A Cystic Granulosa Cell Tumor of Ovary: An Incidental Finding in a 50 years Old Lady

  • Padam Kumari Agarwal Vivekananda Polyclinic & Institute of Medical Sciences Lucknow India.
  • Nidhi Varshney VIVEKANANDA POLYCLINIC AND INSTITUTE OF MEDICAL SCIENCES
  • Shyam Kumar Maurya Vivekananda Polyclinic & Institute of Medical Sciences Lucknow India.
Keywords: Cystic granulosa cell tumour, Hormone producing neoplasms of ovary, Histomorphological features of granulosa cell tumour

Abstract

Granulosa cell tumours (GCTs) are rare ovarian sex cord stromal tumours. GCTs usually are oestrogen producing neoplasms and hence consequently, symptoms related to hyperestrogenism are common at the time of diagnosis. Here we document a case of cystic GCT that was incidentally discovered on histopathological examination. An abdominal hysterectomy was done for abnormal uterine bleeding in a 50 years old lady, clinically was thought to be due to uterine fibroid. A unilateral oophorectomy was also done due to a small cyst in the left ovary, which on histopathological examination revealed cystic granulosa cell tumour in the ovary. Equipped with this knowledge, a better clinical correlation with the presenting symptoms could be made in future by clinicians and pathologists. The final diagnosis may change the prognosis and also the future treatment plan.

Author Biography

Padam Kumari Agarwal, Vivekananda Polyclinic & Institute of Medical Sciences Lucknow India.
Sr. Consultant, Department of Pathology

References

1. Ukah CO, Ikpeze OC, Eleje GU, Eke AC. Adult granulosa cell tumor associated with endometrial carcinoma: A case report. J Med Case Rep. 2011;5:340.
2. Evans AT III, Gaffey TA, Malkasian GD Jr, Annegers JF. Clinicopathologic review of 118 granulosa and 82 theca cell tumors. ObstetGynecol 1980;55:231-8.
3. Kristin RR, William M; An unusual case of juvenile granulosa cell tumour of the ovary. Radiol Case Reports, 2009; 4(1): 178.
4. Lee IH, Choi CH, Hong DG, Song JY, Kim YJ, Kim KT, et al. Clinicopathologic characteristics of granulosa cell tumors of the ovary: A multicenter retrospective study. J GynecolOncol. 2011;22:188–95
5. Evans AT III, Gaffey TA, Malkasian GD Jr, Annegers JF; Clinicopathologic review of 118 granulosa and 82 theca cell tumors. ObstetGynecol, 1980; 55(2): 231-238.
6. Fox H, Agrawal K, Langley FA; A clinicopathologic study of 92 cases of granulosa cell tumor of the ovary with special reference to the factors influencing prognosis. Cancer, 1975; 35(1): 231-241.
7. Kandukuri M., Pandey V. Cystic granulosa cell tumor of the ovary- diagnosed on histopathology. Sch. Acad. J. Biosci., 2015; 3(6):522-525
8. Pectasides D, Pectasides E, Psyrri A. Tumor review, granulosa cell tumors of the ovary. Cancer treatment reviews 2008;34:1-12
9. Norris HJ, Zaloudek C. Granulosa cell tumors of the ovary: a clinical and pathologic study of 32 cases. Am J SurgPathol 1984;6:405.
10. Chua ISY, Tan KT, Lim-Tan SK, Ho TH. A clinical review of granulosa cell tumors of the ovary cases in KKH. Singapore Med J 2000;42:203-7.
Published
2018-11-29
Section
Case Report