Adenoid Cystic Carcinoma of Nasal Cavity

A Rare Case Report

  • Arpita J. Nishal Government Medical College, Surat, Gujarat, India
  • Mubin Patel Government Medical College, Surat, Gujarat, India
  • Neha S. Shahu Government Medical College, Surat, Gujarat, India
Keywords: Adenoid cystic carcinoma, Nose, Salivary gland, Rare presentation


Adenoid cystic carcinoma (ACC) was first described by billroth in 1856. It is common in minor salivary glands around the mouth, uncommon in parotids and in Nose and paranasal sinuses. Sinonasal ACC accounts for 10-25% of all head and neck ACC. We are reporting a case of nasal cavity adenoid cystic carcinoma in a 70 year old male patient who was presented with bilateral nasal block, nasal bleeding and loss of vision. On examination polypoidal growth was present in bilateral nasal cavity. Biopsy was taken and sent for histopathological examination. Histopathological findings were suggestive of adenoid cystic carcinoma of nasal cavity. ACC is a slow-growing but highly malignant neoplasm with a remarkable capacity for recurrence. They show no sex predilection and may involve patients of any age, although they usually present in middle-aged or older patients. It has a high risk of recurrence and distant metastasis. Features of diagnostic and therapeutic evaluation are described here with.

Author Biographies

Arpita J. Nishal, Government Medical College, Surat, Gujarat, India
Department of Pathology
Mubin Patel, Government Medical College, Surat, Gujarat, India
Department of Pathology
Neha S. Shahu, Government Medical College, Surat, Gujarat, India
Department of Pathology


1. Purushothaman PK, Ramakrishna R, Sindhu P. Adenoid Cystic Carcinoma of Nasal Cavity: A Rare Presentation Case Report. International Journal of Scientific and Research Publications, Feb 2015; Vol5(2):1-3
2. Steven G. Silverberg, Ronal A. De Lellis, William J. Frable, Virginia A. Livolsi, Mark R. Wick. Silverberg’s Principles and practice of Surgical pathology and Cytopathology, 4th edition, Volume 1. Churchill Livingstone: Elsevier; 2006:1221-1246.
3. Kumar VP, Rao PN, Kumar AG. Adenoid Cystic Carcinoma of Nasal Cavity- A case report. Indian journal of Orolaryngology and Head and Neck Surgery, January-March 2003; Vol. 55:43-45.
4. Goldblum JR, Laura W. Lamps, Jesse K. McKenny. Rosai and Ackerman’s, textbook of surgical pathology. 11th edition, Elsevier;2018:252-253.
5. Phan J, No S, Pollard Iii C, et al. A Rare Case of Unresectable Adenoid Cystic Carcinoma of the nasopharynx Treated with Intensity Modulated Proton Therapy. 2017;Cirrus 9(9):e1688. doi:10.7759/cureus.1688.
6. Edward B. Stelow and Stacy E. Mills: Biopsy Interpretation of Upper Aerodigestive Tract and Ear. Philadelphia: Lippincott Williams & Wilkins, a Wolters Kluwer,2nd edition;2012:104-119.
7. Jagmohan P, Sangwan S, Sethi S K, Solanki R S. Sinonasal adenoid cystic carcinoma. Indian J Radiol Imaging, 2005;15:403.
8. Stacey E Mills MD: Sternberg's Diagnostic Surgical Pathology, Sixth Edition;2015:2565-2566
9.EI-Naggar A.K., Chan J.K.C., Grandis J.R., Takata T., Slootweg P.J. (Eds): WHO Classification of Head and Neck Tumours (4th edition). IARC: Lyon 2017:164
10. Pournima Hodge, Subhadra Sharma, Monika Yadav: Adenoid cystic carcinoma of the parotid gland. Contemporary Clinical Dentistry, Apr-Jun 2012; 3(2):223-226.
11. David, J. Dabs: Diagnostic immunohistochemistry, 3rd edition. Churchill Livingstone: Elsevier; 2010:275-276
Case Report