Primary Bone Lymphoma: Case Report and Review of Literature

  • Sunita Singh PT BDS PGIMS, Rohtak, Haryana, India
  • Yashika Bhatia PT BDS PGIMS, Rohtak, Haryana, India
  • Zile Singh PT BDS PGIMS, Rohtak, Haryana, India
  • Vipul Gupta PT BDS PGIMS, Rohtak, Haryana, India
  • Rajeev Sen PT BDS PGIMS, Rohtak, Haryana, India
Keywords: Primary bone lymphoma, extranodal lymphoma and precursor B cell lymphoblastic type

Abstract

Primary bone lymphoma (PBL) is a rare extranodal lymphoma accounting for less than 5% of all primary bone malignancies. Most of these lymphomas are of diffuse large cell type with age group of 20-50 years. We present a case of Primary bone lymphoma- precursor B cell lymphoblastic type in a paediatric female patient. Correct diagnosis is extremely important because PBL usually is curable in the pediatric age group with appropriate therapy.

References

1. Wu H, Bui M M, Leston D G, Shao H, Sokol L et al. Clinical Characteristics and Prognostic Factors of Bone Lymphomas: Focus on the Clinical Significance of Multifocal Bone Involvement by Primary Bone Large B-Cell Lymphomas. BMC Cancer 2014:900.
2. Singh T, Satheesh C T, Lakshmaiah K C, Suresh T M, Babu G K et al. Primary bone lymphoma: A report of two cases and review of the literature. J Can Res Ther 2010:296-8
3. Jain A, Alam K, Maheshwari V, Khan R, Nobin H, Narula V. Primary bone lymphomas—Clinical cases and review of literature. Journal of Bone Oncology. 2013;2:132-6.
4. Heyning FH, Hogendoorn PC, Kramer MH, Hermans J, Kluin Nelemans JC, Noordijk EM and Kluin PM: Primary non Hodgkin’s lymphoma of bone: a clinicopathological investi¬gation of 60 cases. Leukemia 1999:2094-8.
5. Zhou H Y, Gao F, Bu B, Fu Z, Sun X J, Huang C S et al. Primary bone lymphoma: a case report and review of the literature. Oncol. Lett. 2014:1551–6
6. Coley BL, Higginbotham NL, Groesbeck HP. Primary reticulum cell sarcoma of bone; summary of 37 cases. Radiology 1950:641-58.
7. Maruyama D, Watanabe T, Beppu Y, et al Primary bone lymphoma: a new and detailed characterization of 28 patients in a single-institution study. Jpn J Clin Oncol 2007:216–23.
8. Bhagavathi S, Fu K. Primary bine lymphoma. Arch Pathol Lab Med 2009:1868-71.
9. Qureshi, A., Ali, A., Riaz, N., Pervez, S. Primary non-Hodgkin’s lymphoma of bone: experience of a decade. Indian J Pathol Microbiol 2010:267–70.
10. Li X, Xu-Monette ZY, Yi S, et al. Primary Bone Lymphoma Exhibits a Favorable Prognosis and Distinct Gene Expression Signatures Resembling Diffuse Large B-Cell Lymphoma Derived From Centrocytes in the Germinal Center. Am J Surg Pathol 2017:1309.
Published
2018-10-26
Section
Case Report