Lymphoepithelial Cyst, A Diagnostic Dilemma: Case Report
Keywords:
Lymphoepithelial cyst, Branchial epithelium, Squamous cell carcinoma, HIV Infection
Abstract
Lymphoepithelial cysts are benign, slowly growing unilocular or multilocular lesions that appear in the head and neck region. They are also called branchial cysts and occur due to lymphocyte induced cystic ductular dilatation. The confirmatory diagnosis is always made on histopathological examination after resection. A 29 years old female patient presented to ENT department, Pt B. D. Sharma PGIMS, Rohtak with a soft to firm, non-tender, swelling in the submandibular region since 2 -3 days and was referred to Department of Pathology for FNAC on which a differential diagnosis of infected epidermoid cyst or squamous cell carcinoma was made and excision biopsy for confirmation and categorization was advised. The swelling was then excised and sent for histopathological examination and a final diagnosis of Lymphoepithelial cyst was made. The confirmatory diagnosis is always made postoperatively by histopathological examination. The treatment of a lymphoepithelial cyst is the surgical approach, which includes complete enucleation of the cyst. This is a case report of a lymphoepithelial cyst diagnosed on histopathology specimen for which differential of Infected cyst or Squamous cell carcinoma was given. The authors intend to highlight the importance of early histopathological diagnosis of Benign LEC as it has been reported to undergo malignant transformationReferences
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2. Leite RB, Severo ML, Oliveira PT, Medeiros AM, Barboza CA, Silveira EJ. Lymphoepithelial cyst on the tongue: case report at unusual location. Jornal Brasileiro de Patologia e Medicina Laboratorial. 2017;53(4):273-5.
3. Ahamed AS, Kannan VS, Velaven K, Sathyanarayanan GR, Roshni J, Elavarasi E. Lymphoepithelial cyst of the submandibular gland. J Pharm Bioallied Sci. 2014;6 (Suppl 1):S185-7.
4. Stramandinoli-Zanicotti RT, de Castro Ávila LF, de Azevedo Izidoro AC, Izidoro FA, Schussel JL. Lymphoepithelial cysts of oral mucosa: two cases in different regions. The Bulletin of Tokyo Dental College. 2012;53(1):17-22.
5. Berniar JL, Bhaskar SN, Lymphoepithelial lesions of salivary glands; histogenesis and classifications based on 186 cases. Cancer. 1958;11:1156-79.
6. Himalstein MR, Morfit HM, Ehrlich H. The case of Bracnchiogenic cancer (malignant brachioma). AnnSurg. 1950;132:867.
7. Mhawej R, Richa T, Melkane AE. Benign lymphoepithelial cyst of unusual location: a case report. Acta Otolaryngeal Case Rep. 2016;1:110-2.
8. Skouteris CA, Patterson GT, Stoereanos GC. Benign cervical lymphoepithelial cyst: Report of cases. J Oral Maxillofac Surg. 1989;47:1106-12.
9. Smith AG, Booth RPW. Lymphoepithelial cysts: a maxillofacial surgeon’s perspective. Br J Oral Maxillofac Surg. 1993;31:120-3.
10. Rojas R, Di Leo J, Palacios E, Rojas I, Restrepo S. Parotid gland lymphoepithelial cysts in HIV infection. Ear Nose Throat J. 2003;82:20-2.
Published
2020-10-29
Issue
Section
Case Report
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