Primary Non Hodgkins Lymphoma Of Bilateral Breasts: A Rare Entity
Keywords:
breast, lymphoma, NHL
Abstract
Extranodal Non-Hodgkin's Lymphoma (NHL) of the breast is a rare entity, representing 0.04-1.1% of malignant tumours of the breast. Most breast lymphomas are the non-Hodgkin’s B cell type, with DLBCL being the most common. We present the case of a 32 years old female who presented with bilateral hard breast lumps, which were clinicoradiologically thought to be carcinomas. But on histopathology and immunohistochemistry, it was finally diagnosed as alymphoma. Primary and secondary lymphomas of the breast, though rare, should be considered in the differential diagnosis of breast malignancies. DOI: 10.21276/APALM.1335References
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12.Roberto G, Piccollo C, Rilke F. Primary Non Hodgkin's lymphoma of the female breast. Cancer. 1992;69:725-735.
2.Chakraborty J, Paul PC, Sarkar R, Rao RN. Primary non-Hodgkin's lymphoma of breast: a case report. Indian J PatholMicrobiol. 2007;50:315-317.
3.Shukla S, Awasthi NP, Singh P, Husain N. CD20 negative primary diffuse large B cell lymphoma of breast: Role of Pax-5. J Can Res Ther. 2015;11:658.
4.Nigam A, Singh AK, Singh SK, Singh N, Singh N, Sharma A. Primary Mammary (Non-Hodgkin) Lymphoma of Breast: A Case Report. J Cancer SciTher. 2011;3:173-175.
5.Cohen Y, Goldenberg N, Kasis S, Shpilberg D, Oren M. Primary breast lymphoma. Harefuah. 1993;125:24-26.
6.Jeon HJ, Akagi T, Hoshida Y, Hayashi K, Yoshino T,Tanaka T, et al. Primary non-Hodgkin malignant lymphoma of the breast. An immunohistochemical study of seven patients and literature review of 152 patients with breast lymphoma in Japan. Cancer. 1992; 70:2451-9.
7.Lamovec J, Wotherspoon A, Jacquemier J. Malignant lymphoma and metastatic tumours. In: Tavassoli FA, Devilee P, editors. World health organisation classification of tumors: pathology and genetics : tumours of the breast and female genital organs. Lyon: IARC; 2003.107-109.
8.Bobrow LG, Richard MA, Happerfield LC, Diss TC, Isaacson PG, Lammie GA, et al. Breast lymphomas: a clinicopathologic review. Hum Pathol. 1993;24:274-278.
9.Darnell A, Gallardo X, Sentis M, Castañer E, Fernandez E, Villajos M. Primary lymphoma of the breast: MR imaging feature. A case report.MagnReson Imaging. 1999;17:479-482.
10.Paulus DD. Lymphoma of the breast.RadiolClin North Am. 1990;28:833-840.
11.Hill QA, Owen RG. CNS prophylaxis in lymphoma: who to target and what therapy to use. Blood Rev. 2006;20:319–332.
12.Roberto G, Piccollo C, Rilke F. Primary Non Hodgkin's lymphoma of the female breast. Cancer. 1992;69:725-735.
Published
2017-10-19
Issue
Section
Case Report
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