Lesions of The Eyeball and Ocular Adnexa - Our Experience Over A Period of 18 Months
Keywords:
ocular adnexa, eyeball lesions
Abstract
BACKGROUND: The eyeball is a unique sensory organ, with a varied spectrum of lesions, which are rare with subtle presentation, thus posing diagnostic challenges. Our aim is to evaluate histomorphology of lesions of eye and ocular adnexa, classify and compare with other studies. METHODS: All biopsies and specimens of eyelid, eyeball and orbital lesions received in histopathology section of our Pathology department between January 2017 and June 2018 were analysed and a total 43 cases were evaluated. RESULTS: The age distribution of cases analysed ranged from 6 years to 85 years with mean age of 39 years and equal gender distribution. Neoplastic lesions (53.49%) were more common than non-neoplastic lesions. Among neoplastic lesions, benign (56.52%) were more common than malignant. The most common non-neoplastic lesion was zygomycosis of orbit (75%), epidermal cyst in eyelid (30%) and granulation tissue in eyeball (50%).The only benign tumour in orbit was meningioma. The most common benign tumour in eyelid was hemangioma (50%) and in eyeball, we encountered 1 pigmented nevus of conjunctiva and 1 apocrine hidrocystoma. Common malignant eyelid tumours were basal cell carcinoma and sebaceous carcinoma(33.33% each) , whereas in orbit we received 1 basal cell carcinoma and 1 adenoid cystic carcinoma. In eyeball, we encountered 1 basal cell carcinoma and 1 squamous cell carcinoma of conjunctiva. CONCLUSION: Most of the studies done in this arena focus on either adnexa or orbit alone, and through our study we have tried to understand the frequency of occurrence and histomorphology of all lesions pertaining to eyeball, orbit and adnexa .References
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16. Sunderraj P. Malignant tumours of the eye and adnexa. Indian J Ophthalmol. 1991 Jan-Mar; 39(1):6-8.
17. Roh KK, Lee JH, Youn DH. Clinical analysis of tumors of the eye and its adnexa. Korean J Ophthalmol. 1988 Jun; 2(1):27-31.
18.Marshall EC et al. Epidemiology of tumors affecting the visual system. Optom Clin. 1993; 3(3):1-16.
19. Mondal SK, Nag DR, Bandyopadhyay R, Adhikari A, Mukhopadhyay S. Conjunctival biopsies and ophthalmic lesions: A histopathologic study in eastern India. J Res Med Sci. 2012 Dec; 17(12):1176-9.
20. Thakur SK, Sah SP, Lakhey M, Badhu BP. Primary malignant tumours of eye and adnexa in Eastern Nepal. Clin Exp Ophthalmol.2003 Oct; 31(5):415-7.
2. Chauhan SC et al. A histopathological study of ophthalmic lesions at a teaching hospital. National Journal of Medical Research.2012;2:133-36.
3. Sheikh, Shah Alam et al. Spectrum of ocular lesions in a tertiary care centre: a five year retrospective study. International Journal of Research in Medical Sciences.2016;4(5):1355-1360.
4. Ud Din N et al. Morphological Spectrum of Ophthalmic Tumors in Northern Pakistan. Journal of Pakistani Medical Association. January 2001; 51(1):19-22.
5. Onwubuya, Ifeyinwa Mary et al. Morphological Spectrum of Orbitoocular Diseases in a Tertiary Health Centre in Keffi, North Central Nigeria. Advances in Medicine.2015;2015:619414.
6. Krishnamurthy, Hemalatha et al. A clinicopathological study of lacrimal fossa
lesions at a tertiary care centre. Journal of evolution of medical and dental sciences.2016; 6(91): 6431-6433.
7. Kehinde, Monsudi et al. Histopathological study of ophthalmic tumours and
masses in a tertiary hospital in north-western Nigeria. Annals of Clinical Sciences. March 2017; 2(1): 1-12.
8. Paul, Rita et al. Tumors of the eyelid - a histopathological study at tertiary care
hospitals in Dhaka, Bangladesh. IMC J Med Sci. 2017; 11(1): 5-10.
9. Silas, Olugbenga et al. A Descriptive Study of Patterns of Conjunctival Lesions in Jos,
Nigeria: A 10-year Retrospective Study. Annals of Tropical Pathology. January 2017;8(1) :37-41.
10. Vlad Costan, Victor et al. Histopathological and clinical characteristics of surgically
removed cavernous venous malformations (so-called cavernous hemangiomas) of the orbit. REV.CHIM. (Bucharest).2019;70(1).
11. Tendler, Irwin et al. Primary extradural ectopic orbital meningioma. Ophthalmic Plastic and reconstructive surgery. 2017; 33(1):99-101.
12. Obata H, Aoki Y, Kubota S, Kanai N, Tsuru T. Incidence of benign and malignant lesions of eyelid and conjunctival tumours. Nippon Ganka Gakkai Zasshi. 2005;109(9):573–79.
13. Kapurdov A, Kapurdova M. Clinical, morphological and epidemiological data on eye tumours. Trakia J of Sciences.2010;8(4):34–39.
14. Abdi U, Tyagi N, Maheshwari V, Gogi R, Tyagi SP. J Indian Med Assoc. 1996 Nov; 94(11):405-9, 416, 418.
15. Kumar R, Adhikari RK, Sharma MK, Pokharel DR, Gautam N. Pattern of ocular malignant tumours in Bhairahwa, Nepal. The Internet Journal of Ophthalmology and Visual Science. 2009;7(1).
16. Sunderraj P. Malignant tumours of the eye and adnexa. Indian J Ophthalmol. 1991 Jan-Mar; 39(1):6-8.
17. Roh KK, Lee JH, Youn DH. Clinical analysis of tumors of the eye and its adnexa. Korean J Ophthalmol. 1988 Jun; 2(1):27-31.
18.Marshall EC et al. Epidemiology of tumors affecting the visual system. Optom Clin. 1993; 3(3):1-16.
19. Mondal SK, Nag DR, Bandyopadhyay R, Adhikari A, Mukhopadhyay S. Conjunctival biopsies and ophthalmic lesions: A histopathologic study in eastern India. J Res Med Sci. 2012 Dec; 17(12):1176-9.
20. Thakur SK, Sah SP, Lakhey M, Badhu BP. Primary malignant tumours of eye and adnexa in Eastern Nepal. Clin Exp Ophthalmol.2003 Oct; 31(5):415-7.
Published
2019-08-01
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