Cytomorphology of Chondroid Syringoma: Analysis of 20 Cases and Review of Literature

  • Meetu Agrawal Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • Mukul Singh Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • Rituraj . Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • Sachin Kolte Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • C Ahluwalia Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • Neha Madan Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • Rasmi Aurora Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
Keywords: Chondroid syringoma, Skin adnexal tumors, Cytomorphological variation, Chondromyxoid

Abstract

Background: Chondroid syringomas [CS] are interesting skin adnexal tumours. They have a remarkable pleomorphic-adenoma like morphology in the skin. Though the histopathology of the tumour has been described in detail in literature, cytomorphological studies are restricted to case reports and small case series. For diagnosing a CS on cytology, the index of suspicion must be high, clinical evaluation must be thorough and knowledge of variant existing morphologies is essential. Aim: This study was done with the aim of studying the common and variant cytological features of chondroid syringomas. Methods: This was a retrospective study conducted over a four-year period (2014-17) in the Department of Pathology, VMMC and Safdarjung hospital. Fine needle aspirate smears and biopsy slides were studied. Morphological details were independently reviewed in detail by two pathologists (Dr MS and Dr MA). Result and Conclusion: The conventional biphasic cell morphology of CS was seen in nearly 50% cases. Rest of the cases showed predominance of one or more variant features in few areas and thus CS was only one of the differential diagnosis in these cases. Nevertheless, FNA proved to be fast, inexpensive and a reliable method for diagnosis of chondroid syringoma. The study will be relevant and helpful in the day to day cytological reporting of CS.

Author Biographies

Meetu Agrawal, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
Department of Pathology
Mukul Singh, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
Department of Pathology
Rituraj ., Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
Department of Pathology
Sachin Kolte, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
Department of Pathology
C Ahluwalia, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
Department of Pathology
Neha Madan, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
Department of Pathology
Rasmi Aurora, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
Department of Pathology

References

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Published
2019-12-01
Section
Review Article