Primary Thyroid Schwannoma with Papillary Carcinoma and Hurtle Cell Adenoma in a Background of Hashimoto’s Thyroiditis
A Very Rare Occurrence
Keywords:
Schwannoma, papillary carcinoma thyroid (PTC), hurthle cell adenoma, multiple thyroid nodules
Abstract
Schwannomas are common benign neurogenic tumours that arise from Schwann cells of nerve roots; up to 45% arise in head and neck. However primary thyroid schwannomas are extremely rare. Among thyroid tumours papillary carcinoma of thyroid (PCT) are the most common. Hurthle cell neoplasms are also rare. In addition occurrence of all the three neoplasms in the same patient is extremely rare. In this report we discuss a case of left lobe intrathryroidal schwannoma with papillary carcinoma of thryroid (PCT), Hurthle cell adenoma and background Hashimoto thyroiditis in a 25 year old female. On FNAC it was diagnosed as colloid nodule with cystic change, total thyroidectomy was done and histopathological examination showed that the largest well circumscribed nodule was a benign neurogenic tumour, schwannoma (left lobe of thryroid gland). There were other smaller thyroid nodules; one showing papillary carcinoma with lymph node metastasis and other showing hurthle cell adenoma with background Hashimoto’s thyroiditis.References
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11. Yildirim G, Gillenwater AM, Ordonez NG, Garden AS, El-Naggar AK (2008) Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease. Head Neck 30: 675–679
12. Papi G, Corrado S, LiVolsi VA. Primary spindle cell lesions of the thyroid gland; an overview. Am J Clin Pathol. 2006 Jun;125 Suppl:S95-123. Review.
2. Lee YS, Kim JS, Chung AM, Park WC, Kim T-J. Primary Neurilemmoma of the Thyroid Gland Clinically Mimicking Malignant Thyroid Nodule. Journal of Pathology and Translational Medicine. 2016; 50(2):168-171
3. LiVolsi VA Papillary thyroid carcinoma: an update. Modern Pathology 2011; 24:S1–S9.
4. Okere P, Olusina DB, Enyinnah MO. Hurthle cell tumor of the thyroid gland: Report of a rare case and review of literature. Niger J Clin Pract 2014; 17:375-7.
5. Bradly DP, Reddy V, Prinz RA, Gattuso P. Incidental papillary carcinoma in patients treated surgically for benign thyroid diseases. Surgery. 2009 Dec;146(6):1099-104
6. Agrawal P, Garg N, Jain P. Primary Schwannoma of Thyroid Gland in an Adolescent Male: a Rare Case-report with Review of Literature.Annals of Pathology and Laboratory Medicine, Vol. 03, No. 01, January - March 2016
7. Şahin Mİ, Vural A, Yüce İ, Çağlı S, Deniz K, Güney E. Thyroid leiomyosarcoma: presentation of two cases and review of the literature. Braz J Otorhinolaryngol. 2016 Nov - Dec; 82(6):715-721. doi: 10.1016/j.bjorl.2015.11.020. Epub 2016 Mar 29. Review.
8. Delaney WE, Fry KE. Neurilemoma of the thyroid gland. Ann Surg 1964; 160: 1014-7.
9. Dhar H, Dabholkar JP, Kandalkar BM, Ghodke R. Primary thyroid schwannoma masquerading as a thyroid nodule. Journal of Surgical Case Reports. 2014;2014(9):rju094
10. Repplinger D, Bargren A, Zhang Y-W, Adler J, Haymart M, Chen H. Is Hashimoto’s thyroiditis a risk factor for papillary thyroid cancer? The Journal of surgical research. 2008; 150(1):49-52. doi:10.1016/j.jss.2007.09.020
11. Yildirim G, Gillenwater AM, Ordonez NG, Garden AS, El-Naggar AK (2008) Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease. Head Neck 30: 675–679
12. Papi G, Corrado S, LiVolsi VA. Primary spindle cell lesions of the thyroid gland; an overview. Am J Clin Pathol. 2006 Jun;125 Suppl:S95-123. Review.
Published
2019-08-26
Issue
Section
Case Report
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