An Indian Study of Computerized Pulmonary Function Tests in Patients Referred to Physiology Department
AbstractBackground: Obesity is a modern day epidemic. Pulmonary function tests are likely to be compromised to varying degrees in these individuals, thus affecting their artificial ventilation under general anesthesia. It is thus important to study the pattern of pulmonary function in these subjects in a group likely to undergo surgery for varying reasons. Materials and Methods: 30 male subjects between 45-60 years attending the surgical outpatient with a body mass index [BMI] of more than 25kg/m² who qualified as obese and a similar number of subjects with BMI < 25kg/m² as controls were randomly selected. Flow Volume loop, FEV1, FVC and FEV1/ FVC were recorded using computerized spirometer. Results: FEV1, FVC and FEV1/FVC ratio measured in obese patients were significantly reduced (p < 0.05) when compared to normal BMI individuals. Conclusion: The incidence of restrictive tendency is more in the obese as compared to controls. As the changes in respiratory mechanics due to obesity are almost completely reversible, early intervention in such patients will ensure lesser chance of complications on the operation table and post-operatively. With the advent of computerized spirometry analysis of flow-volume loops is indeed of great help to the obese.
Health Implications of Obesity. NIH Consensus Statement Online 1985 Feb 11-13 [cited 2012 Nov 27]; 5(9):1-7
World health statistics – A snapshot of global health. Published by World Health Organisation. Available online at http://www.who.int/gho/publications / world_health_statistics /EN_WHS2012_Brochure.pdf
Agrawal PK. Emerging Obesity in Northern Indian States: A Serious threat for Health. Paper presented at IUSSP Conference, Bangkok, held on June 10-12, 2002. Accessed on November 28,2012 from http://188.8.131.52/Bangkok2002/S7Agrawal.pdf
J.P.Adams and P.G.Murphy. Obesity in anaesthesia and intensive care. Br J Anaesth 2000; 85(1): 91-108
DS DeLorey, BL Wyrick and TG Babb. Mild-to-moderate obesity: implications for respiratory mechanics at rest and during exercise in young men. International Journal of Obesity (2005) 29, 1039–1047
Jones RL, Nzekwu MM. The effects of body mass index on lung volumes. Chest 2006;130: 827–833.
Ochs-Balcom HM, Grant BJB, Paola Muti, Sempos CT et al. Pulmonary Function and Abdominal Adiposity in the General Population. Chest 2006; 129(4): 853-862
R. A. Watson, N. B. Pride, E. Louise Thomas et al. Reduction of Total Lung Capacity in
Obese Men: Comparison of Total Intrathoracic And Gas Volumes. J Appl Physiol 2010;
Christopher Zammit, Helen Liddicoat, Ian Moonsie, Himender Makker. Obesity and
respiratory diseases. International Journal of General Medicine 2010:3: 335–343
Misra A, Chowbey P, Makkar BM, Vikram NK, Wasir JS, Chadha D, et al. Consensus
statement for diagnosis of obesity, abdominal obesity and the metabolic syndrome for
Asian Indians and recommendations for physical activity, medical and surgical
management. J Assoc Physicians India 2009; 57: 163-70.
Durga Prasada Rao and Venkateswara A Rao: Morbidly obese parturient: Challenges for
the anaesthesiologist, including managing the difficult airway in obstetrics. What is new:
Indian J Anaesth. 2010 Nov-Dec; 54(6): 508–521.
Stephen O'Rahilly and I.Sadaf Farooqi. Genetics of obesity. Phil. Trans. R. Soc. B 2006;
Babb, Ranasinghe, Comeau, et al. Dyspnea on Exertion in Obese Women. Am J Respir
Crit Care Med 2008; 178: 116–123
Wannamethee SG, Shaper AG, Whincup PH. Body fat distribution, body composition,
and respiratory function in elderly men. Am J Clin Nutr 2005;82:996 –1003
Leduc D, Cappello M, Gevenois PA, De Troyer A. Mechanics of the canine diaphragm in
ascites: a CT study. J Appl Physiol 2008;104: 423–428
Leduc D and De Troyer A. Dysfunction of the canine respiratory muscle pump in ascites.
J Appl Physiol 2007;102: 650-657
McCarthy K, Dweik R A et al. Pulmonary function testing. Available online at
Mahajan S, Arora AK, Gupta P. Obesity and Spirometric Ventilatory Status Correlation
in Adult Male Population of Amritsar. National Journal of Physiology, Pharmacy and
Pharmacology 2012; 2(2): 93-98
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).