Infarcted Fibroadenoma: An unusual case with its Cyto-histopathological Correlation

  • Nehal Ahmad Hamdard Institute of Medical Siences & Research,Hamadard Nagar,New Delhi-110062
  • Mohd. Jaseem Hassan Hamdard Institute of Medical Siences & Research,Hamadard Nagar,New Delhi-110062
  • Shaan Khetrapal Modi Hamdard Institute of Medical Siences & Research,Hamadard Nagar,New Delhi-110062
  • Sabina Khan Hamdard Institute of Medical Siences & Research,Hamadard Nagar,New Delhi-110062
  • Sujata Jetley Hamdard Institute of Medical Siences & Research,Hamadard Nagar,New Delhi-110062
Keywords: Breast, Fibroadenoma, Infarction, Necrosis

Abstract

Fibroadenoma is a benign breast lesion of adolescents and young women. It constitutes 20 % of all benign breast tumours. Fibroadenoma is associated with many secondary changes like calcification, ossification, hyalinization, myxoid and apocrine squamous metaplasia. Spontaneous infarction in fibroadenoma is very rarely seen. We report one such case of spontaneous infarction of fibroadenoma in a 16 year old unmarried female with its cyto-histopathological correlation, that posed us with diagnostic dilemma in early stage. The possibility of this entity should be considered while diagnosing the breast lumps on cytology. The esion was further confirmed on histology.

Author Biographies

Nehal Ahmad, Hamdard Institute of Medical Siences & Research,Hamadard Nagar,New Delhi-110062
Department - PathologyMD , Demonstrator
Mohd. Jaseem Hassan, Hamdard Institute of Medical Siences & Research,Hamadard Nagar,New Delhi-110062
PathologyAssociate Professor
Shaan Khetrapal Modi, Hamdard Institute of Medical Siences & Research,Hamadard Nagar,New Delhi-110062
PathologyAssistant Professor
Sabina Khan, Hamdard Institute of Medical Siences & Research,Hamadard Nagar,New Delhi-110062
PathologyAssociate Professor
Sujata Jetley, Hamdard Institute of Medical Siences & Research,Hamadard Nagar,New Delhi-110062
PathologyProfessor

References

1. Tavassoli F.A. 2nd ed. McGraw Hill; New York, NY: 1999. Pathology of the Breast; pp. 571–579.
2. Toy H, Esen HH, Sonmez FC, Kucukkartallar T. Spontaneous Infarction in a Fibroadenoma of the Breast. Breast Care (Basel) 2011;6(1):54–55.
3. Demetrakopoulos NJ. Three dimensional reconstruction of a human mammary Fibroadenoma. Quaterly bulletin of Northwestern University Medical school 1958;32:221-228
4. Hughes LE, Mansel RE and Webster DJT (1989) Fibroadenoma and related tumours Benign Disorders and Diseases of the Breast, ed LE Hughes, RE Mansel and DJT Webster (London: Bailliere Tindall) pp 59–73
5. Delarue J, Redon H. Myocardial fibro-adenoma breast; clinical problem and pathogenesis. Sem Hop 1949; 25:2991-6.
6. Fowler CL. Spontaneous infarction of fibroadenoma in an adolescent girl. Pediatr Radiol. 2004;34:988–90.
7. Skenderi F, Krakonja F, Vranic S. Infarcted fibroadenoma of the breast: report of two new cases with review of the literature. Diagn Pathol. 2013 Feb 27;8:38
8. McCutcheon JM, Lipa M. Infarction of a fibroadenoma of breast following fine needle aspiration. Cytopathology 1993;4:247-50.
9. Fadaei-Araghi M, Geranpayeh L, Irani S, Matloob R, Kuraki S. Breast tuberculosis: Report of eight cases. Arch Iran Med. 2008; 11:463-5.
10. Javadzadeh B, Finley J, Williams HJ. Fine needle aspiration cytology of mammary duct ectasia: Report of a case with novel cytologic and immunocytochemical findings. Acta Cytol. 2001; 45:1027-31.
11. Deshpande KM, Deshpande AH, Raut WK, Lele VR and Bobhate SK. Diagnostic difficulties in spontaneous infarction of a fibroadenoma in an adolescent: case report Diagn Cytopathol 2002; 26:26–8 DOI: 10.1002/dc.10029
Published
2018-09-17
Section
Case Report