Case Report of An Unusual Mediastinal Mass - Thymolipoma

  • Sreeja Raju Department of Pathology, Amala Institute of Medical Sciences, Thrissur, Kerala
  • Divya S Department of Pathology, Amala Institute of Medical Sciences, Thrissur, Kerala
  • M C Savithri Department of Pathology, Amala Institute of Medical Sciences, Thrissur, Kerala
  • Ajaykumar KK Department Of Cardiothoracic and Vascular Surgery, Amala Institute Of Medical Sciences, Thrissur, Kerala
  • Gayathri G Nair Department of Pathology, Amala Institute of Medical Sciences, Thrissur, Kerala
Keywords: thymus, mediastinal mass, thymolipoma, thymectomy

Abstract

Thymolipomas are rare, slow-growing, benign anterior mediastinal neoplasms which are very often detected incidentally. Here we present a case of a 47 year old female who presented with chest discomfort and radiology revealed an anterior mediastinal mass. Total thymectomy was done and histopathology showed features consistent with thymolipoma. Very few cases of thymolipomas have been reported in Indian and world literature.

References

Bayramoğlu Z, Ömeroğlu E, Ünlü Y. Thymolipoma with massive pleural effusion: A case report. J Surg Med. 2019;3(3):276–7.

Vaziri M, Rad K. Progressive Dyspnea in a 40-Year-Old Man Caused by Giant Mediastinal Thymolipoma. Case Rep Surg. 2016;2016:1–3.

Reddy RHV, Qureshi NJ. Unusual Mediastinal Tumour of Thymic Origin. Indian J Surg Oncol. 2013;4(3):320–1.

Hall GFM. A case of thymolipoma. With observations on a possible relationship to intrathoracic lipomata. Br J Surg. 1949;36(143):321–4.

Carapinha CP, Wainwright L, Loveland JA. A giant thymolipoma. SAJCH South African J Child Heal. 2010;4(1):20–1.

Obeso Carillo GA, García Fontán EM, Cañizares Carretero MÁ. Timolipoma gigante: presentación de un caso de tumor mediastínico inusual. Arch Bronconeumol. 2014;50(12):557–9.

Rosado-de-Christenson ML, Pugatch RD, Moran CA, Galobardes J. Thymolipoma: Analysis of 27 cases. Radiology. 1994;193(1):121–6.

Hayashi A, Takamori S, Tayama K, Mitsuoka M, Ohtsuka S, Aoyama Y, et al. Thymolipoma : Clinical and Pathological Features - Report of Three Cases and Review of Literature. Kurume Med J. 1997;44:141–6.

Ramos Filho J, Melo RF, De Macedo M, Fiorelli LA, Costa A, Isolatto RB. Chest pain due to right atrial compression caused by a thymolipoma. Arq Bras Cardiol. 2004;82(5):484–6.

Almog C, Weissberg D, Herczeg E, Pajewski M. Thymolipoma simulating cardiomegaly: a clinicopathological rarity. Thorax. 1977;32(1):116–20.

Hudacko R, Aviv H, Langenfeld J, Fyfe B. Thymolipoma: clues to pathogenesis revealed by cytogenetics. Ann Diagn Pathol. 2009;13(3):185–8.

Published
2020-11-30
Section
Case Report