Extra medullary myeloid cell tumor: A Case Report
Keywords:
Extra medullary, Myeloid cell tumor, Acute myeloid leukemia, Parotid swelling
Abstract
Extra medullary myeloid cell tumors or granulocytic sarcomas or chloromas represents a localised tumor of myeloblasts or monoblasts infiltrating extramedullary sites. The term is used for any solid collection of leukemic cells in the extra haematopoietic sites. There have been reports of these tumors occurring concomitantly with, after, or rarely prior to the onset of leukemia. We present a case of a child presented with swelling in the right parotid region, which was diagnosed as chloroma on fine needle aspiration cytology. Further confirmation was done on peripheral blood and bone marrow evaluation.References
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2. Pileri SA, Ascani S, CoxMc, et al . Myeloid Sarcoma:clinico-Pathologic phenotypic and cytogenetic analysis of 92 adult patients. Leukemia 2007; 21 :340-350.
3. Wiernick PH. Extramedullary manifestations of adult leukemia. Am CancerSociety atlas of clinical oncology adult leukemias. London: BC Decker, 2001: 275-305.
4. Baer MR. Management of unusual presentations of acute leukemia. Haematol/ Oncol Clin North Am 1993; 7:275-292.
5. Robert E. Hutchison, Frederick R. Davey. Leucocytic disorders, 20th ed, John Bernard Henry, Fredrick R. Davey, Chester J. Herman et al, Philadelphia, WB Saunders, 2001, 600-601.
6. Alan K Burnett. Acute myeloid leukemia, 5th ed, A Victor Hoffbrand, Daniel Catovsky, Edward GD. Tuddenha , Blackwell, Oxford, 2005, 510-511.
7. Jaffe ES, Harris NL, Stein H, Vardimann JW, World Health Organisation Classification of Tumours-Tumours of Haematopoietic and Lymphoid Tissues. 2001,105.
8. Suzner T, Colakoglu N, Cirak B, Keskin A, et al. Intracerebellar granulocytic sarcoma complicating acute myelogenous leukemia: a case report and review of the literature. J Clin Neurosci.2004;11:914-917.
9. Imrie K, Koovacs M, Selby D, et al. Isolated chloroma- the effects of early antileukemic therapy. Ann Intern Med.1995; 123:351-353.
10. D’Costa GF, Hastak MS, Patil YV. Granulocytic sarcoma of breast: an aleukemic presentation. Indian J Med Sci. 2007; 61;152-5.
11. Tanravahi R, Qumsiyeh M, Patil S. Extra medullary leukemia adversely affects hematologic complete remission and overall survival in patients with t(8;21)(q22;q22): Results from Cancer and Leukemia Group B 8461. J Clin Oncol.1997; 15:466.
Published
2015-05-10
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Section
Case Report
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