Extra Nodal Primary Diffuse Large B-Cell Lymphoma of Thyroid
A Review of Literature
Keywords:
Thyroid, Lymphoma, Primary, Diffuse Large B-cell Lymphoma, DLBCL, Primary Thyroid Lymphoma
Abstract
Primary Thyroid Lymphoma (PTL) involves less than 5% of all thyroid malignancies. It mostly comes into notice later in life of which Diffuse Large B-Cell Lymphoma (DLBCL) is the commonest type. Though the primary site of lymphoma is Lymph Node, DLBCL involving thyroid primarily and later spreading to Lymph Nodes and other sites is also known. This tumor causes rapid progression of the thyroid mass which can compress the trachea and may even present as an acute emergency. Therefore, it is important to recognize this entity as the treatment and progression differs from other thyroid malignancies We are presenting the case of Extra Nodal Primary DLBCL of Thyroid gland in a 55 years old female who presented with thyroid swelling along with multiple Cervical Lymph Nodes which on Histopathology and subsequent Immunohistochemistry was confirmed as DLBCL of primary thyroid gland with regional and distant metastases.References
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2. Babu KG, Lakshmaiah KC, Lokanatha D, Babu MS, Suresh TM, Rao CR, Premalata CS, Abraham LJ, Lokesh KN. Diffuse large B cell lymphoma of the thyroid: Seven cases with review of the literature from India. Oncology, Gastroenterology and Hepatology Reports. 2015 Jul 1;4(2):81-4.
3: Rosai J, Tallini G, Thyroid Gland. In. Houston M, editor. Rosai and Ackerman’s Surgical Pathology, 10th ed. United States; Elsevier Mosby; 2011. p. 535-4.
4. Vigliar E, Caleo A, Vitale M, Di Crescenzo V, Garzi A, Zeppa P. Early cytological diagnosis of extranodal stage I, primary thyroid Non-Hodgkin lymphoma in elderly patients. Report of two cases and review of the literature. BMC surgery. 2013 Oct;13(2):S49.
5. Hunt KE, Reichard KK. Diffuse large B-cell lymphoma. Archives of pathology & laboratory medicine. 2008 Jan;132(1):118-24.
Published
2019-02-17
Issue
Section
Case Report
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