A Study on Diagnostic Accuracy of Cervical Pap Smear by Correlating with Histopathology in a Tertiary Care Centre
Keywords:
Cervical Pap, Smear, Sensitivity, Specificity, Diagnostic Accuracy
Abstract
Objective: Analysis of various lesions detected on Cervical Pap smears and correlate it with histopathology to detect the diagnostic accuracy of Pap smears in detection of cervical lesions. Methodology: The present study is a prospective study conducted from December 2015 to May 2017 for a period of 18 months which included 83 cases. All these patients underwent screening procedure with cervical smears and were directed for colposcopic guided biopsy. Results: In the present study Pap smears showed sensitivity of 96.42%, specificity of 70.37%and diagnostic accuracy of 87.95 %. Conclusion: Pap smear being minimally invasive showed significant correlation with Colposcopic directed biopsy. Pap smear still remains ideal screening procedure for early detection of cervical lesions.References
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9.Ashmita D, Shakuntala PN, Rao Sr, Sharma SK, Geethanjali S. Comparison and correlation of
Pap smear, Colposcopy and histopathology in symptomatic women and suspicious looking
cervix in tertiary hospital care centre. Int J Health Sci Res. 2013;3:50-9
10.Malur PR, Desai BR, Naita D, Geeta D, Bhavana S, Pallavi G. Sequential screening with
cytology and colposcopy in detection of cervical neoplasia. J South Asian Feder Obst Gynae
2009;1:45-8.
11.Jain V, Vyas AS. Cervical Neoplasia-CytoHistological Correlation (Bethesda System) A
Study of 276 Cases. J Cytol Histol 2010;1:106.
cervix by cytology, colposcopy and histopathology in women of rural areas. Int J Reprod
Contracept Obstet Gynecol 2014;3:213-8.
2.Saha R, Thapa M. Correlation of cervical cytology with cervical histology. Kathmandu Univ
Med J Cytol Histol 2010;3:222-4.
3.Malpani G et al. Cervical Pap smear study and detection of abnormal epithelial lesions and
determination of its accuracy by cytohistological correlation in patients of tertiary care
teaching hospital in central India. Int J Reprod Contracept Obstet Gynecol 2016;5(7):2312-
16.
4.Barut MU, Kale A, Kuyumcuoglu U, Bozkurt M, Agacayak E, Ozekinci S et al. Analysis of
Sensitivity, Specificity and Positive and Negative Predictive Values of Smear and Colposcopy
in Diagnosis of Premalignant and Malignant Cervical lesions Med Sci Monit 2015;21:3860-7
5.Krishnegowda S, Veena MS. Efficacy of colposcopy technique with Pap smear and histology
in screening of cervical lesions. Int J Reprod Contracept Obstet Gynecol 2014;3(3):696-702.
6. Witkiewicz AK, Wright TC, Ferenczy A, Ronnett BM, Kurman RJ. In: Kurman RJ, Ellenson
LH, Ronette BM, editors. Blaustein‟s Pathology of the Female Genital Tract. 6th ed. New
York: Springer; 2011:253-95
7. Kurman RJ, Carcangiu ML, Herrington CS, Young RH, editors. WHO Classification of
Tumors of Female Reproductive Organs. 4th ed. Lyon: IARC 2014: 169-206.
8.Algotar K, Nalwade A, Sachdev S. Predictive value of colposcopy in cervical cancer screening.
Bombay Hosp J 2004;4603:1-9.
9.Ashmita D, Shakuntala PN, Rao Sr, Sharma SK, Geethanjali S. Comparison and correlation of
Pap smear, Colposcopy and histopathology in symptomatic women and suspicious looking
cervix in tertiary hospital care centre. Int J Health Sci Res. 2013;3:50-9
10.Malur PR, Desai BR, Naita D, Geeta D, Bhavana S, Pallavi G. Sequential screening with
cytology and colposcopy in detection of cervical neoplasia. J South Asian Feder Obst Gynae
2009;1:45-8.
11.Jain V, Vyas AS. Cervical Neoplasia-CytoHistological Correlation (Bethesda System) A
Study of 276 Cases. J Cytol Histol 2010;1:106.
Published
2018-05-21
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Original Article
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