E, Attar A, Erekul S, Arasıl E. Convexity dural chondroma: a case report and review of the literature. Journal of Clinical Neuroscience. 2003;10(1):106-108.
18. Fountas K, Stamatiou S, Barbanis S, Kourtopoulos H. Intracranial falx chondroma: Literature review and a case report. Clinical Neurology and Neurosurgery. 2008;110(1):8-13.
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20. Aoki T, Tashiro Y, Fujita K, Kajiwara M. A case report of the chondroma arising from the falx cerebri. No shinkei geka Neurological surgery [Internet]. 2005 [cited 26 September 2015];33(10):979-984.
21. Khosrovi H, Sadrolhefazi A, el-Kadi H, Bloomfield S, Schochet S. Intradural convexity chondroma: a case report and review of diagnostic features. The west virginia Medical journal. 2000;96(6):612-616.
22. Patel A, Munthali L, Bodi I. Giant cystic intracranial chondroma of the falx with review of literature. Neuropathology. 2009;29(3):315-317.
23. Kozłowska K, Bień D, Niemczyk K. Chondroma of the skull base. Otolaryngologia polska The Polish otolaryngology [Internet]. 2003 [cited 26 September 2015];58(5):995-998.
24. Nakazawa T, Inoue T, Suzuki F, Nakasu S, Handa J. Solitary intracranial chondroma of the convexity dura: case report. Surgical Neurology. 1993;40(6):495-498.
25. Kurt E, Beute G, Sluzewski M, van Rooij W, Teepen J. Giant chondroma of the falx. Journal of Neurosurgery. 1996;85(6):1161-1164.
2. Li T, Chen Y, Lin S, Tseng S. Chondroma of the Falx — Case Report. Tzu Chi Med J 2005. 2015;17(4):269-272.
3. Abbasi A, Ardalan F, Miri S, Shahriarian S, Tajik F. Chondroma of Falx: Case Report of a Rare Condition. Acta Medica Iranica. 2012;50(3):222-224.
4. Brownlee R, Sevick R, Rewcastle N, Tranmer d. Radiologic-Pathologic Correlation Intracranial Chondroma. AJNR. 1997;18:889-893.
5. Coene B, Gilliard C, Grandin C, Nisolle J, Trigaux J, Lahdou J. Unusual Location of an Intracranial Chondroma. AJNR. 1997;18:573-575.
6. Uddin et al.: Intracranial cystic chondroma: a case report. Journal of Medical Case Reports 2012 6:432.
7. Maheshwari V, Mehdi G, Varshney M, Jain A, Vashishtha S, Gaur K, Srivastava VK. Intracranial chondroma: a rare entity. BMJ Case Reports 2011; 10.1136/bcr.03.2011.4047
8. Wu W, Lapi A. Primary non-skeletal intracranial cartilaginous neoplasms: report of a chondroma and a mesenchymal chondrosarcoma. Journal of Neurology, Neurosurgery & Psychiatry. 1970;33(4):469-475.
9. Park J, Jeun S. An Intracranial Chondroma with Intratumoral Hemorrhage: A Case Report and Review of the Literature. Brain Tumor Research and Treatment. 2013;1(1):42.
10. Boyar B, Killr C, Akalan N, Giirsoy F, Sekerci Z, Sav A. INTRADURAL SOLITARY CHONDROMA A Case Report. Turkish Neurosurgery. 1990;1:143-145.
11. Pauranik A, Mahore A, Kataria NG. Giant chondroma of the falx. Neurol India [serial online] 2012 [cited 2015 Sep 20];60:364-6.
12. Sharafeddine H, Elias E, Jabbour M, Najjar MW. Giant Convexity Chondroma of the Dura Matter Presenting with Epilepsy. Austin J Neurol Disord Epilepsy. 2014;1(1): 3
13. Oz Atalay F, Ozgun G, Tolunay S, Bekar A. Intracranial Extra-axial Chondroma: A Case Report. Journal of Nippon Medical School. 2014;81(1):35-39.
14. Mohammad Sarwar, Leonard E. Swischuk,2 And Mannie M. Schechte. Intracranial chondromas. Am J Roentgenol 1976;127:973-977.
15. Delgado-López P, Martín-Velasco V, Galacho-Harriero A, Castilla-Díez J, Rodríguez-Salazar A, Echevarría-Iturbe C. Large chondroma of the dural convexity in a patient with Noonan's syndrome: Case report and review of the literature. Neurocirugía. 2007;18(3).
16. Palacios E. Intracranial Solitary Chondroma Of Dural Origin. American Journal of Roentgenology. 1970;110(1):67-70.
17. Çolpan E, Attar A, Erekul S, Arasıl E. Convexity dural chondroma: a case report and review of the literature. Journal of Clinical Neuroscience. 2003;10(1):106-108.
18. Fountas K, Stamatiou S, Barbanis S, Kourtopoulos H. Intracranial falx chondroma: Literature review and a case report. Clinical Neurology and Neurosurgery. 2008;110(1):8-13.
19. Sebbag M, Schmidt V, Leboucq N, Bitoun J, Castan P, Frerebeau P. Dura mater chondroma. A case report and review of the literature.Journal de radiologie [Internet]. 1989 [cited 26 September 2015];71(8-9):495-498.
20. Aoki T, Tashiro Y, Fujita K, Kajiwara M. A case report of the chondroma arising from the falx cerebri. No shinkei geka Neurological surgery [Internet]. 2005 [cited 26 September 2015];33(10):979-984.
21. Khosrovi H, Sadrolhefazi A, el-Kadi H, Bloomfield S, Schochet S. Intradural convexity chondroma: a case report and review of diagnostic features. The west virginia Medical journal. 2000;96(6):612-616.
22. Patel A, Munthali L, Bodi I. Giant cystic intracranial chondroma of the falx with review of literature. Neuropathology. 2009;29(3):315-317.
23. Kozłowska K, Bień D, Niemczyk K. Chondroma of the skull base. Otolaryngologia polska The Polish otolaryngology [Internet]. 2003 [cited 26 September 2015];58(5):995-998.
24. Nakazawa T, Inoue T, Suzuki F, Nakasu S, Handa J. Solitary intracranial chondroma of the convexity dura: case report. Surgical Neurology. 1993;40(6):495-498.
25. Kurt E, Beute G, Sluzewski M, van Rooij W, Teepen J. Giant chondroma of the falx. Journal of Neurosurgery. 1996;85(6):1161-1164.
Published
2015-10-25
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