Causes of Sudden Natural Death in Adults: A Retrospective Study from Malatya Province, Turkey
Keywords:
Sudden natural death, autopsy, ischemic heart disease, Turkey
Abstract
Background: This study’s goal is to determine the incidence of sudden natural death (SND) based on adult forensic autopsies performed in the Turgut Özal Medical Center Research Hospital, its age and gender distribution, and its causes and to evaluate histopathological results from the organs.Methods: Forensic autopsies from the last 1.5 years were examined retrospectively. Cases of sudden natural death over the age of 15 years were included. The ages and genders of the cases were recorded. Hematoxylin-Eosin stained preparations of organs were examined. The histopathological findings of the heart, lung, liver, kidney, and brain were evaluated.Conclusions: Sudden natural death was more common in older males. The most common cause was ischemic heart disease. Other causes included non-ischemic heart disease, respiratory system disease, central nervous system disease, gastrointestinal system disease, and urogenital system disease.References
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21. Escoffery CT, Shirley SE. Causes of sudden natural death in Jamaica: a medicolegal (coroner’s) autopsy study from the University Hospital of the West Indies. Forensic Sci Int. 2002; 129: 116-21.
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26. Amakiri CNT, Akang EEU, Aghadiuno PU, Odesanmi WO. A prospective study of coroner’ autopsies in University College Hospital, Ibadan, Nigeria. Med Sci Law. 1997; 37: 69-75.
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28. DiMaio WJ, DiMaio D. Forensic pathology. 2nd ed. London, New York, Washington: CRC Press; 2001.
29. Simpson K, Knight B. Forensic medicine. 11th ed. London: Hodder Arnold Publication; 1997.
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2. Spivak J, Verdain B. Manuel of Clinical Problems in İnternal Medicine 3 th ed, pp. 1982; 356-9.
3. Soysal Z, Eke SM, Çağdır AS. Doğal Nedenlere Bağlı Ani Ölümler. Adli Otopsi. İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Yayınları; 1999.
4. Virmani R, Burke AP, Farb A (2001). Sudden cardiac death. Cardiovas Pathol. 2001; 10: 211-18.
5. Luqman M, Sattar A, Abbasi S, Satti TM. Pattern of sudden deaths in armed forces personnel - posmortem study. Pak Armed Forces Med J. 1995; 45: 66-71.
6. Hort W. Arteriosclerosis. Its morphology in the past and today. Basic Res Cardiol. 1994; 89: 1-15.
7. Stary HC, Chandler AB, Glagov S, et al (1994). A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Arterioscler Thromb. 1994; 14: 840-856.
8. Spooner PM, Priori SG, Myerburg RJ. Spotlight on sudden cardiac death. Cardiovasc Res 2001; 50: 173-6.
9. Polat O, Akça S, Günhan Ö, Finci R. Doğal Kökenli Ani Ölümler. Adli Tıp Derg. 1989; 5: 165-9.
10. Tunstall-Pedoe H, Kuulasmaa K. Amouyel P. et al. Myocardial infarction and Coronory deaths in the World Health Organization MONICA Project registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents. Circulation. 1994; 90: 583-612.
11. Virmani R. Burke AP and Farb A. Sudden cardiac death. Cardiovasc Pathol. 2001; 10: 275-282.
12. Ezra A. Cardiology Clin. 1987; 5: 337-343.
13. DiMaio WJ, DiMaio D. Deaths Due to Natural Disease. Forensic Pathology. 2 nd ed, New York: CRC press; 2001. 43-46.
14. Dinesh S Rao, Yadhukul. Sudden and Unexpected Natural Deaths-A-Four-Year Autopsy Review. JPAFMAT. 2008; 8(2).
15. Bruce F, Waller A. Postgr, Med. 1998; 83: 273-282.
16. Anderson R E, Hill RB, Broudy DW, Key CR and Pathak D. A population based autopsy of Sudden, Unexpected deaths from Natural causes among persons 5 to 39 yrs old during a 12 year period. Human Pathol. 1994; 25: 1332-40.
17. Kong MH, Fonarow GC, Peterson ED, et al. Systematic review of the incidence of sudden cardiac death in the United States. J Am Coll Cardiol. 2011; 57: 794-801.
18. Saukko P, Knight B. Knight’s forensic pathology. 3rd ed, London: Arnold; 2004.
19. Virmani R, Burke AP, Farb A. Sudden cardiac death. Cardiovasc Pathol. 2001; 10: 211-8.
20. Orlandi A, Bochaton Piallat ML, Gabbiani G, Spagnoli LG. Aging, smooth muscle cells and vascular pathobiology: implications for atherosclerosis. Atherosclerosis. 2006; 188: 221-30.
21. Escoffery CT, Shirley SE. Causes of sudden natural death in Jamaica: a medicolegal (coroner’s) autopsy study from the University Hospital of the West Indies. Forensic Sci Int. 2002; 129: 116-21.
22. Puranik R, Chow CK, Duflou JA, Kilborn MJ, McGuire MA. Sudden death in the young. Depart of Cardiol. 2005; 447: 742-6.
23. Yilmaz R, Yuksekbas O, Erkol Z, Bulut ER, Arslan MN. Postmortem findings after anaphylactic reactions to drugs in Turkey. Am J Forensic Med Pathol. 2009; 30: 346-9.
24. Puranik R, Chow CK, Duflou JA, Kilborn MJ, McGuire MA. Sudden death in the young. Heart Rhythm. 2005; 2: 1277-82.
25. Vanbrabant P, Dhondt E, Sabbe M. What do we know about patients dying in the emergency department? Resuscitation. 2004; 60: 163-70.
26. Amakiri CNT, Akang EEU, Aghadiuno PU, Odesanmi WO. A prospective study of coroner’ autopsies in University College Hospital, Ibadan, Nigeria. Med Sci Law. 1997; 37: 69-75.
27. Hoek JB, Pastorino JG (2004). Cellular signaling mechanisms in alcohol-induced liver damage. Semin Liver Dis. 2004; 24: 257-72.
28. DiMaio WJ, DiMaio D. Forensic pathology. 2nd ed. London, New York, Washington: CRC Press; 2001.
29. Simpson K, Knight B. Forensic medicine. 11th ed. London: Hodder Arnold Publication; 1997.
30. Kunin CM. Does kidney infection cause renal failure? Annu Rev Med. 1985; 36: 165-76.
31. Cheung CM, Ponnusamy A, Anderton JG. Management of acute renal failure in the elderly patient: a clinician's guide. Drugs Aging. 2008; 25: 455-76.
Published
2018-05-19
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Section
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