Profile of Eyelid lesions: A Histopathological Study from a Tertiary Care Centre in Ajmer
Keywords:
Eyelid tumor, pathology, epidermal cyst, Basal cell carcinoma
Abstract
Background: The literature is relatively sparse on the epidemiological and histopathological profile of eyelid lesions in Rajasthan. The present study aims to characterize the histopathological profile of both non-neoplastic and neoplastic eyelid lesions from a tertiary care centre in Ajmer, Rajasthan. Methods: A total of 55 lesions with histopathology diagnosis were included. Inflammatory non neoplastic lesions were excluded (15.38%). The lesions were categorized into three groups according to the origin: epidermal, adnexal tumors and ‘others’, including melanocytic, vascular lesions and others. Result: Total 55 biopsy specimens were evaluated of which, 44 cases (80%) were benign, 10 cases (18.18%) were malignant and single case (1.81%) was pre malignant. The age distribution varied from 2-81 years with mean age of 36.75 years. Benign lesions were seen more commonly in young boys of first decade and malignant lesions were more frequent in adult females. Most common benign tumors included epidermal cyst (31.81%) followed by hemangioma (18.18%), squamous papilloma (9.09%). Six cases of adnexal tumors (9.23%) were also noted. The most frequent malignant tumor included Basal cell carcinoma (81.81%). Only single case of sebaceous gland carcinoma was seen.References
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28. Bianciotto C, Demirci H, Shields CL, et al (2009). Metastatic tumors to the eyelid: report of 20 cases and review of the literature. Arch Ophthalmol, 127, 999-1005.
2. Abdi UN, Tyagi V, Maheshwari V, Gogi R, Tyagi SP. Tumors of eyelid: A clinicopathologic study. J Indian Med Assoc. 1996;94:405-9.
3. Abe MY, Ohnishi Y, Hara Y, Shinoda Y, Jingu K; Malignant tumor of the eyelid-Clinical Survey during 22-year period. Jpn J Ophthalmol. 1983;27:175-84.
4. Al-Buloushi A, Filho JP, Cassie A, Arthurs B, Burnier MN. Basal cell carcinoma of the eyelid in children: A report of three cases. Eye. 2005;19:1313-4.
5. Rathod A, Pandharpukar M, Toopalli K, Bele S. A clinicopathological study of eyelid tumors and its management at a tertiary eye care centre of Southern India. MRIMS J Health Sci. 2015;3(1):54-8.
6. Myers M, Gurwood AS. Periocular malignancies and primary eye care. Optometry. 2001;72(11):70512.
7. Nithithanaphat C, Ausayakhun S, Wiwatwongwana D, Mahanupab P. Histopathological diagnosis of eyelid tumors in Chiang Mai University Hospital. J Med Assoc Thai. 2014;97(10):1096-9.
8. Karan S, Nathani M, Khan T, Ireni S, Khader A. Clinicopathological study of eye lid tumors in Hyderabad - A review of 57 cases. J Med Allied Sci. 2016;6(2):72-6.
9. Mary Ho, David TL Liu, Kelvin KL Chong, HK Ng, Dennis SC Lam. Eyelid tumours and pseudotumours in Hong Kong: a ten-year experience. Hong Kong Med J. 2013;19:150-5.
10. Yanoff M., Fine B.S. Ocular pathology. 5th ed. vol. 17. Mosby Inc.; 2002. (Ocular melanocytic tumors). p. 641–51 (6 (185), p. 193–4)
11. Bagheri A, Tavakoli M, Kanaani A, Zavareh R B, Esfandiari H, Aletaha M, Salour H. Eyelid Masses: A 10-year Survey from a Tertiary Eye Hospital in Tehran: Middle East African Journal of Ophthalmology Jul 9, 2013: vol 20, issue 3: page187-192.
12. Paul S, Dat T. Vo, Rona Z. Silkis et al: Malignant and Benign Eyelid Lesions in San Franscisco: Study of a Diverse Urban Population:American Journal of Clinical Medicine- Winter 2011, Volume Eight, Number One: page 40-46
13. Cook BE, Jr, Bartley GB. Epidemiologic characteristics and clinical course of patients with malignant eyelid tumors in an incidence cohort in Olmsted County, Minnesota. Ophthalmology. Apr 1999; 106 (4):746-750.
14. Deprez M, Uffer S. Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature. Am J Dermatopathol. 2009;31(3):256-62.
15. Hsu HC, Lin HF. Eyelid tumors in children: a clinicopathologic study of a 10-year review in southern Taiwan. Ophthalmologica
16. Yasser H. Al-Faky Epidemiology of benign eyelid lesions in patients presenting to a teaching hospital. Saudi Journal of Ophthalmology (2012) 26, 211–216.
17. Obata H, Aoki Y, Kubota S, Kanai N, Tsuru T Incidence of benign and malignant lesions of eyelid and conjunctival tumors. Nihon Ganka Gakkai Zasshi. 2005 Sep; 109 (9): 573-9.
18. Pornpanich K, Chindasub P. Eyelid tumors in Siriraj Hospital from 2000-2004. J Med Assoc Thai. 2005; 88: S11–4.
19. Kersten RC, Ewing-Chow D, Kulwin DR, Gallon M. Accuracy of clinical diagnosis of cutaneous eyelid lesions. Ophthalmology 1997; 104: 479-84.
20. Ni Z. Histopathological classification of 3510 cases with eyelid tumor. Zhonghua Yan Ke Za Zhi 1996; 32 (6): 435–7.
21. Chi MJ, Beak SH. Clinical analysis of benign eyelid and conjunctival tumors. Ophthalmologica 2006; 220: 43–51.
22. Tesluk GC, Eyelid lesions: incidence and comparison of benign and malignant lesions. Ann Ophthalmol. 1985;17(11):704-707.
23. Sanjay C, Sejal S, Piyush S, Falguni S, Cherry S, Nailesh S. Accuracy of Clinical Diagnosis of Eyelid Lesion In A Medical College In Gujarat. Int J Res Med. 2013; 2(1);114-117
24. Fouzia F, Qamar J, Mahmood S, Zia G. Evaluation of Eyelid Lesions at a Tertiary Care Hospital, Jinnah Postgraduate Medical Centre (JPMC), Karachi. Pak J Ophthalmol 2010;Vol. 26 No.2:83-86
25. Krishnamurthy H, Tanushree V, Venkategowda H. T, Archana S, Mobin G, et al. Profile of eyelid tumors at tertiary care institute in Karnataka: A 5Years Survey. J Evolut Med Dent Sci. 2014;3(50):11818-32.
26. Bhavya P. Mohan, Letha V. Profile of eye lid lesions over a decade: a histopathological study from a tertiary care center in South India International Journal of Advances in Medicine. Int J Adv Med. 2017 Oct;4(5):1406-1411.
27. Dasgupta T, Wilson LD, Yu JB. A retrospective review of 1349 cases of sebaceous carcinoma. Cancer. Jan 1 2009; 115 (1): 158-165. 3117. Shastry Shrikanth. Spectrum of histopathological study of ocular lesions – 1 year study. Journal of Dr. NTR University of Health Sciences. 2014;3(1):12-14.
28. Bianciotto C, Demirci H, Shields CL, et al (2009). Metastatic tumors to the eyelid: report of 20 cases and review of the literature. Arch Ophthalmol, 127, 999-1005.
Published
2019-05-01
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