Extrasellar Sphenoid Sinus Pituitary Adenoma
A Case Report
Keywords:
Chromophobe adenoma, Invasive pituitary adenoma, Ectopic sphenoid sinus Pituitary adenoma
Abstract
Pituitary tumors are usually benign adenomas presenting as space occupying lesions in the sella turcica. Rarely these tumors may present beyond the sella either as an extension of the primary tumor or tumor arising from an aberrant pituitary location. One such extra sellar extension or origin of these tumors is in the olfactory spaces, comprising of 2% of all the nasal tumor. Because of the rarity of lesion and sometimes nonfunctional nature of the tumor, these may present diagnostic problems to the otolaryngologists and are diagnosed as polyps or nasopharyngeal malignant tumors. Measurement of pituitary hormones may provide a clue to the diagnosis in cases of paranasal polyps or rhinorrhea as it may change the management in such cases. We present here a case of a patient with an invasive pituitary adenoma who had presented in the Department of Otorhinolaryngology with epistaxis.References
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2. Dent JA, Rickhuss PK. Invasive pituitary adenoma presenting with nasal obstruction. J Laryngol Otol. 1989;103:605-9
3. Wenig BM, Heffess CS, Adair CF, et al. Ectopic pituitary adenomas (EPA): a clinicopathologic study of 15 cases. Mod Pathol 1995;8:56A.
4. Ectopic Sphenoid Sinus Pituitary Adenoma (ESSPA) with Normal Anterior Pituitary Gland: A Clinicopathologic and Immunophenotypic Study of 32 Cases with a Comprehensive review of the English Literature Head and Neck Pathol (2012) 6:75–100
5. Cushing HW. The Pituitary Body and Its Disorders, clinical states produced by disorders of hypohysis cerebri. Philadephia, London: J.B. Lippincott Company; 1912
6. Johnston PC, Courtney HC, Hunter SJ, Mc Cance DR. Macroprolactinomas presenting as nasal polyps: A series of three cases. Ir J Med Sci. 2012;181:277-9.
7. Van de Lely AJ, Knegt PP, Stefanko SZ, Tanghe HL, Singh R, Lamberts SW. Nasopharyngeal presentations of pituitary tumours. Differential diagnosis and treatment. J Clin Endocrinol Metab. 1992;74:811-3.
8. Giannou P, Kontogeorgos G, Elemenoglou J, Vamvassakis E, Rologis D, Orphanidis G. Pituitary adenoma with appearance of nassal polyp. Arch Pathol. 2001;35:727-32.
9. Ernesto P, Marco F-F, Vittorio S, Domenico S, Federico R, Dario S and Giorgio F. Ectopic TSH-secreting pituitary adenoma of the vomerosphenoidal junction. European Journal of Endocrinology (2003) 148 253–257
10. Luk IS, Chan JK, Chow SM, Leung S. Pituitary adenoma presenting as sinonasal tumor: Pitfalls in diagnosis. Hum Pathol. 1996;27:605-9
11. Ali R, Noma U, Jansen M, Smyth D. Ectopic pituitary adenoma presenting as midline nasopharyngeal mass. Ir J Med Sci.2010;179:593–5.
Published
2018-07-18
Issue
Section
Case Report
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