Epithelioid Sarcoma: A Case Report

  • Pooja Jain Kasturba Medical College Manipal, Manipal, Karnataka, India
  • Ranjini Kudwa Kasturba Medical College Manipal, Manipal, Karnataka, India
Keywords: Rare, Epithelioid Sarcoma, aggressive

Abstract

Epithelioid sarcoma is a rare highly aggressive soft tissue sarcoma with a high incidence of local recurrence and metastasis. It is a tumor of uncertain histogenesis & poses a diagnostic difficulty as it is often misdiagnosed as other benign or malignant condition. We present the case of 49-year-old male presenting with chief complaints of pain and gradually progressive swelling on right 3rd toe since 3 months. Based on clinicoradiological evaluation suggestive of malignancy, an amputation of toe was done. Histopathological & Immunohistochemical findings suggestive of Epithelioid sarcoma. The patient was referred to the oncology centre for further management where he was advised wide excision followed by radiotherapy. No regional or distant metastasis was found.

Author Biographies

Pooja Jain, Kasturba Medical College Manipal, Manipal, Karnataka, India
Department of Pathology
Ranjini Kudwa, Kasturba Medical College Manipal, Manipal, Karnataka, India
Department of Pathology

References

1. Enzinger FM. Epithelioid sarcoma: a sarcoma simulating a granuloma or a carcinoma. Cancer. 1970;26:1029–1040

2. Rekhi, B., Gorad, B.D. & Chinoy, R.F. Proximal-type epithelioid sarcoma – a rare, aggressive subtype of epithelioid sarcoma presenting as a recurrent perineal mass in a middle- aged male. World J Surg Onc 5, 28 (2007) doi:10.1186/1477-7819-5-28

3. Laila C, Louis G, Philippe T, Anne V D, Fleur G, Marie JTL, Dominique R, Yves M R, Françoise C, Paul F, Jean M C, Epithelioid Sarcoma: A Clinicopathologic and Immunohistochemical Analysis of 106 Cases From the French Sarcoma Group, American Journal of Clinical Pathology, Volume 131, February 2009, Pages 222–227.

4. Weiss SW, Goldblum JR. Malignant soft tissue tumors of uncertain type. In: Enzinger FM, Weiss SW, editors. Soft tissue Tumors. 4th ed. St Louis: Mosby; 2001. p. 1521-38.

5. Billings SD, Folpe AL, Weiss SW. Epithelioid sarcoma-like hemangioendothelioma. Am J Surg Pathol 2003;27:48-57.

6. Spillane AJ, Thomas JM, Fisher C. Epithelioid sarcoma: The clinicopathologic complexities of this rare soft tissue sarcoma. Ann Surg Oncol 2000;7:218-25

7. Ross HM, Lewis JJ, Woodruff JM, Brennan MF. Epithelioid sarcoma: Clinical behavior and prognostic factors of survival. Ann Surg Oncol 1997;4:491-5.

8. Miettinen et al.: Epithelioid sarcoma: An immunohistochemical analysis of 112 classical and variant cases and a discussion of the differential diagnosis. Human Pathology Volume 30, Issue 8, Pages 934-942. Aug 1999.
Published
2020-04-29
Section
Case Report