Incidental Presentation of Microfilaria in Cytological Smears at Different Sites with Coexisting Unusual Pathology
Keywords:
Microfilaria, waucheria bancrofti, FNAC.
Abstract
Background: Microfilaria is a major public health problem in tropical and subtropical countries. Wuchereria bancrofti is the most common filarial infection. Despite its high incidence it is unusual to find microfilaria in fine needle aspiration cytology (FNAC) smear and body fluids. Out of these very few cases reported of coexisting microfilaria with neoplasm in the cytology. In literature however role of Microfilaria in tumorogenesis is controversial and not proven yet. The Aim of this study was showing importance of cytology (FNAC) in diagnosis of filariasis in lesions clinically anticipated to be of neoplastic /benign and to review the cytomorphology of bancroftian filaria and its association with neoplasm. Methods: This is a retrospective study carried out in department of Pathology in T. S. Misra medical College and Hospital, Lucknow. Cytological records from last one year from December 2016 to November 2017 were taken of FNAC from different swelling, body fluids and screen for filariasis and its association with neoplasm. Results: Out of 510 cases 17 cases showed microfilaria. Out of 17 cases 04 cases associated with malignant cells and remaining 13 cases with benign lesion. Conclusion: Despite high incidence of filariasis, microfilaria in FNAC is not a very common finding. As a consequence, careful screening of cytological smear can be definitive diagnosis of early, asymptomatic and clinically unanticipated cases of bancroftian filariasis.References
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8. Pantola C., Kala S., Agarwal A., Khan L. Microfilaria in cytological smears at rare sites coexisting with unusual pathology: A series of seven cases. Trop. Parasitol. 2012;2(1):61-63
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10. Reddy GS, Balasundaram S. Filarial pericardial effusion. J Indian Med Assoc. 1977;68:125–6.
11. Andola S, Naik A. Microfilaria and filarial granulomas from fine niddleaspirates . A study of 25 cases. Southeast Asian J Trop Med Public Health . 2011; 42(6): 1351-1358.
12. Alam K. Navaz, Madhusudan P. Raikar, Vishak Acharya, and Sanmath K. Shetty. Pleural effusion: An unusual cause and association. Lung India.2013;2(30):158-160.
13. Katti TV, Athanikar VS, Ananthrao AS, Rathod CV. Cytodiagnosis of microfilarial lymphadenitis coexistent with metastatic squamous cell carcinoma in a left cervical lymph node: An unusual presentation. Ann Nigerian Med 2012;6:47-9.
14. Gupta S, Gupta R, Bansal B, Singh S, Gupta K, Kudesia M. Significance of incidental detection of filariasis on aspiration smears: a case series. Diagn Cytopathol 2010;38(7):517-20.
2. Yenkeshwar PN, Kumbhalkar DT, Bobhate SK. Microfilariae in fine needle aspirate: A report of 22 cases. Indian J Pathology & Microbiology. 2006;49:365–69. [PubMed]
3. Chakrabarti N, Konar K, Mala, Bandyopadhyay A, Bose K. Incidental Detection of Microfilaria in Cytology: Report of three Cases. Ann Clin Pathol. 2014;2(4):1033.
4. Nutman Thomas B, Weller Peter F. Filarial and related Infections: Harrison’s Principles of Internal Medicine. 16th Edition. Vol. 1. McGraw Hill; pp. 1260–63.
5. Park K. Lymphatic Filariasis: Park's textbook of preventing and social medicine. 22nd Edition.Jabalpur: Banarasidas Bhanot; 2013. pp. 245–50.
6. Varghese R, Raghuveer CV, Pai MR, Bansal R. Microfilariae in cytologic
smears: A report of six cases. ActaCytol. 1996;40:299-301.
7. Muddamwar VG., Rane MS., Shewale SP., Sameer MA., Deshpande M. S., Phasge G. Midarm lymphadenopathy – A rare presentation of filariasis in a 20 year old female in Nanded Region. International Journal of Pharmaceutical Science Invention. May 2014; 3(5):12-16
8. Pantola C., Kala S., Agarwal A., Khan L. Microfilaria in cytological smears at rare sites coexisting with unusual pathology: A series of seven cases. Trop. Parasitol. 2012;2(1):61-63
9. Mitra SK, Mishra RK, Verma P. Cytological diagnosis of microfilariae in filariasis endemic areas of eastern Uttar Pradesh.J Cytol. 2009;26(1):11-14.
10. Reddy GS, Balasundaram S. Filarial pericardial effusion. J Indian Med Assoc. 1977;68:125–6.
11. Andola S, Naik A. Microfilaria and filarial granulomas from fine niddleaspirates . A study of 25 cases. Southeast Asian J Trop Med Public Health . 2011; 42(6): 1351-1358.
12. Alam K. Navaz, Madhusudan P. Raikar, Vishak Acharya, and Sanmath K. Shetty. Pleural effusion: An unusual cause and association. Lung India.2013;2(30):158-160.
13. Katti TV, Athanikar VS, Ananthrao AS, Rathod CV. Cytodiagnosis of microfilarial lymphadenitis coexistent with metastatic squamous cell carcinoma in a left cervical lymph node: An unusual presentation. Ann Nigerian Med 2012;6:47-9.
14. Gupta S, Gupta R, Bansal B, Singh S, Gupta K, Kudesia M. Significance of incidental detection of filariasis on aspiration smears: a case series. Diagn Cytopathol 2010;38(7):517-20.
Published
2018-07-23
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