Diagnostic Utility of Bronchoalveolar Lavage and Bronchial Brush Cytology in Lung Lesions
Keywords:
bronchoalveolar lavage, bronchial brush cytology, bronchogenic carcinoma, adenocarcinoma, squamous cell carcinoma, bronchial washings
Abstract
Background: In 1960’s, flexible fiberoptic bronchoscope, was first used to give a better yield to diagnose pulmonary diseases. Bronchial brushing cytology (BBC) and Broncho-alveolar lavage (BAL) are two important adjuncts done along with bronchoscopic biopsy. Bronchial brushings yield better diagnostic material than simple exfoliative cytology. Therefore, both techniques are of much diagnostic value and is widely accepted as it is safe, economical and evaluation requires much less time. Methods: All the bronchial brush and bronchoalveolar lavage smears obtained from January 2018 to December 2018 were assessed. Correlation was done with histopathology wherever was available. Result: BBC showed a sensitivity and specificity of 59.28% and 100%. The positive predictive value and negative predictive value were 100% and 47.62%. BAL showed a sensitivity and specificity of 51% and 100%. The positive predictive value and negative predictive value was 100% and 43.18%. The diagnostic accuracy of BBC and BAL were 70.27% and 64.86%. Conclusion: Universally bronchial washings and bronchial brushings should be considered important adjunct to bronchoscopic biopsies to diagnose pulmonary lesions as both are safe, economical and can will give better diagnostic yield if incorporated together.References
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2. Kocjan G, Gray W, Vielh P, Levine T, Kardum-Skelin I. Diagnostic Cytopathology Essentials E-Book. Elsevier Health Sciences; 2013 May 8.
3. Cibas ES, Ducatman BS. Cytology E-Book: diagnostic principles and clinical correlates. Elsevier Health Sciences; 2013.
4. Raiza D, Rout S, Reddy KP, Ramalaxmi PV, Prithvi BK, Harikishan KS. Efficacy of bronchial wash and brush cytology and its correlation with biopsy in lung lesions. Int J Health Res Mod Integr Health Sci. 2014;3:21-4.
5. Behura A, Rao KM. BRONCHOSCOPIC BRUSH CYTOLOGY IN THE DIAGNOSIS OF LUNG LESIONS. group. 2018 Jan 1;21(30):9-34.
6. Dawan S. Efficacy of Bronchial Brushing Cytology and Its Correlation with Biopsy in Lung Tumours At tertiary care Hospital northern western. Journal of Medical science and clinical research. 2017;5(7).
7. Rao S, Rao S, Lal A, Barathi G, Dhanasekar T, Duvuru P. Bronchial wash cytology: A study on morphology and morphometry. Journal of Cytology. 2014;31(2):63.
8. Giti R, Hosseinzadeh M. Efficacy of Bronchial Washing and Brushing Cytology in the Diagnosis of Non-Neoplastic Lung Diseases. Acta Medica Iranica. 2017 Dec 2:636-41.
9. Prakash P, Agarwal P, Dasgupta A, Gahoi K. Study of Diagnostic Efficacy of Bronchoalveolar Lavage and Bronchoscopic Brush Cytology in Clinico-radiologically Suspected Cases of Lung Malignancies.2018 Jan;19(1):22.
10.Tomar V, Vijay N, Nuwal P, Dixit R. Comparative study of bronchoalveolar lavage, bronchial brushing, and FNAC in diagnosing malignant neoplasms of lungs. Journal of cytology. 2016 Oct;33(4):210
Published
2020-08-26
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