Plexiform Schwannoma Masquerading as Giant Cell Tumor of Tendon Sheath- A Case Report

  • Sharanjit Singh Dept of Pathology, Armed Forces Medical College
  • Ganesh Pendkur Dept of Pathology, Armed Forces Medical College
  • Puneet Baveja Dept of Pathology, Armed Forces Medical College
  • Nilanjan Roy Dept of Pathology, Armed Forces Medical College
Keywords: Plexiform, Schwannoma, Giant cell tumor, Neurofibroma, Spindle cells

Abstract

Plexiform schwannoma is a rare benign variant of Schwann cell tumor characterised by multinodular plexiform growth pattern. Usual location of this tumor includes trunk, head, neck and upper extremities but it may rarely be found in lower extremities. It generally affects young adults with no sex predilection. We report a case of 37 years old male who presented with gradually progressive swelling of right little finger of 28years duration that was diagnosed as giant cell tumor of tendon sheath clinically, radiologically and intraoperatively. Authors wish to discuss the case due to its clinical rarity and diagnostic difficulties due to many common histological mimickers at that site.

References

1. Ioannou M, Papanastassiou I, Iakowidou I, Kottakis S, Demertzis N. Plexiform schwannoma of the posterior tibial nerve: a case report. Cases J. 2009;2:8392.
2. Friedman JM. Neurofibromatosis 1: Clinical manifestations and diagnostic criteria. J Child Neurol 2002;17:548-554.
3. Xiupeng Zhang, Guiyang Jiang, Enhua Wang, Xuyong Lin.Mediastinal benign epithelioid schwannoma: a rare tumor in an unreported location. Int J ClinExp Med 2017;10(5):8357-8362.
4. Harkin JC, Arrington JH, Reed RJ. Benign plexiform schwannoma, a lesion distinct from plexiform neurofibroma. J Neuropathol Exp Neurol. 1978;37:622.
5. Berg JC, Scheithauer BW, Spinner RJ, Allen CM, Koutlas IG. Plexiform schwannoma: a clinicopathologic overview with emphasis on the head and neck region. Hum Pathol. 2008;39:633–640.
6. Tassano E, Sementa AR, Tavella E, Garaventa A, Panarello C, Morerio C. Trisomy 17 in congenital plexiform (multinodular) cellular schwannoma. Cancer Genet Cytogenet 2010;203:313-315.
7. Rodriguez FJ, Folpe AL, Giannini C, Perry A. Pathology of peripheral nerve sheath tumors: Diagnostic overview and update on selected diagnostic problems. ActaNeuropathol 2012;123:295-319.
8. Ying Li, Chao Yang Miao, Chen Wang, Xiao-Yan Zhang. Cutaneous Plexiform Schwannoma in right thigh after trauma. Int J Dermatol Venereol.March 2019 ; 2: 45-46.
9. Zainab H, Kale AD, Hallikerimath S. Intraosseous schwannoma of the mandible. J Oral Maxillofac Pathol. 2012;16(2):294‐296.
Published
2020-10-31
Section
Case Report