Clinico-Pathological Study of Tubal Ectopic Gestation and Evaluation of Associated Risk Factors in A Tertiary Care Centre

  • Archana S Bembde Aurangabad, Maharashtra.431003 India
  • Suparna M Bindu Aurangabad, Maharashtra.431003 India
  • Chandrashekar P Bhale Aurangabad, Maharashtra.431003 India
Keywords: Ectopic gestation, Salphingitis Isthmica Nodosa, Pelvic inflammatory disease, Salphingitis.

Abstract

Background: Ectopic gestation is an obstetric emergency with high morbidity and mortality. Most common site for ectopic pregnancy is fallopian tube. Predisposing risk factors include pelvic inflammatory disease (PID) that is acute and chronic salpingitis, previous abortion, Salphingitis Isthmica Nodosa (SIN); and treatment for infertility. This study was done to identify the common risk factors. Method: This was a retrospective study carried out for the period of 6 years (January 2013 - December 2018) in M.G.M. Medical college, Aurangabad. 110 cases of tubal ectopic gestations were studied. Results: Out of 110 ectopic gestations, commonest age of presentation was 25-35years (90.9%), and were multiparous (85.3%). Right sided tube was mostly affected (70.2%), with the risk factors of PID (32%) and previous abortion (30%). Most of the patients presented with pain in abdomen (40.90%) and amenorrhea (31.81%). Predominant histopathological findings were chronic salphingitis with follicular salphingitis (40.90%), acute salphingitis (27.27%) and SIN (22.7%). Conclusion: Pelvic inflammatory disease, Salphingitis Isthmica Nodosa, acute and chronic salphingitis are predisposing factors for tubal ectopic gestation. Early diagnosis, identification of risk factors and timely intervention will reduce the incidence of ectopic pregnancy and also will help in reducing morbidity and mortality associated with it.

Author Biographies

Archana S Bembde, Aurangabad, Maharashtra.431003 India
Department of Pathology
Suparna M Bindu, Aurangabad, Maharashtra.431003 India
Department of Pathology
Chandrashekar P Bhale, Aurangabad, Maharashtra.431003 India
Department of Pathology

References

1. Swetha D, Amitha K. A clinical study of ectopic pregnancy in a tertiary care center in Hubli. International journal of reproduction, contraception, obstetrics and gynaecology. 2017 Apr; 6(4): 1566-1569.
2. Mridula S, Hemlata P, Jyoti N M. A clinical study of ectopic pregnancy in a tertiary care center in central India. International journal of reproduction, contraception, obstetrics and gynaecology. 2017 Jun; 6(6): 2485-2490.
3. Vandana B, Smiti N, Menakshi C, Vani M. A retrospective analysis of ectopic pregnancy at a tertiary care center: one year study. International journal of reproduction, contraception, obstetrics and gynaecology. 2016 Jul; 5(7): 2224-2227.
4. Savithri R, Sruthi P, Belur V S. Histomorphology of fallopian tubes in ectopic pregnancy. Arch Med Health Sci 2016; 4:201-204.
5. Rajendra W, Kshama K. Ectopic pregnancy- A rising trend. International journal of scientific study, 2015 Aug; 3 (5): 18-22.
6. Dahiya, S. Singh, R. Kalra, R. Sen and S. Kumar. Histopathological changes associated with ectopic tubal pregnancy. International journal of pharmaceutical sciences and research. 2011 Apr; 26: 929-933.
7. Mohd I A, Zeenath B. A study on histopathological findings in ectopic tubal pregnancies and evaluation of associated risk factors. Indian journal of Pathology: Research and practice. 2018 Aug; 7(8): 928-933.
8. Smita K, Dipali P, Archana S, Sadia P. Retrospective study of ectopic pregnancy in a tertiary care center. International archives of integrated medicine. 2018 Jan; 5(1): 95-99.
9. Shraddha S K., Anil S K. A clinical study of ectopic pregnancies in a tertiary care hospital of Mangalore, India. Innovative journal of medical and health science. 2014 Jan; 4(1): 305-309.
10. Arup KM, Niloptal R, Kakali SK, Pradip KB. Ectopic pregnancy- an analysis of 180 cases. Journal of the Indian Med Assoc. 2007;105:308-14.
11. ICMR: ICMR task force project: Multicenter case control study of ectopic pregnancy in India. J Obstet Gynaecol India. 1990;40:425-30.
12. Khaleeque F, Siddiqui RI, Jafarey SN. Ectopic pregnancies: A three year study. J Pak Med Assoc 2001;51:240-3.
13. Shrestha J, Saha R. Comparison of laparoscopy and laprotomy in the surgical management of ectopic pregnancy. J coll physicians Surgpak. 2012; 22(12): 760-764.
14. Kamwendo F, Forslin L, Bodin L, Danielsson D. epidemiology of ectopic pregnancy during a 28 year period and the role of pelvic inflammatory disease. Sex Transm Infect 2000; 79:28-32.
15. Green LK, Kott ML. histopathologic findings in ectopic tubal pregnancy. Int J Gynaecol Pathol 1989;8:255-62.
16. Persaud V. etiology of tubal ectopic pregnancy. Radioloic pathlogic studies. Obstet Gynaecol 1970; 36:257-63.
Published
2019-06-28
Section
Original Article