Lactate Levels As A Prognostic Indicator In Heterogeneous ICU Population

  • Mohamad Ommid Assistant Professor Post Graduate Department of Anaesthesiology Governement Medical College
  • Amina Khatoom Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
  • Sheikh Ishaq Department of Biochemistry Government Medical College Srinagar Jammu and Kashmir India
  • Reyaz Lone Department of Paediatric Surgery H.M.C Doha Qatar
  • Saba Ahad Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
  • Abraq Asma Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
  • Shahina Parveen Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
Keywords: APACHE, Lactate, In-hospital mortality, heterogeneous ICU population.

Abstract

Background: The period course of blood lactate levels could be supportive to evaluate a patient’s response to therapy. Serial blood lactate levels in different groups of acutely ill patients.Methods: A total of 200 patients admitted to ICU with critical illness were randomly selected for the study group, Relevant demographic information, clinical history, clinical and laboratory parameters including diagnosis and length of ICU stay were recorded from each patient. The first sample was taken on admission the other samples was taken on 2nd, 3rd and 4th day of admission. Serial arterial sample lactate measurement was done from the patients to note the initial level, time of maximal level and level at time to normal.Result: In the study population 27.5% belonged to the age group of 40-49 years followed by 24% in the age group 50-59 and 20.5% in 60-69 yrs. 57% patients were males and 43% were females. 20.5% patients expired 34.5% patients had hyperlactatemia during ICU stay out of which 31.9% patients expired.Conclusion: Elevated lactate is encountered in a multitude of clinical presentations. Hyperlactatemia is associated with an in-hospital mortality in a heterogeneous ICU population. Patients with elevated lactate levels predicted in hospital mortality and also normalization of lactate within 6 hours is associated with lower mortality. The observation of a better outcome associated with decreasing blood lactate concentrations was consistent throughout the clinical study. Lactate level is an easily measured laboratory parameter which can provide useful information for the bedside clinician when incorporated into the apt clinical milieu. DOI: 10.21276/AAMS.1743

Author Biographies

Mohamad Ommid, Assistant Professor Post Graduate Department of Anaesthesiology Governement Medical College
Assistant ProfessorPost Graduate Department of Anaesthesiology
Amina Khatoom, Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
Postgraduate Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
Sheikh Ishaq, Department of Biochemistry Government Medical College Srinagar Jammu and Kashmir India
Tutor/Demonstartor Department of Biochemistry Government Medical College Srinagar Jammu and Kashmir India
Reyaz Lone, Department of Paediatric Surgery H.M.C Doha Qatar
Assistant Consultant Department of Paediatric Surgery H.M.C Doha Qatar
Saba Ahad, Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
Lecturere Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
Abraq Asma, Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
Assistant Professor Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
Shahina Parveen, Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India
Associate Professor Department of Anesthesiology Government Medical College Srinagar Jammu and Kashmir India

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Published
2017-12-09
Section
Original Article