HIV seropositivity and Neoplasms with plasma cell morphology: Plasmablastic lymphoma and Plasma cell myeloma : Is it a chance association or an increasing occurrence?

  • Anupama Praveen Gupta Government Medical College, Nagpur, India
  • Dinkar T Kumbhalkar Government Medical College, Nagpur
  • Sanjay Nanaji Parate Government Medical College, Nagpur
  • Shirish M Kawthalkar Government Medical College, Nagpur
  • Suprita Nayak Government Medical College, Nagpur
  • Purnima M Kodate Government Medical College, Nagpur
  • Nitin Shende Government Medical College, Nagpur
  • Ganesh Hake Government Medical College, Nagpur
Keywords: Plasma cell neoplasm, HIV seropositivity, Plasmablastic lymphoma

Abstract

Plasma cell tumors have shown an increased incidence in Human Immuno Deficiency Virus (HIV) positive patients. Plasma cell tumors in these patients occur in a younger age group than that in the general population, present at unusual sites and progress rapidly to involve multiple sites, including the soft tissues and viscera. Pathologically, many of these tumors show plasmablastic morphology. We present here six interesting cases of plasma cell tumor in HIV seropositive patients diagnosed on fine needle aspiration cytology (FNAC) and confirmed on histopathology and immunohistochemistry. These lesions presented at unusual locations like subcutaneous, oral and nasal. They presented at younger age, had aggressive behavior and unusual cytomorphology.

Author Biographies

Anupama Praveen Gupta, Government Medical College, Nagpur, India
Assistant professor in Pathology, Govt Medical college, nagpur, India
Dinkar T Kumbhalkar, Government Medical College, Nagpur
Professor and Head, Government Medical College, Nagpur
Sanjay Nanaji Parate, Government Medical College, Nagpur
Associate Professor, Government Medical College, Nagpur
Shirish M Kawthalkar, Government Medical College, Nagpur
Associate Professor, Government Medical College, Nagpur
Suprita Nayak, Government Medical College, Nagpur
Assistant Professor , Government Medical College, Nagpur
Purnima M Kodate, Government Medical College, Nagpur
Assistant Professor , Government Medical College, Nagpur
Nitin Shende, Government Medical College, Nagpur
Assistant Professor , Government Medical College, Nagpur
Ganesh Hake, Government Medical College, Nagpur
Post graduate student, Government Medical College, Nagpur

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Published
2015-05-10
Section
Case Report

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