Extranodal marginal zone lymphoma of mucosa associated lymphoid tissue arising in the pleura
Keywords:
Lymphoma, B-Cell, Marginal Zone, MALT Lymphoma
Abstract
A 77-year-old Haitian woman complained of two months history of cough and left upper quadrant abdominal pain. She had a remote history of tuberculosis that was treated back in Haiti many years ago. Imaging studies showed a left pleural effusion with posterior pleural thickening as well as lymphadenopathy in the left hilum and left supraclavicular area. The Pleural biopsy was consistent with extranodal marginal zone lymphoma of mucosa associated lymphoid tissue (EMZL/MALT). The supraclavicular lymph node also showed partial involvement by EMZL/MALT but was largely effaced by non-necrotizing granulomatous inflammation. Culture from this lymph node grew Mycobacterium tuberculosis complex. Primary pleural lymphoma is a rare entity and to the best of our knowledge only ten cases of pleural EMZL/MALT have been reported.We report a new case and a review of literature.References
1. King RM, Pairolero PC, Trastek VF, et al., Primary chest wall tumors: factors affecting survival. Ann Thoracic Surg. 1986; 41(6), 597-601.
2. Chen YB, Rahemtullah A, Hochberg E. Primary Effusion Lymphoma. The Oncologist. 2007; 12(5), 569- 76.
3. Nkatsuka SI, Yao M, Hoshida Y, Yamamoto S, Luchi K, Aozasa K. Pyothorax-associated Lymphoma: A Review of 106 Cases. Journal of Clinical Oncology. 2002; 20(20), 4255- 60.
4. Issacson P G, Chott A, Nakamura S, Muller-Hermelink H K, Harris N L, Swerdlow S H. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue (IARC WHO Classification of Tumours). s.l. : The International Agency for Research on Cancer. 2008: 214
5. Vega F, Padula A, Valbuena J R, Stancu M, Jones D, Medeiros L J. Lymphoma Involving the Pleura: A Clinicopathologic study of 34 Cases Diagnosed by Pleural Biopsy. Arch Pathol Lab Med. 2006; 130 (10), 1497- 502.
6. Kodama K, Yokose T, Takahashi K, Minami H, Nagai K, Matsuno Y, et al. Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue in the lung: a report of a case with pleural dissemination. Lung Cancer. 1999; 24, 175- 8.
7. Ahmad H, Pawade J, Falk S, Morgan J A, Balacumaraswami L. Primary pleural lymphomas. Thorax, 2003; 58, 908- 9.
8. Gomyo H, Kajimoto K, Maeda A, Mizuno I, Funada Y, Koizumi T, Fukui E, Hanioka K, Ogura M, Murayama T. t(14;18)(q32;q21)-bearing pleural MALT lymphoma with IgM paraproteinemia: Value of detection of specific cytogenetic abnormalities in the differential diagnosis of MALT lymphoma and lymphoplasmacytic lymphoma. Hematology. 2007;12(4), 315- 8.
9. Nakarsuka S I, Nagano T, Kimura H, Hanada S, Inoue H, Iwata T. Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type arising in the pleura with pleural fibrous plaques in a lathe worker. Annals of Diagnostic Pathology. 2012; 16(3), 224- 9.
10. Hirai S, Hamanaka Y, Mitsui N, Morifuji J, Sutoh M. Primary Malignant Lymphoma Arising in the Pleura without Preceding Long-standing Pyothorax. Ann Thorac Cardiovasc Surg. 2004; 10(5), 297-300.
11. Mitchell A, Meunier C, Ouellette D, Colby T. Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue With Initial Presentation in the Pleura. Chest. 2006; 129(3), 791- 4.
12. Kawahara K, Sasada S, Nagano T, Suzuki H, Kobayashi M, Matsui K, Takata K, Yoshino T, Michida T, Iwasaki T. Pleural MALT Lymphoma diagnosed on thoracoscopic resection under local anesthesia using an insulation-tipped diathermic knife. Pathology International. 2008; 58(4), 253- 6.
13. Motta G, Conticello C, Amato G, Moschetti G, Colarossi C, Cosentino S, et al. Pleuric presentation of extranodal marginal zone lymphoma of mucosa-associated lymphoid tisse: a case report and a review of the literature. 2010; 92(2), 369- 73.
14. Barahona M L, Duenas V P, sanchez M T, Plaza B V. Primary mucosa-associated lymphoid tissue lymphoma as a pleural mass. The British Journal of Radiology. 2011; 84(1008), e229-e231.
2. Chen YB, Rahemtullah A, Hochberg E. Primary Effusion Lymphoma. The Oncologist. 2007; 12(5), 569- 76.
3. Nkatsuka SI, Yao M, Hoshida Y, Yamamoto S, Luchi K, Aozasa K. Pyothorax-associated Lymphoma: A Review of 106 Cases. Journal of Clinical Oncology. 2002; 20(20), 4255- 60.
4. Issacson P G, Chott A, Nakamura S, Muller-Hermelink H K, Harris N L, Swerdlow S H. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue (IARC WHO Classification of Tumours). s.l. : The International Agency for Research on Cancer. 2008: 214
5. Vega F, Padula A, Valbuena J R, Stancu M, Jones D, Medeiros L J. Lymphoma Involving the Pleura: A Clinicopathologic study of 34 Cases Diagnosed by Pleural Biopsy. Arch Pathol Lab Med. 2006; 130 (10), 1497- 502.
6. Kodama K, Yokose T, Takahashi K, Minami H, Nagai K, Matsuno Y, et al. Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue in the lung: a report of a case with pleural dissemination. Lung Cancer. 1999; 24, 175- 8.
7. Ahmad H, Pawade J, Falk S, Morgan J A, Balacumaraswami L. Primary pleural lymphomas. Thorax, 2003; 58, 908- 9.
8. Gomyo H, Kajimoto K, Maeda A, Mizuno I, Funada Y, Koizumi T, Fukui E, Hanioka K, Ogura M, Murayama T. t(14;18)(q32;q21)-bearing pleural MALT lymphoma with IgM paraproteinemia: Value of detection of specific cytogenetic abnormalities in the differential diagnosis of MALT lymphoma and lymphoplasmacytic lymphoma. Hematology. 2007;12(4), 315- 8.
9. Nakarsuka S I, Nagano T, Kimura H, Hanada S, Inoue H, Iwata T. Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type arising in the pleura with pleural fibrous plaques in a lathe worker. Annals of Diagnostic Pathology. 2012; 16(3), 224- 9.
10. Hirai S, Hamanaka Y, Mitsui N, Morifuji J, Sutoh M. Primary Malignant Lymphoma Arising in the Pleura without Preceding Long-standing Pyothorax. Ann Thorac Cardiovasc Surg. 2004; 10(5), 297-300.
11. Mitchell A, Meunier C, Ouellette D, Colby T. Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue With Initial Presentation in the Pleura. Chest. 2006; 129(3), 791- 4.
12. Kawahara K, Sasada S, Nagano T, Suzuki H, Kobayashi M, Matsui K, Takata K, Yoshino T, Michida T, Iwasaki T. Pleural MALT Lymphoma diagnosed on thoracoscopic resection under local anesthesia using an insulation-tipped diathermic knife. Pathology International. 2008; 58(4), 253- 6.
13. Motta G, Conticello C, Amato G, Moschetti G, Colarossi C, Cosentino S, et al. Pleuric presentation of extranodal marginal zone lymphoma of mucosa-associated lymphoid tisse: a case report and a review of the literature. 2010; 92(2), 369- 73.
14. Barahona M L, Duenas V P, sanchez M T, Plaza B V. Primary mucosa-associated lymphoid tissue lymphoma as a pleural mass. The British Journal of Radiology. 2011; 84(1008), e229-e231.
Published
2015-05-05
Issue
Section
Case Report
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).
