Sperm Selection in Assisted Reproduction Techniques
Short Review
Keywords:
Sperm selection, assisted reproduction techniques, DNA damage, DNA fragmentation, apoptosis, in vitro fertilization
Abstract
Quality of sperm is a critical factor to success in terms of pregnancy rates in assisted reproduction treatments (ART). There is an increasing interest in improving procedures of sperm selection before in vitro fertilization with or without intracytoplasmic sperm injection. And since DNA abnormalities are known to have negative correlation with ART outcomes, novel approaches in sperm laboratory techniques are involved in select cells with normal DNA.References
1. Malizia BA, Hacker MR, Penzias AS. 2009. Cumulative live-birth rates after in vitro fertilization. N Engl J Med 360(3):236-43.
2. World Health Organization, Department of Reproductive Health and Research. 2010. WHO laboratory manual for the examination and processing of human semen.. (Fifth edition).
3. García-Herrero S, Garrido N, Martinez-Conejero JA, Remohi J, Pellicer A, Meseguer M. 2011. Differential transcriptomic profile in spermatozoa achieving pregnancy or not via ICSI. Reprod Biomed Online 22(1):25-36.
4. Ainsworth C, Nixon B, Aitken RJ. 2005. Development of a novel electrophoretic system for the isolation of human spermatozoa. Hum Reprod 20(8):2261-70.
5. Seli E, Gardner DK, Schoolcraft WB, Moffatt O, Sakkas D. 2004. Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization. Fertil Steril 82(2):378-83.
6. Tavalaee M, Razavi S, Nasr-Esfahani MH. 2009. Influence of sperm chromatin anomalies on assisted reproductive technology outcome. Fertil Steril 91(4):1119-26
7. Boitrelle F, Guthauser B, Alter L, Bailly M, Bergere M, Wainer R, Vialard F, Albert M, Selva J. 2014. High-magnification selection of spermatozoa prior to oocyte injection: Confirmed and potential indications. Reprod Biomed Online 28(1):6-13.
8. Tarozzi N, Nadalini M, Bizzaro D, Serrao L, Fava L, Scaravelli G, Borini A. 2009. Sperm-hyaluronan-binding assay: Clinical value in conventional IVF under italian law. Reprod Biomed Online 19 Suppl 3:35-43.
9. Evenson DP, Larson KL, Jost LK. 2002. Sperm chromatin structure assay: Its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques. J Androl 23(1):25-43.
10. Tarozzi N, Bizzaro D, Flamigni C, Borini A. 2007. Clinical relevance of sperm DNA damage in assisted reproduction. Reprod Biomed Online 14(6):746-57.
11. Cayli S, Sakkas D, Vigue L, Demir R, Huszar G. 2004. Cellular maturity and apoptosis in human sperm: Creatine kinase, caspase-3 and bcl-XL levels in mature and diminished maturity sperm. Mol Hum Reprod 10(5):365-72.
12. Said TM, Agarwal A, Zborowski M, Grunewald S, Glander HJ, Paasch U. 2008. Utility of magnetic cell separation as a molecular sperm preparation technique. J Androl 29(2):134-42.
2. World Health Organization, Department of Reproductive Health and Research. 2010. WHO laboratory manual for the examination and processing of human semen.. (Fifth edition).
3. García-Herrero S, Garrido N, Martinez-Conejero JA, Remohi J, Pellicer A, Meseguer M. 2011. Differential transcriptomic profile in spermatozoa achieving pregnancy or not via ICSI. Reprod Biomed Online 22(1):25-36.
4. Ainsworth C, Nixon B, Aitken RJ. 2005. Development of a novel electrophoretic system for the isolation of human spermatozoa. Hum Reprod 20(8):2261-70.
5. Seli E, Gardner DK, Schoolcraft WB, Moffatt O, Sakkas D. 2004. Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization. Fertil Steril 82(2):378-83.
6. Tavalaee M, Razavi S, Nasr-Esfahani MH. 2009. Influence of sperm chromatin anomalies on assisted reproductive technology outcome. Fertil Steril 91(4):1119-26
7. Boitrelle F, Guthauser B, Alter L, Bailly M, Bergere M, Wainer R, Vialard F, Albert M, Selva J. 2014. High-magnification selection of spermatozoa prior to oocyte injection: Confirmed and potential indications. Reprod Biomed Online 28(1):6-13.
8. Tarozzi N, Nadalini M, Bizzaro D, Serrao L, Fava L, Scaravelli G, Borini A. 2009. Sperm-hyaluronan-binding assay: Clinical value in conventional IVF under italian law. Reprod Biomed Online 19 Suppl 3:35-43.
9. Evenson DP, Larson KL, Jost LK. 2002. Sperm chromatin structure assay: Its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques. J Androl 23(1):25-43.
10. Tarozzi N, Bizzaro D, Flamigni C, Borini A. 2007. Clinical relevance of sperm DNA damage in assisted reproduction. Reprod Biomed Online 14(6):746-57.
11. Cayli S, Sakkas D, Vigue L, Demir R, Huszar G. 2004. Cellular maturity and apoptosis in human sperm: Creatine kinase, caspase-3 and bcl-XL levels in mature and diminished maturity sperm. Mol Hum Reprod 10(5):365-72.
12. Said TM, Agarwal A, Zborowski M, Grunewald S, Glander HJ, Paasch U. 2008. Utility of magnetic cell separation as a molecular sperm preparation technique. J Androl 29(2):134-42.
Published
2018-11-14
Issue
Section
Review Article
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
