Urine Cytology: A Review
Keywords:
Urine, Cytology,
Abstract
Urine cytology is being studied since many years. This simple and cost effective test can help in diagnosis of urothelial malignancies. It has undergone a series of modifications in accordance with changes in histopathological classifications. Various systems for reporting urine cytology were being followed. But still there were difficulties and confusion in patient management. As such there were no clear cut criteria which led to lack of interobserver reproducibility. With the upcoming of The Paris System of reporting urine cytology, many of the doubts cleared. This system mentions addresses the problem of sample adequacy and clearly mentions the criteria for the various categories. To top it up, it also gives clear cut guidelines for the management of each of the categories. This review gives a glimpse of the various reporting systems with special emphasis on The Paris System of urine cytology.References
1. Rathert P. History of Urinary Cytology. Berlin Heidelberg. Springer 1993.
2. Sanders WR. Cancer of the bladder. Fragments forming urethral plugs discharged in the urine: Concentric colloid bodies. Edinb J Med 1864;10:273‑4
3. Papanicolaou GN, Marshall VF. Urine sediment smears as a diagnostic procedure in cancers of the urinary tract. Science 1945;101:519‑20.
4. Ploeg M, Aben KK, Kiemeney LA. The present and future burden of urinary bladder cancer in the world. World J Urol 2009; 27:289.
5. www.cancer.org
6. Sullivan PS, Chan JB, Levin MR, Rao J. Urine cytology and adjunct markers for detection and surveillance of bladder cancer. American Journal of Translational Research. 2010;2(4):412-440.
7. Jesse S. Voss, Benjamin R. Kipp, Angela K. Krueger, Amy C. Clayton, Kevin C.Halling, R. Jeffrey Karnes, Michael R. Henry, Thomas J. Sebo. Changes in Specimen Preparation Method May Impact Urine Cytologic Evaluation. American Journal of Clinical Pathology Sep 2008, 130 (3) 428-433
8. Papanicolaou GN. Cytology of the urine sediment in neoplasms of the urinary tract. J Urol. 1947;57:375-379.
9. Koss LG, Bartels PH, Sychra JJ, Wied GL. Diagnostic cytologic sample profiles in patients with bladder cancer using TICAS system. Acta Cytol. 1978;22:392-397.
10. Koss LG. Diagnostic Cytopathology and Its Histopathologic Basis. 5th ed. Vol 2. Philadelphia, PA: JB Lippincott Company; 2006.
11. Murphy WM, Soloway MS, Jukkola AF, Crabtree WN, Ford KS. Urinary cytology and bladder cancer. The cellular features of transitional cell neoplasms. Cancer. 1984;53:1555-1565.]
12. Ooms EC, Veldhuizen RW. Cytological criteria and diagnostic terminology in urinary cytology. Cytopathology. 1993;4:51-54.
13. Layfield LJ, Elsheikh TM, Fili A, Nayar R, Shidam V; Papanicolaou Society of Cytopathology. Review of the state of the art and recommendations of the Papanicolaou Society of Cytopathology for urinary cytology procedures and reporting: the Papanicolaou Society of Cytopathology Practice Guidelines Task Force. Diagn Cytopathol. 2004;30:24-30.
14. Owens, C. L., VandenBussche, C. J., Burroughs, F. H. and Rosenthal, D. L. (2013), A review of reporting systems and terminology for urine cytology . Cancer Cytopathology, 121: 9–14. doi: 10.1002/cncy.21253
15. Rosenthal DL, Wojcik EM, Kurtycz DFI. The Paris System for reporting Urine Cytology. New York. Springer; 2016.
2. Sanders WR. Cancer of the bladder. Fragments forming urethral plugs discharged in the urine: Concentric colloid bodies. Edinb J Med 1864;10:273‑4
3. Papanicolaou GN, Marshall VF. Urine sediment smears as a diagnostic procedure in cancers of the urinary tract. Science 1945;101:519‑20.
4. Ploeg M, Aben KK, Kiemeney LA. The present and future burden of urinary bladder cancer in the world. World J Urol 2009; 27:289.
5. www.cancer.org
6. Sullivan PS, Chan JB, Levin MR, Rao J. Urine cytology and adjunct markers for detection and surveillance of bladder cancer. American Journal of Translational Research. 2010;2(4):412-440.
7. Jesse S. Voss, Benjamin R. Kipp, Angela K. Krueger, Amy C. Clayton, Kevin C.Halling, R. Jeffrey Karnes, Michael R. Henry, Thomas J. Sebo. Changes in Specimen Preparation Method May Impact Urine Cytologic Evaluation. American Journal of Clinical Pathology Sep 2008, 130 (3) 428-433
8. Papanicolaou GN. Cytology of the urine sediment in neoplasms of the urinary tract. J Urol. 1947;57:375-379.
9. Koss LG, Bartels PH, Sychra JJ, Wied GL. Diagnostic cytologic sample profiles in patients with bladder cancer using TICAS system. Acta Cytol. 1978;22:392-397.
10. Koss LG. Diagnostic Cytopathology and Its Histopathologic Basis. 5th ed. Vol 2. Philadelphia, PA: JB Lippincott Company; 2006.
11. Murphy WM, Soloway MS, Jukkola AF, Crabtree WN, Ford KS. Urinary cytology and bladder cancer. The cellular features of transitional cell neoplasms. Cancer. 1984;53:1555-1565.]
12. Ooms EC, Veldhuizen RW. Cytological criteria and diagnostic terminology in urinary cytology. Cytopathology. 1993;4:51-54.
13. Layfield LJ, Elsheikh TM, Fili A, Nayar R, Shidam V; Papanicolaou Society of Cytopathology. Review of the state of the art and recommendations of the Papanicolaou Society of Cytopathology for urinary cytology procedures and reporting: the Papanicolaou Society of Cytopathology Practice Guidelines Task Force. Diagn Cytopathol. 2004;30:24-30.
14. Owens, C. L., VandenBussche, C. J., Burroughs, F. H. and Rosenthal, D. L. (2013), A review of reporting systems and terminology for urine cytology . Cancer Cytopathology, 121: 9–14. doi: 10.1002/cncy.21253
15. Rosenthal DL, Wojcik EM, Kurtycz DFI. The Paris System for reporting Urine Cytology. New York. Springer; 2016.
Published
2016-03-09
Issue
Section
Review Articles
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
