Krukenberg tumor arising from bilateral lobular carcinoma, in a pregnant lady: a rare case report
Keywords:
Krukenberg tumor, Pregnancy, Breast, Invasive Lobular carcinoma, IHC, Ovary
Abstract
Metastatic ovarian tumors are thought to account for approximately 10–30% of malignant ovarian tumors. Krukenberg tumor refers to a malignancy in the ovary that metastasized from a primary site, classically the gastrointestinal tract, although it can arise in other tissues such as the breast (approx. 04%). Krukenberg tumor during pregnancy arising from breast is even rarer (0.1 - 0.2%). The presence of adnexal masses during pregnancy ranges from 1:81 to 1:2,500 pregnancies, but only 3% of these masses are malignant. Management of such cases can present as diagnostic & treatment dilemma. We report a case of 25 year primiparous female with Krukenberg tumor of breast origin.References
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2. Osama M. Al-Agha, Anthony D. Nicastri. An in-depth look at Krukenberg tumor: An overview. Arch Pathol Lab Med 2006;130:1725–1730.
3. Yada-Hashimoto N, Yamamoto T, Kamiura S, Seino H, Ohira H, Sawai K, et al. Metastatic ovarian tumors: a review of 64 cases. Gynecol Oncol 2003; 89:314-317.
4. H Y Kwon, E Nam, S W Kim,Y T Kim. A young patient in Korea with Krukenberg tumors arising from breast cancer: A case report. Korean J Obstet Gynecol 2011;54(10):643-646.
5. O F D Garcia, M D Sotomayor, C Chanana. Bilateral ovarian krukenberg tumor in a full-term pregnancy. ISRN Obstetrics and Gynecology 2011; 45: 450-51.
6. F. Krukenberg, “Uber das fibrosarcoma ovarii mucocellulase (carcinomatoses),” Archives of Gynecology and Obstetrics, vol.50, pp. 287–321, 1896.
7. Gagnon Y, Tetu B. Ovarian metastases of breast carcinoma. A clinicopathologic study of 59 cases. Cancer 1989;64: 892–98.
8. Kiyokawa T, Young RH, Scully RE. Krukenberg tumors of the ovary: a clinicopathologic analysis of 120 cases with emphasis on their variable pathologic manifestations. Am J Surg Pathol 2006;30: 277–99.
Published
2015-05-10
Issue
Section
Case Report
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