A Study of Hematological Changes in Dengue Patients at A Tertiary Care Hospital, Bhavnagar, Gujarat

  • Vishva Narendrabhai Jethva Govt. Medical College, Bhavnagar, Gujarat, India
  • Mayuri Vasudevbhai Thaker Govt. Medical College, Bhavnagar, Gujarat, India
Keywords: Dengue fever, Thrombocytopenia, Leucopenia


Background: Dengue is one of the most common arthropod-borne viral (arboviral) illness in humans. It is transmitted by mosquitoes of the genes aedes-principally aedes aegypti. Present study focuses on the haematological changes in serologically proven dengue positive patients in tertiary care hospital.   Methods: Retrospective observational study was conducted amongst NS1antigen/IgM dengue positive dengue patients in a tertiary care hospital for a period of 6 months.Complete hemogram of one hundred patients was studied and analysed.   Result: Out of the 100 patients studied, 65% patients were in 12-30 years age groups and 75% were males. Leucopoenia was noticed in 36% of cases. Thrombocytopenia at presentation was seen in 94 % of cases. Raised liver serum transaminases, predominantly SGOT were found in 16 out of 20 patients.   Conclusion: Fever associated with thrombocytopenia, leucopoenia and elevated liver transaminases should prompt a clinician on the possibility of dengue infection. Platelet transfusions have a little role in management of dengue patients.

Author Biographies

Vishva Narendrabhai Jethva, Govt. Medical College, Bhavnagar, Gujarat, India
Pathology Department
Mayuri Vasudevbhai Thaker, Govt. Medical College, Bhavnagar, Gujarat, India
Pathology Department


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Original Article